Clinical trials: Bone Loss, Alveolar
Alveolar Bone Loss
Minimally Invasive Ridge Splitting Versus the Conventional Open Flap Technique
The goal of this clinical trial is to compare implant stability, and crestal bone loss, when using minimal invasive ridge splitting versus convenient open flap technique.
- Trial name
- NCT06329362
- Testing
- Minimally invasive implantation, Open flap procedure for ridge expansion.
- Where
- 2 sites in Egypt, Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Royal College of Surgeons of Edinburgh
Bone Atrophy, Alveolar
Piezo-assisted Expansion of Narrow Ridges
the goal of the study was the evaluation of the clinical and histological performance of delayed inserted implants in augmented sites with a shaped solid graft inserted in an originally narrow alveolar edentulous ridge.
- Trial name
- PRIDE (NCT07401238)
- Testing
- Alveolar Ridge Reconstruction
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Cancer
Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer
RATIONALE: Cyproheptadine hydrochloride may prevent weight loss caused by cancer or cancer treatment. It is not yet known whether cyproheptadine is more effective than a placebo in preventing weight loss in young patients…
- Trial name
- NCT01132547
- Testing
- cyproheptadine hydrochloride
- Where
- 14 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of South Florida
Bone Loss, Alveolar
L-PRF in Alveolar Ridge Preservation
The effect of leucocyte- and platelet-rich fibrin (L-PRF) for enhancing the healing after dental extractions is still a matter of debate.
- Trial name
- L-PRF (NCT03408418)
- Testing
- Platelet-rich fibrin
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Periodontal Disease, Periodontal Bone Loss
Laser Assisted Open Flap Debridement
The study involves the surgical treatment of patients with Stage I to III of periodontitis. Following completion of Steps 1 and 2 of periodontal therapy according to the EFP guidelines for the treatment of periodontitis, sites…
- Trial name
- LaserOpen (NCT07807215)
- Testing
- Mechanical Open Flap debridement, Laser assisted open flap debridement
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Vertical Alveolar Bone Loss
Clinical Evaluation of RTX Locator Attachments for Implant-supported Mandibular Complete Overdenture
This study was conducted to clinically and radiographically evaluate locator RTx attachments for two implant-supported mandibular overdenture using two loading protocols
- Trial name
- NCT05290376
- Testing
- surgical placement of long dental implants, overdenture supported by RTX attachment system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontal Bone Loss
Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the treatment of periodontal intrabony…
- Trial name
- NCT03707483
- Testing
- combination of vitamin C and platelet rich fibrin
- Volunteers
- 20 people
- Sponsor
- Cairo University
Alveolar Cleft
Alveolar Cleft Reconstruction With Cortical-Shells
The main goal of the secondary alveolar bone grafting (SABG) for alveolar clefts is the rehabilitation of the disorganized maxilla, aiming to stabilize the maxillary foundation as a solid functional mass that would abort growth…
- Trial name
- NCT06585566
- Testing
- Cortical-shell graft
- Where
- 2 sites in Egypt
- Volunteers
- 7 people
- Sponsor
- Beni-Suef University
Osteoporosis
Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss
OBJECTIVES: I. Quantify periodontal alveolar bone loss rates in postmenopausal women. II. Evaluate the effects of estrogen on alveolar bone loss rates in these patients. III.
- Trial name
- NCT00004650
- Testing
- conjugated estrogens, Medroxyprogesterone
- Volunteers
- 150 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Alveolar Clefts, Alveolar Bone Grafting
Evaluation of Using Iliac Crest With and Without Platelet-Rich Fibrin in Repair of Congenital Alveolar Cleft
A randomized clinical trial aims to evaluate the clinical and radiographic outcomes of the repair of congenital alveolar clefts using Iliac crest graft with and without mixing with platelet-rich fibrin
- Conditions
- Alveolar Clefts, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- NCT06924216
- Testing
- alveolar bone grafting, alveolar bone grafting Plus Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Suez Canal University
Alveolar Bone Loss
Comparison of Coronally Advanced Lingual Flap to Modified MPI for Flap Advancement in Partially Edentulous Patients
Comparison of cronally advanced lingual flap to modified periosteal releasing incision (MPRI)
- Trial name
- NCT03466840
- Testing
- The coronally advanced lingual flap, Modified periosteal releasing Incision
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillofacial Bone Defect, Alveolar Bone Loss
Bone Marrow Mononuclear Cells for the Repair of Severe Maxillofacial Bone Defects
This is a single-center, single-arm, open-label clinical study conducted at the Department of Stomatology, Nanjing Drum Tower Hospital.
- Trial name
- NCT07852806
- Testing
- Autologous bone marrow-derived mononuclear cells (BMMNCs), Bio-Oss bone graft material with collagen membrane
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Bone Resorption
Using Platelet Rich Plasma in Reducing Alveolar Bone Resorption During Rapid Maxillary Expansion
The purpose of this study is to determine if the injection of Platelet-rich plasma (PRP) is effective in reducing alveolar bone loss that happens after each rapid maxillary expansion (RME) on the buccal aspect of the posterior…
- Trial name
- NCT03028038
- Testing
- Platelet Rich Plasma, No Platelet Rich Plasma
- Where
- Syria
- Volunteers
- 16 people
- Sponsor
- Damascus University
Edentulous; Alveolar Process, Atrophy
Osseodensification Drills Versus Piezoelectric Surgery
implant stability is the first requirement for implant success. the aim is to assess whether different implant site preparation technique may impact the value of the primary stability.
- Trial name
- NCT05410405
- Testing
- implant site preparation
- Where
- 2 sites in Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Peri-implantitis
Surgical and Non-surgical Treatment of Peri-implantitis
This study will compare surgical and non surgical treatments of peri-implantitis. Peri-implantitis is an inflammation around dental implants that can lead to the loss of the implant over time if no treatment is established.
- Trial name
- Perio-implants (NCT02241577)
- Testing
- Surgical treatment, Non-surgical treatment
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of Rio Grande do Sul
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Bone Regeneration, Periodontal Bone Loss
Effect of Nitroglycerin Hydrogel on Repairing Critical Bone Defects
Due to their osteoconductive, osteoinductive, and osteogenic qualities, autologous bone grafts are the gold standard for augmenting bone, (1).
- Conditions
- Bone Regeneration, Periodontal Bone Loss, Healing Fracture of Bone
- Trial name
- Nitro- Bone (NCT06925763)
- Testing
- Nitroglycerin
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Minia University
Periodontal Bone Loss, Periodontitis
The Role of Granulation Tissue in Periodontal Regeneration
The goal of this observational study is to distinguish the infectious, healing, and regeneration-related characteristics of two types of gingival granulation tissues, namely infra-osseous and supra-osseous granulation tissues, in…
- Conditions
- Periodontal Bone Loss, Periodontitis, Periodontal Disease, Periodontal Diseases
- Trial name
- NCT07254117
- Where
- Latvia
- Volunteers
- 34 people
- Sponsor
- Riga Stradins University
Dental Implant Failure, Periodontal Bone Loss
A Retrospective Analysis of Failures of Oral Implants
The purpose of this retrospective study is to investigate and identify factors associated with the failure of dental implants within the population rehabilitated with dental implants at the Folktandvården Specialistklinik in…
- Trial name
- NCT02369562
- Testing
- Evaluation of the failure rate of dental implants
- Where
- Sweden
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Malmö University
Bone Loss, Vertical Alveolar Bone Loss
Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
The purpose of the present research is to evaluate the effect of bioactive glass in bone regeneration immediately following extraction of mandibular and maxillary premolars.The hypothesis of the study assumes that this treatment…
- Conditions
- Bone Loss, Vertical Alveolar Bone Loss, Horizontal Alveolar Bone Loss
- Trial name
- NCT01878084
- Testing
- bioactive glass (sol-gel), empty extraction socket
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University