Clinical trials: Bone Health
Bone Development, Dietary Adequacy
Improving Bone Health in Adolescence Through Targeted Behavioral Intervention
School based educational intervention to educate on bone health among Hispanic, Asian or non-Hispanic white girls between 10-13 years with end points of knowledge gained, calcium intake and bone density in .
- Trial name
- NCT02202889
- Testing
- Adequate Calcium Today
- Where
- United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Purdue University
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Adolescence Idiopathic Scoliosis, AIS
Smartphone App for Adolescents With Idiopathic Scoliosis
This study aims to evaluate a smartphone application (DinSkoliose) designed to support adolescents with idiopathic scoliosis (AIS) in managing their condition and following their treatment.
- Trial name
- NCT07686848
- Testing
- DinSkoliose smartphone application
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo Metropolitan University
Patient Satisfaction
Patient Centered Outcomes and Marginal Bone Changes in CAD/CAM Metallic and (PEEK) Partial Denture Frameworks
To compare PEEK to metallic partial denture frameworks in restoring mandibular Kennedy class I regarding patient satisfaction.
- Trial name
- NCT05622448
- Testing
- RPD with PEEK framework, RPD with metallic framework
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hematopoietic Cell Transplant
The MedMemos Study: Promoting Adherence to Medications in Pediatric Bone Marrow Transplant Patients
The goal of this clinical trial is to test the MedMemos Intervention with parents and children who have received a bone marrow transplant.
- Trial name
- MedMemos (NCT07718204)
- Testing
- MedMemos
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nationwide Children's Hospital
X-Linked Hypophosphataemia
A UK Multicentre, Health-Related Quality of Life Study for Children and Adolescents With XLH
This study aims to provide Health-related Quality of Life (HRQoL) data from children and adolescents with growing skeletons in the United Kingdom (UK), including those treated with burosumab or alternative XLH treatment, as part…
- Trial name
- NCT04819490
- Where
- 6 sites in United Kingdom
- Volunteers
- 32 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months.
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL, Pediatric Lymphoma, Bone Loss
- Trial name
- HBHL (NCT04472286)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Hypotonia-Cystinuria Syndrome, Muscle Hypotonia
PREPL in Health and Disease
Evaluation of PREPL activity in healthy controls and known or possible PREPL deficient patients
- Conditions
- Hypotonia-Cystinuria Syndrome, Muscle Hypotonia, Healthy Volunteers, Dwarfism, Growth Hormone Deficiency
- Trial name
- PHD (NCT02263781)
- Testing
- Blood draw, muscle biopsy
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
RCDP - Rhizomelic Chondrodysplasia Punctata, RCDP1
Rhizomelic Chondrodysplasia Punctata Registry
The goal of this registry is to collect medical information on individuals with rhizomelic chondrodysplasia punctata and closely related conditions.
- Conditions
- RCDP - Rhizomelic Chondrodysplasia Punctata, RCDP1, RCDP2, RCDP3
- Trial name
- NCT04569162
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nemours Children's Clinic
Ovarian Aging, Adverse Pregnancy Outcomes
The Bone and hEArt Health Consequences of Ovarian agiNg (BEACON) Study
Ovarian aging is a major driver of a woman's long-term health and disease risk. In particular, the rapid decline in the ovarian reserve that occurs with the menopause transition is linked to a striking increase in the risk for…
- Trial name
- BEACON (NCT07621965)
- Volunteers
- 655 people
- Sponsor
- Indiana University
Autism Spectrum Disorder, Bone Health
Oxytocin Effects on Bone in Children With Autism Spectrum Disorder
This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin on bone health in children with autism spectrum disorder, ages 6-18 years old.
- Trial name
- BOX (NCT05754073)
- Testing
- 1. Intranasal oxytocin spray, 3. Intranasal Oxytocin spray
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Elizabeth Austen Lawson
Healthy
Family Milk Product Two-year Dose-response Study to Enhance Bone Health
The final stages in the development of peak bone mass (PBM) reside in late adolescence or early adulthood and are critical in the achievement of bone health.
- Trial name
- FAMILY (NCT02236871)
- Testing
- 2 servings, 4 servings
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- McGill University
Adolescent Idiopathic Scoliosis
Comparing Use of Radiographs Versus Patient Empowerment (CURVE)
Objective: To evaluate the (cost-)effectiveness of a new patient-empowered follow up (FU) protocol in patients with Adolescent idiopathic Scoliosis (AIS) that is based on patient-reported outcome measures (PROMs), self-assessment…
- Trial name
- CURVE (NCT05379127)
- Testing
- Patient-empowered follow up, Standard follow-up
- Where
- 23 sites in Netherlands
- Volunteers
- 812 people
- Sponsor
- Radboud University Medical Center
Osteoporosis, Postmenopausal
Hesperidin and Bone Health in Postmenopausal Women
The primary objective of this clinical trial is to test hesperidin with and without CALCILOCK® for bone resorption suppressing effect in postmenopausal women.
- Trial name
- Hesperidin (NCT01881204)
- Testing
- Hesperidin and Calcilock, Hesperidin, Control
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Purdue University
Anorexia Nervosa
PRE-GAiN Bone Health Pilot Study
This study will assess the affects of an estradiol hemihydrate transdermal system on bone health in 24 adolescent females aged 12-19 years old with anorexia nervosa.
- Trial name
- PRE-GAiN (NCT04021017)
- Testing
- Estradiol Hemihydrate Transdermal System
- Where
- Canada
- Sponsor
- University of Saskatchewan
Edentulism
Patient Satisfaction and Oral Health-Related Quality of Life of Quadrilateral Versus Bilateral Linear Bar Designs for Four Implant Implant-Assisted Complete Mandibular Overdenture Regarding Peri-Implant Crestal Bone Loss
For this study, twenty patients were selected, and participants were randomly divided into two groups using random numbers produced in an Excel spreadsheet.
- Trial name
- NCT06673173
- Testing
- Implant
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Scoliosis, Spinal Curvatures
Preventing Curve Progression and the Need for Bracing in Adolescent Idiopathic Scoliosis With Calcium + Vitamin D Supplementation
There is an association between adolescent idiopathic scoliosis (AIS) and low bone mass which has been reported to be a significant prognostic factor for curve progression.
- Conditions
- Scoliosis, Spinal Curvatures, Spinal Diseases, Bone Health
- Trial name
- NCT03533010
- Testing
- Ca500mg, VitD800IU
- Where
- Hong Kong
- Volunteers
- 199 people
- Sponsor
- Chinese University of Hong Kong
Quality of Life, Bone Neoplasm
Cross Cultural Validation of the Italian Version of the Bt-DUX
The purpose of the presented study is to translate the English Bt-DUX (Bt-DUX-Eng) questionnaire into the Italian language and then examine the validity of the Italian version of the Bt-DUX (Bt-DUX-It).
- Trial name
- NCT04074291
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Istituto Ortopedico Rizzoli
Short Stature, Growth Disorders
Testing the Feasibility of a Novel Growth Monitoring Smartphone App
The goal of this clinical trial is to test the acceptability, feasibility, accuracy and precision of the 'GrowthMonitor' smartphone app in a pilot population.
- Trial name
- NCT05829252
- Where
- United Kingdom
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Scoliosis Idiopathic, Scoliosis; Adolescence
Improving Adherence and Safety of Orthopedic Treatment of Idiopathic Scoliosis in Adolescents Using Information and Communication Technologies
The present project aims to test the feasibility of a new management mechanism for inter-visit monitoring of adolescent patients with idiopathic scoliosis that improves the quality and safety of current orthopedic treatments…
- Conditions
- Scoliosis Idiopathic, Scoliosis; Adolescence, Brace
- Trial name
- NCT04881591
- Testing
- Treatment as usual + APP
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universitat Jaume I