Clinical trials: Bone Changes
Implant Complication
Modified Shell Technique Versus Onlay Bone Graft in Anterior Maxilla
Amount of bone volume and (width and height): Will be measured using linear measurements from CBCT after 6 month from implant insertion.
- Trial name
- NCT03663439
- Testing
- modified shell technique
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fractures
Evaluation of the Change in Length of the Leg in Children After Treatment of Femur Fractures.
Femur fractures are a common injury in the Pediatric population. Despite their high incidence little do we know about the long term implications on the bones' length.
- Trial name
- NCT00355420
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Osteoporosis
Osteoporosis Prevention: Changes to Exercise and Diet in Children
The purpose of this study is to determine whether educating parents about health and behavior management techniques will increase physical activity, calcium intake, fitness, and bone density in their children.
- Trial name
- NCT00063050
- Testing
- Physical activity and nutrition intervention
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Pectus Excavatum
Quantification of Chest Wall Changes After Nuss Bar Removal Utilizing Three-dimensional Optical Surface Scans
Pectus excavatum is the most common anterior chest wall deformity that affects up to 1:400 of newborns. If an operative correction is indicated, patients are often operated via the Ravitsch or Nuss bar procedure. The latter (i.e.
- Trial name
- CHEST (NCT04052321)
- Testing
- 3D optical surface scan
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Orthopedic Disorder
Evaluation of Architectural Changes in Mandibular Bone Pattern After Functional Treatment by Fractal Dimension Analysis
In this study it was aimed to examine the changes in mandibular bone after functional treatment by using fractal dimension (FD) and cortical thickness (CT) analysis.
- Trial name
- NCT04730115
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Injuries, Genetic Change
Candidate Gene Association Study With Injury in Elite Male Youth Football Players
Understanding how candidate genes, previously associated with injury susceptibility, influence the incidence of muscle, bone, ligament, and tendon injuries across the development pathway of elite footballers may provide valuable…
- Trial name
- NCT04952662
- Testing
- Genetic variants
- Where
- 2 sites in United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Patient Satisfaction
Patient Centered Outcomes and Marginal Bone Changes in CAD/CAM Metallic and (PEEK) Partial Denture Frameworks
To compare PEEK to metallic partial denture frameworks in restoring mandibular Kennedy class I regarding patient satisfaction.
- Trial name
- NCT05622448
- Testing
- RPD with PEEK framework, RPD with metallic framework
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Hydronephrosis, Congenital Choledochal Cyst
Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children
Etomidate is an unique drug used for induction of general anesthesia and sedation. Adrenal cortical inhibition by etomidate has received much attention.
- Conditions
- Congenital Hydronephrosis, Congenital Choledochal Cyst, Fracture
- Trial name
- NCT02013986
- Testing
- etomidate, midazolam, propofol
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Du yi
Bone Sarcoma, Childhood Cancer
Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer
This is a prospective study that will conduct a series of focus groups with non-Hispanic Black and Hispanic childhood cancer survivors to obtain their input on culturally adapting a mobile CBT program for chronic pain and tDCS…
- Trial name
- NCT05746429
- Testing
- Cognitive Behavior Therapy, Transcranial Direct Current Stimulation, Questionnaire Administration
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Osteoporosis
Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study
Osteoporosis affects nearly half of all American women over age 50. During the teenage years, girls can increase bone growth to decrease their risk of osteoporosis later in life.
- Trial name
- NCT00067600
- Testing
- Diet with increased fruits, vegetables, and calcium, Increased high impact activity and resistance training
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infection
Renal, Endocrine, and Bone Changes in Response to FTC/TDF in Uninfected Young Men Who Have Sex With Men (YMSM).
This is a prospective observational cohort sub-study of subjects enrolled in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) 110 (NCT01772823) or ATN 113 (NCT01769456), which is a prospective…
- Trial name
- NCT01769469
- Testing
- FTC/TDF (Truvada®)
- Where
- 12 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Defect of Articular Cartilage, Osteoarthritis
Comparison of Efficacy and Safety of Microfracture and Modified Microfracture
This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture to prove the non-inferiority of the modified microfracture using…
- Conditions
- Defect of Articular Cartilage, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539030
- Testing
- Microfracture, CartiFill
- Where
- 12 sites in South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Leg Length Inequality, Leg; Lengthening
Femoral Lengthening Might Impair Physical Function and Lead to Structural Changes in Adjacent Joints
This study evaluates function, quality of life and development of hip- and knee osteoarthritis minimum 15 years after unilateral femoral lengthening on people with idiopathic or post-traumatic anisomelia.
- Conditions
- Leg Length Inequality, Leg; Lengthening, Osteoarthritis, Knee, Osteoarthritis of Hip
- Trial name
- NCT03966573
- Testing
- Radiographic imaging, Evaluating function, Forms
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Maxillary Constriction in Growing Children, Transverse Maxillary Deficiency
Effects of BREA and MFT Expansion Appliances on Upper Airway Dimensions
This retrospective study evaluated whether orthodontic expansion using two types of appliances, a bimaxillary removable expansion appliance (BREA) and a maxillary fixed three screw palatal expander (MFT), influences upper airway…
- Conditions
- Maxillary Constriction in Growing Children, Transverse Maxillary Deficiency, Upper Airway Morphology in Children, Orthodontic Expansion Effects
- Trial name
- NCT07456917
- Testing
- Maxillary fixed three screw palatal expander (MFT), Bimaxillary removable expansion appliance (BREA)
- Where
- Poland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Pseudohypoparathyroidism Type 1A, Albright Hereditary Osteodystrophy
Energy Expenditure and Body Composition in Pseudohypoparathyroidism 1a
The investigators would like to learn more about the metabolic consequences of pseudohypoparathyroidism type 1a in children, adolescents and adults with this condition.
- Trial name
- NCT01398774
- Where
- United States
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Periodontitis, Adult
Clinical and Radiographic Evaluation of NIPSA Versus M-MIST in Treatment of Intra-osseous Defects
The aim: Clinical and Radiographic Evaluation for intra-osseous defects in stage III periodontitis using NIPSA versus M-MIST Steps in short Pre-surgical therapy Before surgical intervention, each patient will be given careful…
- Trial name
- NCT04149834
- Testing
- Group A (Test): Patients will receive NIPSA, Group B (Control): Patients will receive M-MIST
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Metabolism
Critical Periods of Exercise
Early childhood (~3-7 years of age) is an important window for determining body composition trajectory and may be a critical period for the development of tissue partitioning patterns that influence obesity risk.
- Trial name
- NCT01041820
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Phenylketonuria
Nutritional and Neurotransmitter Changes in PKU Subjects on BH4
HYPOTHESIS: The investigators hypothesize that KuvanTM therapy could influence nutritional and body composition parameters and neurotransmitter concentrations in pediatric and adult PKU subjects.
- Trial name
- BH4&PKU (NCT00688844)
- Testing
- KuvanTM Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Emory University
Contraception, Change in Bone Mineral Density
Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females
This study will be in two parts, Part A and Part B. The primary objective of Part A is to evaluate the contraceptive efficacy of LPRI-CF113.
- Trial name
- NCT05461573
- Testing
- Drospirenone
- Where
- 47 sites in United States, Canada
- Volunteers
- 1,542 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Myeloproliferative Neoplasm
Cardiac Changes in Myeloproliferative Neoplasms
Myeloproliferative neoplasms are heterogeneous group of clonal hematopoietic stem cell neoplasms with excessive proliferation of one or more of the erythroid, megakaryocytic, or myeloid lineages and relatively normal maturation…
- Trial name
- NCT03177928
- Testing
- Transthorathic echocardiogram
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University