Clinical trials: Bone Density, Low
Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive
Growth, Health and Development in Children Born Extremely Preterm
Background: In a national Norwegian cohort of children born before 28 weeks gestation or with a birth weight less than 1000 g born in 1999 and 2000, 372 survived.
- Conditions
- Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive, Disorder of Bone Density and Structure, Unspecified, Cognition Disorders
- Trial name
- PEP11 (NCT01150071)
- Where
- 2 sites in Norway
- Volunteers
- 232 people
- Sponsor
- University of Bergen
Peri-implantitis
Surgical and Non-surgical Treatment of Peri-implantitis
This study will compare surgical and non surgical treatments of peri-implantitis. Peri-implantitis is an inflammation around dental implants that can lead to the loss of the implant over time if no treatment is established.
- Trial name
- Perio-implants (NCT02241577)
- Testing
- Surgical treatment, Non-surgical treatment
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of Rio Grande do Sul
Reconstruction of Massive Bone Loss (Oncologic and Non-oncologic)
Prospective Evaluation of Adler Laboratory's Massive Prosthetic Implants in Oncological and Non-oncological Situations
Massive prostheses are the standard treatment for extensive bone loss, whether caused by cancer or other factors (complex fractures, multiple revisions, infections).
- Trial name
- IMPULSION (NCT07369778)
- Where
- France
- Volunteers
- 375 people
- Sponsor
- Nantes University Hospital
Low Bone Mass, Low Bone Mineral Density
A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab
To characterize the effects of discontinuation of denosumab therapy on variables of bone histology in postmenopausal women with low bone mass or osteoporosis.
- Conditions
- Low Bone Mass, Low Bone Mineral Density, Osteoporosis, Postmenopausal Osteoporosis
- Trial name
- NCT00887965
- Testing
- Previous denosumab
- Volunteers
- 15 people
- Sponsor
- Amgen
Osteogenesis Imperfecta, Osteoporosis
REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)
This study evaluates bone mineral density (BMD) in pediatric patients aged 5-18 years with conditions negatively affecting bone health, using REMS (Radiofrequency Echographic Multi Spectrometry), a non-invasive and radiation-free…
- Conditions
- Osteogenesis Imperfecta, Osteoporosis, Hypogonadisms, Neoplasia
- Trial name
- NCT07412782
- Testing
- REMS
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Meyer Children's Hospital IRCCS
Osteopenia, Postmenopausal Osteopenia
Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides in Postmenopausal Women With Osteopenia
Osteoporosis is undoubtedly one of the most common diseases affecting older individuals with debilitating consequences. Osteopenia, defined as T-score between -1 and -2.5, has also been associated with increased risk of…
- Trial name
- NCT03999775
- Testing
- Calcium, vitamin D and bioactive collagen peptides supplement, Calcium and vitamin D supplement
- Volunteers
- 51 people
- Sponsor
- Ioannis K. Triantafyllopoulos, MD,MSci,PhD
Crohn's Disease, Nephrotic Syndrome
Glucocorticoid-induced Osteopenia in Children
The purpose of this study is to characterize the skeletal deficits and risk factors for impaired skeletal development in children requiring glucocorticoid therapy.
- Trial name
- NCT00289328
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Alveolar Cleft
Radiographic Evaluation of Secondary Alveolar Bone Grafting in Patients With Alveolar Cleft
Study about the comparison of post-operative results of secondary alveolar grafts according to two age groups: early secondary (4 to 7 years) versus late secondary (8 to 11 years) using a recently proposed score based on…
- Trial name
- SABG (NCT04845308)
- Where
- France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Montpellier
Osteoporosis, Osteoporosis, Postmenopausal
Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation
This two-year observational, open-label clinical trial will evaluate the efficacy of a once-yearly infusion of zoledronic acid after denosumab discontinuation to maintain tissue mineral density and bone microarchitecture using…
- Conditions
- Osteoporosis, Osteoporosis, Postmenopausal, Osteopenia, Bone Loss
- Trial name
- NCT05405894
- Testing
- Zoledronic acid
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Bone Atrophy, Alveolar
Piezo-assisted Expansion of Narrow Ridges
the goal of the study was the evaluation of the clinical and histological performance of delayed inserted implants in augmented sites with a shaped solid graft inserted in an originally narrow alveolar edentulous ridge.
- Trial name
- PRIDE (NCT07401238)
- Testing
- Alveolar Ridge Reconstruction
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Trieste
HIV Infection
Safety and Effectiveness of Alendronate for Bone Mineral Density in HIV-infected Children and Adolescents
HIV-infected children, youth, and adults have lower bone mineral density (BMD) than would be expected for HIV-uninfected people of similar age, weight and race. As the majority of perinatally HIV-infected U.S.
- Trial name
- NCT00921557
- Testing
- Alendronate, Calcium carbonate/vitamin D
- Where
- 10 sites in United States, Brazil and 1 more
- Volunteers
- 52 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Prostate Cancer
PR.7 Companion Trial: Effect of Intermittent Versus Continuous Androgen Suppression on Bone Loss and Body Composition
The purpose of this study is to determine, in patients entered on the National Cancer Institute of Canada (NCIC)-PR.7 trial of intermittent versus continuous androgen ablation, whether the rates of osteoporosis, fractures, and…
- Trial name
- NCT00228124
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Ontario Cancer Research Network
Osteopenia Prematurity
Effect of Assisted Exercise on Musculoskeletal System and Growth in Preterm Infants
The primary aim of this study is to assess whether physical activity programs in preterm infants improve bone mineralization as well as growth and reduce the risk of fractures.
- Trial name
- NCT03354988
- Testing
- Physical exercise group, Control group
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Open tíbia Fracture With Sub-segmental Bone Loss
Calcium Sulfate Spacer in Open Tibia Fractures
Investigators will compare antibiotic impregnated Calcium sulfate versus PMMA versus nothing in these sub-segmental bone defects.
- Trial name
- NCT03042546
- Testing
- Calcium Sulfate, PMMA, No treatment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Washington
Hypophosphataemia, Osteopenia of Prematurity
Investigating a New Way of Giving Medicine to Newborn and Preterm Babies
There is a deficit in the number of 'age-appropriate' formulations available for the delivery of medicines to children. Liquid preparations are considered the 'gold standard' for delivering medicines to children however many of…
- Trial name
- NCT01676844
- Testing
- Oral thin film therapy (Potassium acid phosphate oral thin films), Standard therapy (Potassium acid phosphate oral solution)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Strathclyde
Osteoporosis
Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer
The aim of this study is to determine if 3 monthly infusions of zoledronic acid, given over one year, improves the bone mineral density in osteoporotic patients undergoing androgen deprivation therapy for prostate cancer
- Trial name
- NCT00520052
- Testing
- zoledronic acid
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Alveolar Cleft
Alveolar Cleft Reconstruction With Cortical-Shells
The main goal of the secondary alveolar bone grafting (SABG) for alveolar clefts is the rehabilitation of the disorganized maxilla, aiming to stabilize the maxillary foundation as a solid functional mass that would abort growth…
- Trial name
- NCT06585566
- Testing
- Cortical-shell graft
- Where
- 2 sites in Egypt
- Volunteers
- 7 people
- Sponsor
- Beni-Suef University
Patients With Anorexia Nervosa
Bone Loss in Patients With Anorexia Nervosa
Nutritional deprivation of adolescent girls with anorexia nervosa (AN) reduces the bone mass acquisition. A better understanding of this process would improve the medical treatment of bone alteration and its long-term…
- Trial name
- NCT01907464
- Testing
- clinical parameters description, para clinical parameters description, hormonal parameters dosing
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Osteopenia of Prematurity
Low and High Doses of Prophylactic Vitamin D in Prevention of Osteopenia of Prematurity
In this study the effects of low and high doses of prophylactic vitamin D on biochemical and radiological manifestations of osetopenia of prematurity will be tested.
- Trial name
- NCT04768439
- Testing
- Low Dose Vitamin D, High Dose Vitamin D
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University