Clinical trials: Bone Turnover Markers
Post Menopausal Osteoporosis
A Study of Ibandronate (Boniva) to Evaluate Bone Turnover Markers in Women With Treatment-Naive Postmenopausal Osteoporosis
This study will evaluate whether an early positive response to once-monthly oral ibandronate in treatment-naive participants with postmenopausal osteoporosis is predictive of efficacy later in treatment.
- Trial name
- NCT02598934
- Testing
- Ibandronate
- Where
- 53 sites in United States, Puerto Rico
- Volunteers
- 308 people
- Sponsor
- Hoffmann-La Roche
Calcium, Osteopenia
Effects of Amorphous Calcium Carbonate Supplementation on Bone Health in Postmenopausal Women With Osteopenia
This research was designed in accordance to the Method for Efficacy Assessment of Health Food for Bone Heath. Changes to bone density were measured to evaluate the effectiveness of amorphous calcium carbonate in maintaining bone…
- Conditions
- Calcium, Osteopenia, Bone Mineral Density, Bone Turnover Marker
- Trial name
- NCT05810909
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Bone Remodeling Disorder, Child Development
Clinical and Genetic Markers of Bone Metabolism in Children Under One Year
The study of children under one year of age for molecular genetic testing-VDR (rs1544410, rs2228570), RANKL (rs9594738, rs9594759) with the study of the frequency distribution of alleles and genotypes by polymorphisms, analysis…
- Conditions
- Bone Remodeling Disorder, Child Development, Genetic Change
- Trial name
- NCT05375331
- Where
- Kazakhstan
- Volunteers
- 245 people
- Sponsor
- West Kazakhstan Medical University
Hip Fracture
Nutritional Risk Factors for Hip Fracture: a Case Control Study
Low Body Mass Index (BMI) is a risk factor for hip fracture, but it is unknown if it is the low BMI per se that increases risk of hip fracture or if specific micro-nutrients contribute.
- Trial name
- NCT01738776
- Where
- Norway
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Type 1 Diabetes
Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes…
- Trial name
- NCT05892848
- Testing
- serum ostecalcin,serum sclerostin and parathroid profile
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Patients With Anorexia Nervosa
Bone Loss in Patients With Anorexia Nervosa
Nutritional deprivation of adolescent girls with anorexia nervosa (AN) reduces the bone mass acquisition. A better understanding of this process would improve the medical treatment of bone alteration and its long-term…
- Trial name
- NCT01907464
- Testing
- clinical parameters description, para clinical parameters description, hormonal parameters dosing
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Vitamin D Deficiency
The Effect of Vitamin D Supplements on Vitamin D Status, Cardiometabolic Health and Immune Defense in Danish Children
The main purpose of this study is to investigate whether and in which doses vitamin D intake is needed in order to maintain an adequate vitamin D status in 4-8 year-old Danish children during wintertime.
- Trial name
- ODIN Junior (NCT02145195)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Disorder of Bone Density and Structure, Unspecified
Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
Adolescents and young adults with anorexia nervosa (AN) are at high risk for low bone mineral density at a time when healthy adolescents are rapidly accruing bone, with implications for peak bone mass and fracture risk in later…
- Trial name
- 814 (NCT00720122)
- Testing
- Recombinant human insulin like growth factor-1 (rhIGF-1)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
Osteoporosis
The Effectiveness of Eldecalcitol in the Bisphosphonate Non-respondered-patients With Osteoporosis
In the patients with osteoporosis, bisphosphonates (BPs) are a golden standard treatment. However, the bone turnover markers or the bone mineral density (BMD) are not improved in some osteoporotic patients even though they have…
- Trial name
- NCT02306187
- Testing
- Edirol
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Bone Turnover Rate Disorder, Calcium Metabolism Disorders
Effects of Lansoprazole on Bone Turnover Markers
Use of proton pump inhibitors (PPI) has increased in recent years. There are concerns that PPIs have possible negative effects on bone metabolism.
- Trial name
- NCT04814316
- Testing
- Blood and urine specimens
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Osteopetrosis
Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5
The aim of the study is to describe patients with a high bone mass phenotype due to a mutation in the low density lipoprotein l receptor 5 gene (LRP5) and compare them with age and sex matched controls.
- Trial name
- NCT01199094
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Intestinal Failure, Osteoporosis
Bone Markers in Pediatric IF
Poor bone health is a well-recognized but poorly understood complication in children with intestinal failure (IF) who are dependent on parenteral nutrition (PN).
- Conditions
- Intestinal Failure, Osteoporosis, Metabolic Bone Disease
- Trial name
- NCT05909228
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- The Hospital for Sick Children
Bone Remodeling, Vitamin D
Bone Turnover Markers and Vitamin D Survey Among Health Professionals in Taiwan
This study will provide the first national overview of BTM and vitamin D utilization among healthcare professionals in Taiwan. The findings are expected to inform educational strategies, optimize clinical implementation, and…
- Trial name
- NCT07387458
- Where
- Taiwan
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Scoliosis, Vitamin D
6 Years Study on Changes in Bone Quality, Bone Turnover and Curve Severity in AIS With and Without Calcium and Vit-D Supplementation
The study aimed to: 1. To investigate and compare the changes in bone mineral density (BMD), trabecular bone micro-architecture, bone strength, and curve severity at a mean of 6 years longitudinal follow up in AIS girls with low…
- Conditions
- Scoliosis, Vitamin D, Bone
- Trial name
- NCT02904421
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Chinese University of Hong Kong
Osteoporosis, Duchenne Muscular Dystrophy
Effects of Low-level Mechanical Vibration on Bone Density in Ambulant Children Affected by Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a X-linked recessive disorder due to a mutation of the dystrophin gene (Xp21). Dystrophin is a sarcolemmal protein of skeletal and cardiac muscle, and its absence causes progressive muscle…
- Trial name
- NCT05281120
- Testing
- Low-level mechanical vibrations WITH vertical sinusoidal acceleration, Low-level mechanical vibrations WITHOUT vertical sinusoidal acceleration
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
Bone Mineral Content, Bone Density
The KOMOtini BONE Study: Evaluation of the Osteogenic Potential of Sports
Bone mass develops throughout childhood and adolescence until a peak bone mass is achieved during early adulthood. Fracture risk later in life can be predicted at a large extent by peak bone mass.
- Conditions
- Bone Mineral Content, Bone Density, Bone Turnover Markers, Athletic Performance
- Trial name
- KOMO-BONE (NCT03201302)
- Testing
- School physical education class, Taekwondo, Martial arts
- Where
- Greece
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Ioannis G. Fatouros
Osteopenia, Postmenopausal Osteopenia
Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides in Postmenopausal Women With Osteopenia
Osteoporosis is undoubtedly one of the most common diseases affecting older individuals with debilitating consequences. Osteopenia, defined as T-score between -1 and -2.5, has also been associated with increased risk of…
- Trial name
- NCT03999775
- Testing
- Calcium, vitamin D and bioactive collagen peptides supplement, Calcium and vitamin D supplement
- Volunteers
- 51 people
- Sponsor
- Ioannis K. Triantafyllopoulos, MD,MSci,PhD
Bone Turnover Rate Disorder
Bone Turnover and Parenteral Nutrition
Evaluation of changes in biochemical markers of bone metabolism. Fat profile. Evaluation of the overall body development. Assessment of parenteral nutrition protocols.
- Trial name
- NCT03618394
- Testing
- MCT/ω-3-PUFA, Soybean Based
- Where
- Greece
- Volunteers
- 66 people
- Sponsor
- Iaso Maternity Hospital, Athens, Greece