Clinical trials: Body Weight Control
Severe Obesity, Cardiovascular Function
Use of Liraglutide in Children Aged 6 to 12 Years With Severe Obesity
This randomized controlled trial evaluates the efficacy, safety, metabolic, and cardiovascular effects of liraglutide in children aged 6 to 12 years with severe obesity.
- Conditions
- Severe Obesity, Cardiovascular Function, Liraglutide, Childhood Obesity
- Trial name
- NCT07590219
- Testing
- Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Preterm Birth, Health Care Utilization
Health and Wellness After Preterm Birth
This study continues an adaptation of the behavioral intervention Care Coordination After Preterm Birth (CCAPB). This is a pragmatic pilot randomized controlled feasibility trial of CCAPB with baseline and post-intervention…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05756634
- Testing
- Care Coordination after Preterm Birth (CCAPB)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Obesity, Childhood, Binge Eating
Project REST: Regulation of Eating and Sleep Topography
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for…
- Conditions
- Obesity, Childhood, Binge Eating, Sleep, Self-regulation
- Trial name
- NCT04057716
- Testing
- Sleep restriction, Sleep extension
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dysmenorrhea Primary, Obesity and Overweight
Bioptron Light Therapy for Dysmenorrhea in Obese Adolesences: RCT
Dysmenorrhea is the most common health problem in women in the reproductive age(Bakhsh et al., 2022). The primary dysmenorrhea starts shortly after the menarche the pain lasting 1 to 3 days that start just before or at the onset…
- Trial name
- NCT06992349
- Testing
- bioptron light therapy
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Alaa Noureldeen Kora
Child Obesity
Applying Navigation and Care to Help Ongoing Retention
Canada's health care system has established numerous clinics over the past 20 years to treat childhood obesity. However, up to 80% of children at these clinics drop out before they finish treatment.
- Trial name
- ANCHOR (NCT07834632)
- Testing
- Family Navigation, Usual Care
- Where
- Canada
- Volunteers
- 252 people
- Sponsor
- University of Alberta
Obesity, Childhood
Lifestyle Counseling and Medication for Adolescent Weight Management
The prevalence of adolescent severe obesity is at an all-time high in the United States and the refractory nature of this disease has led to a serious and challenging conundrum in terms of how to provide effective, safe…
- Trial name
- QUEST (NCT04873245)
- Testing
- Intensive Behavioral Program, Semaglutide and Behavioral Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Pediatric Obesity
The Peds Obesity Study
The aim of the study is to investigate, in severely obese adolescents, the effects of a high protein, restricted carbohydrates utilizing partial meal replacements diet (HPRC-PMR) on weight loss, body composition, and bio-chemical…
- Trial name
- NCT02353637
- Testing
- Partial Meal Replacements
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Obesity & Overweight, Vulnerable Families
Evaluation of a Multicomponent Early Intervention for Childhood Obesity Prevention in Vulnerable Families
Childhood obesity is a public health concern. Evidence-based, multicomponent, parenting interventions targeting early childhood and adapted to families' socioeconomic context are needed to prevent childhood obesity.
- Conditions
- Obesity & Overweight, Vulnerable Families, Children, Families With Infants
- Trial name
- Bambú (NCT07529704)
- Testing
- Bambú program
- Where
- 4 sites in Spain
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Helena Vall Roqué
Childhood Obesity
Family Connections: Cultural Adaptation and Feasibility Testing for Rural Latino Communities
There are marked ethnic and rural-urban disparities in the prevalence of childhood obesity (CO). Among Latino/Hispanic children, CO is almost 60% higher than that of non- Latino/Hispanic Whites, and among children in rural areas…
- Trial name
- NCT04731506
- Testing
- Family Connections
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Nebraska
Autism Spectrum Disorder, Obesity
Mobile Health Intervention for Children With Autism
This study is a randomized clinical trial conducted in China from January 2023 to July 2025. It aims to test whether a mobile health program delivered via WeChat, with or without additional human support, can help improve body…
- Conditions
- Autism Spectrum Disorder, Obesity, Pediatric Overweight
- Trial name
- WeChat-Autism (NCT07514910)
- Testing
- Standard Lifestyle Recommendations, WeChat-Based Mobile Health Intervention, Coach-Facilitated Tele-Group Sessions
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Hunan Normal University
Obesity, Overweight
Overweight and Obesity in Preschoolers
Obesity interventions in early childhood are recommended as they have been proven to be more effective than interventions later in life.
- Trial name
- MLEurope (NCT03800823)
- Testing
- Parent group, mHealth component, Standard care
- Where
- 3 sites in Romania, Spain and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Overweight and Obesity
School Based Childhood Obesity Feasibility Study
In Bangladesh, the prevalence of overweight and obesity among children varies from less than 1% to 17.9% based on different reference standard.
- Trial name
- NCT03180580
- Testing
- HEAL guideline and healthy tiffin box intervention
- Where
- Bangladesh
- Volunteers
- 831 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Overweight and Obesity
Inhibitory Control and Pediatric Weight Management
The purpose of this pilot study is to explore the benefits of supplementing the Kurbo online program with a cognitive training game (PolyRules!) among youth ages 7-13 with overweight or obesity.
- Trial name
- NCT04747548
- Testing
- Kurbo Only, Kurbo + PolyRules!
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Breast Feeding
Randomized Controlled Trial of Dietary Advice in Primary Care to Promote Healthy Feeding of Infants
A cluster randomized field trial to evaluate the impact that training healthcare workers in healthy feeding practices has on the nutrition and health of children.
- Trial name
- NCT00635518
- Testing
- Ten Steps for Healthy Feeding children programme
- Sponsor
- Federal University of Health Science of Porto Alegre
Rheumatoid Arthritis, Healthy
The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With Etanercept
This study has two phases. Phase 1 will examine the role of inflammatory mediators called cytokines on growth hormone levels in women with rheumatoid arthritis (RA).
- Trial name
- NCT00034060
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Volume-Controlled Ventilation, Pressure-Controlled Ventilation Volume Guaranteed
Volume-Controlled Ventilation and Pressure-Controlled Ventilation Volume Guaranteed in Obese Patients in Laparoscopic-Assisted Surgery
The aim of this study is to compare the efficacy of the pressure controlled ventilation volume-guaranteed (PCV-VG) versus volume-controlled ventilation (VCV) modes as regards lung compliance and oxygenation index in obese…
- Conditions
- Volume-Controlled Ventilation, Pressure-Controlled Ventilation Volume Guaranteed, Obese, Laparoscopy
- Trial name
- NCT06117748
- Testing
- Pressure controlled ventilation-volume guaranteed, Volume controlled ventilation
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Obesity, Genetic Obesity
EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway
The protocol describes a randomized, double-blind, placebo-controlled trial with independent sub-studies of setmelanotide in patients with obesity and at least one of the specific gene variants in the Melanocortin-4 Receptor…
- Trial name
- NCT05093634
- Testing
- Setmelanotide
- Where
- 56 sites in United States, Canada and 8 more
- Volunteers
- 296 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Low Birth Weight, Small for Gestational Age (SGA)
Improving Aspirin Prescription Rates in Outpatient Clinic
Ρrееςlаmpѕia is a syndrome characterised by the new onset of hуреrtеnѕion plus proteinuria, end-organ dysfunction, or both after 20 weeks of gestation. It complicates 3-5% of pregnancies.
- Conditions
- Low Birth Weight, Small for Gestational Age (SGA), Preeclampsia (PE), Prevention &Amp; Control
- Trial name
- NCT06694233
- Testing
- Aspirin prescription on outpatient basis
- Where
- Kuwait
- Volunteers
- 300 people
- Sponsor
- Cairo University
Body Image, Eating, Healthy
The Effects of Weight Science and Nutrition Education on Weight Control Beliefs and Disordered Eating.
People have different beliefs about controlling their weight. Individuals who believe they should control their weight are more likely to have poor body image, low self-esteem and disordered eating.
- Trial name
- NCT05684263
- Testing
- Weight Science Educational Video, Healthy Eating Educational Video, Healthy Sleep Educational Video
- Volunteers
- 150 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Childhood Obesity, Health-Related Quality of Life
Strong Futures: A Trial of Two Primary Care Based Interventions to Promote Optimal Health in Latino Infants and Toddlers
Latino children experience higher rates of obesity compared to non-Hispanic white children, especially in low-income communities.
- Trial name
- NCT03438721
- Testing
- Infant obesity prevention, Financial coaching
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of California, San Francisco