Clinical trials: Bone Density
Survivors of Bone Marrow Transplant, Autologous and Allogeneic
Musculoskeletal Outcomes After Bone Marrow Transplant
The purpose of the study is to evaluate bone mineral density and muscle strength in survivors of bone marrow transplant. Association with age, type of transplant, steroids, years since transplant, body composition…
- Trial name
- NCT00558948
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Vitamin D Deficiency
Treatment of Vitamin D Insufficiency
The purpose of this study is to answer the following questions: Does vitamin D increase calcium absorption, bone mass and muscle mass and function in women past menopause who have mildly low vitamin D levels? Do these benefits…
- Trial name
- NCT00933244
- Testing
- High Dose Vitamin D3, Low Dose Vitamin D3
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Bone Development, Dietary Adequacy
Improving Bone Health in Adolescence Through Targeted Behavioral Intervention
School based educational intervention to educate on bone health among Hispanic, Asian or non-Hispanic white girls between 10-13 years with end points of knowledge gained, calcium intake and bone density in .
- Trial name
- NCT02202889
- Testing
- Adequate Calcium Today
- Where
- United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Purdue University
Vitamin D Deficiency, Injuries
Vitamin D Status Among Competitive Female Gymnast and Swimmers After Winter Time
As indoor athletes, competitive gymnasts and swimmers can face the problem of a potential vitamin D deficiency. In the last decades, indoor sports participants have been faced with the problem of an institutionalized lifestyle…
- Conditions
- Vitamin D Deficiency, Injuries, Cardiovascular Risk Factor, Nutritional Deficiency
- Trial name
- NCT03584256
- Where
- Slovenia
- Volunteers
- 31 people
- Sponsor
- University of Ljubljana
Cerebral Palsy, Osteoporosis
Influence of Verticalization on Bone Mineral Density and Biological Parameters of Bone Remodeling in Children With Severe Cerebral Palsy
Low bone mineral density affects 77% of children with severe cerebral palsy (GMFCS IV \& V) with an increased fracture risk of 4%. One strategy supposed to improve bone mineral density is verticalisation with static devices.
- Conditions
- Cerebral Palsy, Osteoporosis, Bone Mineral Density, Bone Remodeling Disorder
- Trial name
- CPABONE (NCT04761666)
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Gastrointestinal Diseases, Colic
Effect of Lactobacillus Reuteri DSM17938 in Neonates Treated With Antibiotics
The aim of the study is to elucidate the relationship between postnatal antibiotic administration on development of gut microbiota and possible protective influence of simultaneously administration of probiotic during antibiotic…
- Trial name
- NCT02865564
- Testing
- Lactobacillus reuteri DSM 17938, ampicillin and gentamicin
- Where
- Slovenia
- Volunteers
- 98 people
- Sponsor
- University Medical Centre Ljubljana
Osteoporosis, Postmenopausal, Bone Density, Low
The Effect of the Probiotic Strains on Bone Mineral Density in Postmenopausal Women
Osteoporosis is a systemic condition characterized by low bone mass and altered bone tissue microarchitecture, with the resulting greater bone fragility leading to fractures.
- Trial name
- NCT06375668
- Testing
- Probiotic
- Where
- 3 sites in Poland
- Volunteers
- 170 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Osteogenesis Imperfecta, Osteoporosis
REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)
This study evaluates bone mineral density (BMD) in pediatric patients aged 5-18 years with conditions negatively affecting bone health, using REMS (Radiofrequency Echographic Multi Spectrometry), a non-invasive and radiation-free…
- Conditions
- Osteogenesis Imperfecta, Osteoporosis, Hypogonadisms, Neoplasia
- Trial name
- NCT07412782
- Testing
- REMS
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Meyer Children's Hospital IRCCS
Vitamin D Deficiency, Cystic Fibrosis
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF
Cystic fibrosis (CF) is an autosomal recessive disease caused by alterations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, characterized by multisystemic alterations, mainly in the lung, intestine…
- Conditions
- Vitamin D Deficiency, Cystic Fibrosis, Bone Density, Low, Inflammation Chronic
- Trial name
- NCT05276960
- Testing
- Cholecalciferol Pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Osteoporosis
A Randomized, Double-blind, Placebo-controlled, Dose Response Study of AMG 162 (Denosumab) in Japanese Postmenopausal Osteoporotic Subjects
The primary objective of this study is to assess the effect of AMG 162 (denosumab) treatment on the lumbar spine BMD at month 12 and safety profile across the dose range tested (14, 60 and 100 mg SC once every 6 months) in…
- Trial name
- NCT00306189
- Testing
- 100 mg AMG 162, 60 mg AMG 162, 14 mg AMG 162
- Volunteers
- 212 people
- Sponsor
- Amgen
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Acute Lymphoblastic Leukemia
Pharmacokinetics of Dexamethasone in Childhood ALL and Reduction in Bone Mineral Density
The goal of this observational study is to learn about systemic and central nervous system (CNS) exposure to dexamethasone in childhood acute lymphoblastic leukaemia (ALL).
- Trial name
- NCT06367725
- Where
- 4 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Precursor Cell Lymphoblastic Leukemia-Lymphoma, Vitamin D Deficiency
Nutrition and Body Composition in Acute Lymphoblastic Leukemia
Many adolescents with acute lymphoblastic leukemia (ALL) have been found to have low bone density by the end of treatment. This can lead to long-term suffering in survivors due to poor bone health.
- Trial name
- NCT01317940
- Testing
- Vitamin D and Calcium Citrate
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Premature Ovarian Failure
Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure
The aim of the study is to determine whether physiological sex steroid replacement improves parameters of skeletal, cardiovascular and reproductive health of women treated with current sex steroid replacement regimens.
- Trial name
- NCT00732693
- Testing
- Ethinylestradiol / Norethisterone, Estradiol / Progesterone
- Where
- 2 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Edinburgh
Osteoporosis
Longitudinal Study of Bone Mineral Density in Survivors of Solid Pediatric Cancers
Specific subgroups of children who survive treatment for childhood malignancies have been shown to develop relative osteopenia following chemotherapy and are felt to be at risk for developing osteoporosis later in life due to…
- Trial name
- NCT00615485
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- State University of New York - Upstate Medical University
Prostatic Neoplasms
Bicalutamide Monotherapy Has Significant Quality of Life Benefits for Men With Advanced Prostate Cancer
The aim of this study is to comprehensively monitor the effects of a nonsteroidal antiandrogen in patients requiring hormone manipulation for prostate cancer
- Trial name
- NCT00551044
- Testing
- Bicalutamide
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Osteoporosis
Changes in Bone Mineral Density and Fracture Risk in Patients Receiving Androgen Deprivation Therapy for Prostate Cancer
The aim of this study is to determine the long term effects of two types of hormonal treatment for advanced prostate cancer (LHRH agonists and the antiandrogen bicalutamide)on the bone mineral density of patients.
- Trial name
- NCT00536653
- Testing
- Bicalutamide and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate) and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate)
- Where
- United Kingdom
- Volunteers
- 618 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Osteopenia Of Prematurity
A Preliminary Study of Bone Density in Neonates
The study is to measure how dense or solid the infant's bones are using a new ultrasound machine and how that density changes over time.
- Trial name
- NCT00631397
- Testing
- Ultrasound machine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Osteopenia, Prematurity
Proton Pump Inhibitor Therapy and Bone Density in Premature Infants
Previous research studies have shown that there may be a connection between proton pump inhibitor therapies and hip fracture in adults(1).
- Trial name
- PPI (NCT00888017)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Fractures
Influence of External Factors on Skeletal Growth in Youth
Objective: Prospective study regulation in bone mass, size, architecture, cortical, trabecular bone, soft tissues and risk factors for cardiovascular disease at growth. Determine regulation by environmental factors.
- Trial name
- NCT00633828
- Testing
- Increased physical education in primary school (daily)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Region Skane