Clinical trials: Bone Level
Recurrent Lumbar Disc Herniation
The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach
What Was the Study About? This study focused on improving the care of patients with a specific type of back problem called lumbar disc herniation at the L5-S1 level.
- Trial name
- NCT06833099
- Testing
- VAS Point and Imaging Examination
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Jinyu Chen
Fitness
Fitness Level in Short Stature Children and After Growth Hormone Treatment
fitness and Physical activity will be evaluate in short stature children, using the Euro Fitness testing and the Wingate anaerobic test.
- Trial name
- NCT02977091
- Testing
- change in fitness level
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Osteoporosis, Hypercholesterolemia
Effect of Atorvastatin on Bone-vascular Axis
Background: Circulating osteoprogenitors and RANKL expression in immune cells have been implicated in the pathogenesis of osteoporosis and vascular calcification.
- Trial name
- NCT02342015
- Testing
- Atorvastatin
- Volunteers
- 20 people
- Sponsor
- University of Padova
Acute Leukemia, Chronic Leukemia
Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell Transplantation
The purpose of this prospective study is evaluate the best dose of busulfan for each patient undergoing Haematopoietic Stem Cell Transplantation
- Conditions
- Acute Leukemia, Chronic Leukemia, Lymphoproliferative Disease, Myeloproliferative Disease
- Trial name
- NCT01800643
- Testing
- Analyze the pharmacokinetics of busulfan for transplantation
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Israelita Albert Einstein
Myelofibrosis
Clinical Trail to Evaluate the Effect of Long-term Treatment With Gecacitinib on Myelofibrosis and Gene Mutation Levels
This study was an observational study, and about 40 patients with intermediate and high risk myelofibrosis who had participated in any previous clinical study of Gecacitinib hydrochloride and were still receiving Gecacitinib…
- Trial name
- NCT07342712
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hematologic Malignancies
Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies
If transplantation using mismatched unrelated donors or non-first-degree relatives could be performed with an acceptable toxicity profile, an important unmet need would be served.
- Trial name
- NCT01203722
- Testing
- Fludarabine, Cytoxan, Total Body Irradiation
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Jaw, Edentulous, Partially, Jaw, Edentulous
Immediate Loading of Implants in the Partially or Completely Edentulous Jaw
The investigators aim to evaluate the biological and mechanical short- and long-term outcome of IL in partially or completely edentulous patients.
- Trial name
- IMLOAD (NCT02661412)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- AZ Sint-Jan AV
Scoliosis
The Effect of Schroth Exercises on Pelvic Floor Muscles
The aim of this study is to evaluate the effect of Schroth exercise training and Traditional Scoliosis exercise training applied 3 days a week for 6 weeks in people with Adolescent Idiopathic Scoliosis on the pelvic floor muscles…
- Trial name
- NCT05637723
- Testing
- schroth exercise, traditional scoliosis exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Bone Involvement in Diseases Classified Elsewhere
Minimally Invasive Lateral Approach for Sinus Augmentation: a Split-mouth Randomized Clinical Trial.
It is assumed that the minimally invasive lateral approach and the traditional lateral sinus lift procedure will result in better outcomes in terms of height of augmented bone.
- Trial name
- NCT02117882
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Firenze and Siena, Napoli, Italy
Osteopenia of Prematurity
The Effect of Daily Exercise Program on Bone Mineral Density and Cortisol Level in Preterm Infants
ABSTRACT Objective: This randomized controlled double-blinded experimental study was carried out to determine the effects of daily exercise program on bone mineral density and cortisol level in preterm infants with very low birth…
- Trial name
- NCT03773679
- Testing
- Daily Exercise
- Volunteers
- 24 people
- Sponsor
- TC Erciyes University
Osgood-Schlatter Disease, Sever's Disease
Low-Level Laser Therapy for Osgood-Schlatter or Sever Pain in Youth Athletes
The goal of this clinical trial is to learn if low-level laser therapy (also called photobiomodulation) works to treat knee or heel pain in physically active children and adolescents with Osgood-Schlatter disease or Sever…
- Trial name
- NCT07446517
- Testing
- Photobiomodulation (Low-Level Laser Therapy)
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Medical University of Gdansk
Scoliosis; Adolescence, Self Esteem
The Relationship Between Body Perception and Self-Esteem Level and Quality of Life in Adolescent Idiopathic Scoliosis
Scoliosis is a three-dimensional, multifactorial disease that becomes more prevalent in adolescents, disrupts the three-dimensional mechanism and posture of the vertebra, causes deterioration in the person's body perception and…
- Conditions
- Scoliosis; Adolescence, Self Esteem, Quality of Life
- Trial name
- NCT06429202
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Halic University
Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia
Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction
Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Phase I trial to study the effectiveness of imatinib mesylate in treating patients who have advanced cancer and liver…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia, AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma
- Trial name
- NCT00025415
- Testing
- imatinib mesylate, pharmacological study
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Vitamin D Deficiency, Rickets
Vitamin D Supplementation in Breastfeeding Women
Adequate vitamin D is essential for proper infant growth and development. However, human milk is low in vitamin D, and most infants do not receive recommended supplementation.
- Conditions
- Vitamin D Deficiency, Rickets, Infant Nutrition Disorders
- Trial name
- NCT01240265
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Post-Traumatic Orbital Deformity
Resorbable Polymer Plates in Repair of Blowout Orbital Floor Fractures
It is a prospective study to evaluate the use of resorbable plates for the repair of blow out orbital floor fractures over a follow up period of one year at both cosmetic and functional levels.
- Trial name
- NCT03683615
- Testing
- repair of orbital floor fractures using resorbable plates
- Volunteers
- 20 people
- Sponsor
- Minia University
Maxillary Hypoplasia
Maxillary Segment Tipping During Transpalatal Distraction
The investigator proposes a multi-centre study to investigate tipping of teeth, bringing into consideration the height of the osteotomy line and the height and placement of the transpalatal distractor as possible factors.
- Trial name
- NCT04041388
- Testing
- Conebeam CT
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Spinal Tumor
The Value of Preoperative Diagnosis and Prognostic Prediction Based on Radiomics of Giant Cell Tumor of Spine
1. Exploit CT (plain scan), enhanced CT and fMRI based radiomic biomarkers, explore their correlation with the prognostic molecular markers of spinal GCTB(p53/vegf/rank/rankl…), and help accurate diagnosis of GCTB. 2.
- Trial name
- NCT04952818
- Testing
- RANK/RANKL(RANK: Receptor Activator of Nuclear factor Kappa-Β /RANKL:Receptor Activator of Nuclear factor Kappa-Β Ligand)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Deproteinized Bovine Bone Mineral Graft Dimensional Changes
Long-term DBBM Dimensional Changes in Sinus Grafting
This study aims to evaluate graft volumetric changes and stability up to 12 years after lateral sinus floor elevation with deproteinized bovine bone mineral (DBBM) as a filling material.
- Trial name
- NCT07635472
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Saint-Joseph University
Laser Therapy, Orthodontic Tooth Movement
Laser Therapy on Orthodontic Tooth Movement
The aims of this study will be to evaluate if a Lower Level Laser Therapy (LLLT): (1) enhances the levels of important pro-inflammatory chemokines involved in the bone remodeling process; (2) increases the rate of orthodontic…
- Conditions
- Laser Therapy, Orthodontic Tooth Movement, Bone Remodeling
- Trial name
- NCT04070170
- Testing
- Low-level Laser Therapy, Orthodontic force
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ildeu Andrade Jr.
Idiopathic Short Stature, Failure to Thrive
Ghrelin Levels in Children With Poor Growth
The investigators hypothesize that low serum ghrelin levels may characterize a group of patients with poor weight gain and/or linear growth who do not have any other identified cause for growth failure.
- Trial name
- NCT01070173
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Tripler Army Medical Center