Clinical trials: Bone Markers
Osteopetrosis
Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5
The aim of the study is to describe patients with a high bone mass phenotype due to a mutation in the low density lipoprotein l receptor 5 gene (LRP5) and compare them with age and sex matched controls.
- Trial name
- NCT01199094
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Asthma
Effect of Different Doses of Budesonide on Markers of Bone Metabolism in Children With Asthma
The purpose of the trial is to check if inhaled glucocorticosteroids (iGCS) have influence on bone condition (if iGCS increases risk of osteoporosis and bone fraction) in children with asthma.
- Trial name
- NCT00487773
- Testing
- budesonide, D3 vitamin, montelukast sodium
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Medical University of Lodz
Sarcoma, Sarcoma, Bone
Exploring the Expression Level of Cadherin 6 Protein (CDH6) in Primary Malignant Bone Tumor Specimens and Its Clinical Application in Prognosis Assessment
1. Evaluate the feasibility of using immunohistochemistry to detect the expression level of CDH6 in histological white slides of patients with osteosarcoma and Ewing's sarcoma as a biological marker for prognostic monitoring The…
- Conditions
- Sarcoma, Sarcoma, Bone, Ewing Sarcoma, Osteosarcoma
- Trial name
- NCT06850506
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University People's Hospital
Bone Turnover Rate Disorder
Bone Turnover and Parenteral Nutrition
Evaluation of changes in biochemical markers of bone metabolism. Fat profile. Evaluation of the overall body development. Assessment of parenteral nutrition protocols.
- Trial name
- NCT03618394
- Testing
- MCT/ω-3-PUFA, Soybean Based
- Where
- Greece
- Volunteers
- 66 people
- Sponsor
- Iaso Maternity Hospital, Athens, Greece
Transplanted Kidney
The Effects of Synbiotic on Cardiovascular and Bone Metabolism Markers in Transplanted Kidney Patients
The aim of this double-blind randomized clinical trial is to determine the effects of synbiotic supplement on cardiovascular disease risk factors and bone metabolism markers and depression, in transplanted kidney patients on…
- Trial name
- NCT06160830
- Testing
- synbiotic
- Volunteers
- 44 people
- Sponsor
- National Nutrition and Food Technology Institute
Osteoporosis
Changes of Bone Metabolic Markers and Bone Mineral Density After Denosumab and/or Teriparatide Treatment in Japanese Osteoporotic Patients
It has not been well known about the changes of bone metabolic markers, bone mineral density and other bone-related markers after teriparatide and/or denosumab treatment in Japanese osteoporotic patients.
- Trial name
- NCT02156960
- Testing
- Denosumab treatment in osteoporotic patients, Teriparatide treatment in osteoporotic patients, Denosumab and teriparatide treatment in osteoporotic patients
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Intestinal Failure, Osteoporosis
Bone Markers in Pediatric IF
Poor bone health is a well-recognized but poorly understood complication in children with intestinal failure (IF) who are dependent on parenteral nutrition (PN).
- Conditions
- Intestinal Failure, Osteoporosis, Metabolic Bone Disease
- Trial name
- NCT05909228
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- The Hospital for Sick Children
Prostate Cancer
TKI258 in Castrate Resistant Prostate Cancer
The goal of this clinical research study is to learn if a decrease in the levels of prostate specific antigen (PSA) may be linked with the status of prostate cancer that has spread to the bones.
- Trial name
- NCT00831792
- Testing
- TK1258
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- M.D. Anderson Cancer Center
Weight Gain, Disorder of Bone Density and Structure, Unspecified
Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects
The investigators are doing this study to look at how different doses of the Depot medroxyprogesterone acetate (DMPA) shot effect weight gain and bone mineral density in teens.
- Conditions
- Weight Gain, Disorder of Bone Density and Structure, Unspecified, Uterine Bleeding
- Trial name
- NCT01461824
- Testing
- Depot medroxyprogesterone acetate (DMPA)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Scoliosis, Adolescent Scoliosis
Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
Inflammatory markers have been analyzed in several diseases of unknown etiology, in the expectation of increasing therapeutic perspectives.
- Trial name
- NCT02413788
- Testing
- aerobic exercise, combined exercise, treadmill
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Coronary Disease
Platelet Activation Markers in Pediatric Cardiac Surgery
In this study the focus will be on correlating the levels of platelet activation markers (proteins that are released when blood cells are activated)to the duration of cardiopulmonary bypass, temperature during cardiopulmonary…
- Trial name
- NCT00450151
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weill Medical College of Cornell University
Calcium, Osteopenia
Effects of Amorphous Calcium Carbonate Supplementation on Bone Health in Postmenopausal Women With Osteopenia
This research was designed in accordance to the Method for Efficacy Assessment of Health Food for Bone Heath. Changes to bone density were measured to evaluate the effectiveness of amorphous calcium carbonate in maintaining bone…
- Conditions
- Calcium, Osteopenia, Bone Mineral Density, Bone Turnover Marker
- Trial name
- NCT05810909
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Bone Health, Performance Enhancing Product Use
Efficacy Comparison of Jarlsberg- and Norvegia Cheese on Bone Markers and Bone Mineral Density in Nordic Skiers
The study objective consists of the following two aims: 1. Compare the effect of daily intake of Jarlsberg and Norvegia cheese on bonehealth in active Cross Country- and Biathlon skiers of both sexes. 2.
- Trial name
- NCT06688032
- Testing
- Jarlsberg cheese, Norvegia
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meddoc
Type 1 Diabetes
Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes…
- Trial name
- NCT05892848
- Testing
- serum ostecalcin,serum sclerostin and parathroid profile
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acromegaly
Surgical Versus Medical Treatment of Acromegaly
Evaluate biochemical differences in acromegalic patients treated with surgery versus somatostatin analogues (SMS) (after surgery or alone). Hypothesis: Treatment modality exhibit different biochemical responses in acromegaly.
- Trial name
- NCT01000090
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Aarhus
Osteoporosis
The Effectiveness of Eldecalcitol in the Bisphosphonate Non-respondered-patients With Osteoporosis
In the patients with osteoporosis, bisphosphonates (BPs) are a golden standard treatment. However, the bone turnover markers or the bone mineral density (BMD) are not improved in some osteoporotic patients even though they have…
- Trial name
- NCT02306187
- Testing
- Edirol
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Osteopenia, Osteoporosis
The Long-term Effect of Daily Jarlsberg Cheese Intake in Patient With Osteopenia
Aim: To estimate the effect of daily optimal efficacy dose (OED) of Jarlsberg cheese in patients with Osteopeni (OP). Study population: Post-menopausal women and men above 55 years of age in risk of Osteoporosis Treatment: Daily…
- Trial name
- PF-JB3 (NCT06358443)
- Testing
- Jarlsberg cheese
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Meddoc
Osteoporosis, Duchenne Muscular Dystrophy
Effects of Low-level Mechanical Vibration on Bone Density in Ambulant Children Affected by Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a X-linked recessive disorder due to a mutation of the dystrophin gene (Xp21). Dystrophin is a sarcolemmal protein of skeletal and cardiac muscle, and its absence causes progressive muscle…
- Trial name
- NCT05281120
- Testing
- Low-level mechanical vibrations WITH vertical sinusoidal acceleration, Low-level mechanical vibrations WITHOUT vertical sinusoidal acceleration
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano