Clinical trials: Bowel Dysfunction
Appendicitis
Effect of Pain Control on the Diagnosis of Acute Appendicitis on the Diagnostic Accuracy of General Surgeon
The pain control in surgical abdomen has been in debate in masking the correct diagnosis. We would like to investigate the effect of pain control on the diagnostic accuracy of surgeon in suspicious appendicitis patients.
- Trial name
- NCT00783016
- Testing
- Morphine
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Seoul National University Hospital
Anal Cancer, Nonneoplastic Condition
Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males
RATIONALE: Vaccines made from a gene-modified virus may help the body build an effective immune response to prevent viral infection.
- Conditions
- Anal Cancer, Nonneoplastic Condition, Penile Cancer, Precancerous Condition
- Trial name
- NCT01209325
- Testing
- quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine, laboratory biomarker analysis
- Where
- 19 sites in United States, Puerto Rico
- Volunteers
- 149 people
- Sponsor
- AIDS Malignancy Consortium
Appendicitis
Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds
Acute appendicitis (AA) is the most common condition requiring emergency surgery in children. At a network of institutions nationwide, a tool called the pediatric appendicitis risk calculator (pARC)1 is being studied to assess…
- Trial name
- NCT03522233
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Cholestasis, Prematurity
Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants
Hypothesis to be Tested: Since the first description of intravenous alimentation over half a century ago, parenteral nutrition (PN) has become a common nutritional intervention for conditions characterized by inability to…
- Conditions
- Cholestasis, Prematurity, Gastroschisis, Intestinal Atresia
- Trial name
- NCT01062815
- Testing
- Parenteral Nutrition
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Clostridium Difficile, Inflammatory Bowel Disease
Fecal Microbiome Transplant
Fecal Microbiota Transplant (FMT) in pediatric patients with recurrent C. Difficile with or without Inflammatory Bowel Disease (IBD) The aims of this study are to determine the safety and efficacy of FMT treatment in pediatric…
- Conditions
- Clostridium Difficile, Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT02636517
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Judith Kelsen
Premature Birth, NEC
Prenatal Administration of Spermine Promotes Maturation of Premature Fetal Gut Epithelial Tight Junction: Experimental Study on Fetal Rabbit
Infections, particularly on the gastrointestinal tract, has been known to be one of the leading causes of death in preterm infants. This is due to the immaturity of the intestinal epithelial cells.
- Trial name
- NCT04004091
- Testing
- Spermine
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- dr. Riana Pauline Tamba, SpB(K)BA
Anorectal Malformations, Transition
Transition of Care for Patients With Hirschsprung Disease and Anorectal Malformations
Transition from paediatric to adult health care is crucial for preventing deterioration of chronic diseases. At present, transitional care (TC) is not established for patients with the Hirschsprung disease (H) and Anorectal…
- Conditions
- Anorectal Malformations, Transition, Quality of Life, Hirschsprung Disease
- Trial name
- NOHARM (NCT04106947)
- Testing
- Questionnaires
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Oslo University Hospital
Appendicitis, Gastroenteritis
Study on the Difference of Axilo-rectal Temperature in Appendicitis
The investigators are studying prospectively the difference in axilo-rectal temperature in patients with acute appendicitis and using as a control group patients consulting with acute gastroenteritis at our emergency unit.
- Trial name
- NCT00674726
- Testing
- Observation and measurement of axilo-rectal temperature
- Where
- 2 sites in Chile
- Sponsor
- Cirujanos la Serena
Inflammatory Bowel Disease
Bone Density in Children With IBD Treated With Amorphous Calcium or Commercial Crystalline Calcium
Patients diagnosed with, or in risk of osteoporosis regularly take calcium dietary supplements, although their contribution to BMD maintenance, prevention of bone loss or reduction of the risk of fracture is questionable.
- Trial name
- NCT02470663
- Testing
- DENSITYTM caplets (marketed as Amorphical), Calcium carbonate 600 mg once daily
- Sponsor
- Sheba Medical Center
Anemia
Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO
The investigators seek to determine whether providing inhaled nitric oxide (iNO; a vasodilator) will improve the delivery of oxygen to the brain, kidney and intestines of preterm neonates during and after the subject receives a…
- Trial name
- iNO-TRAGI (NCT02851472)
- Testing
- Inhaled Nitric Oxide
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- New York Medical College
Inflammatory Bowel Disease, Crohn's Disease
Vitamin D Levels in Children With IBD
Research has shown that children with Inflammatory Bowel Disease may have lower levels of vitamin D than healthy children, especially in the winter.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT00621257
- Testing
- ergocalciferol, Cholecalciferol
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Boston Children's Hospital
Helicobacter Pylori Infection
Prevalence and Risk Factors of Helicobacter Pylori Infection in Children and Young Adults
Helicobacter pylori is a gram-negative bacterium that resides in the stomach and can cause inflammation leading to long-term effects, such as gastric ulcers, cancer, and lymphoma of the stomach mucosal linings Previous research…
- Trial name
- NCT05830357
- Where
- Egypt
- Volunteers
- 667 people
- Sponsor
- Sohag University
Breast Cancer, Colorectal Cancer
A Study to Evaluate Avastin in Patients Treated in a Previous Genentech-Sponsored Cancer Study
This is a multicenter, open-label extension study. Subjects who have received rhuMAb VEGF therapy in Study AVF2107g, AVF2119g, or AVF2192g and who completed the parent study are eligible for inclusion in this trial.
- Conditions
- Breast Cancer, Colorectal Cancer, Metastases
- Trial name
- NCT00096967
- Testing
- Avastin (bevacizumab)
- Volunteers
- 100 people
- Sponsor
- Genentech, Inc.
Gastric Ulcer, Duodenal Ulcer
Nexium Capsules Non-steroidal Anti-inflammatory Drug (NSAID) Specific Clinical Experience Investigation
The purpose of this investigation is to collect following data in patients given Nexium capsule (Nexium) for long term in usual-post-marketing therapy to prevention of recurrence of gastric ulcer or duodenal ulcer with…
- Trial name
- NCT01562600
- Where
- 46 sites in Japan
- Volunteers
- 1,634 people
- Sponsor
- AstraZeneca
Celiac Disease in Children, Gluten Enteropathy
Influence of a Gluten Free Food Guide on Diet Quality and Adherence to the GFD in Youth With Celiac Disease
Celiac disease (CD) is an autoimmune gastrointestinal disease that is caused by intolerance to gluten in the diet. The mainstay of treatment is a gluten-free diet (GFD).
- Conditions
- Celiac Disease in Children, Gluten Enteropathy, Diet; Deficiency, Adherence, Treatment
- Trial name
- NCT06038344
- Testing
- Gluten-free food guide teaching
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Pediatric Inflammatory Bowel Disease
Durability and Tolerability of Infliximab in Pediatric Inflammatory Bowel Disease Patients: A 10 Year Single Center Experience
There is little data published on the long term durability of infliximab in pediatric patients. In particular a focus on durable remission, frequency of dose/frequency change and switch within class.
- Trial name
- NCT01490528
- Volunteers
- 200 people
- Sponsor
- Cedars-Sinai Medical Center
Stunting of Growth, Chronic Malnutrition
Pilot Study of a Modified Therapeutic Food Compared With a Standard Nutrient Supplement in Young Children in Rural Guatemala
The goal of this clinical trial is to learn whether a modified food supplement is acceptable and well tolerated by children aged 12 to 24 months with mild-to-moderate stunting in rural Guatemala.
- Trial name
- NCT07804667
- Testing
- Modified Therapeutic Food Formulation, Nutri Listo SQ-LNS
- Where
- Guatemala
- Volunteers
- 36 people
- Sponsor
- Wuqu' Kawoq, Maya Health Alliance
Intestinal Perforation, Necrotizing Enterocolitis
IRT in Infants With Intestinal Perforation
This study is designed to evaluate a novel tool to aid in the diagnosis of intestinal perforation in infants who are at high risk.
- Trial name
- NCT01530828
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Healthy
Safety of Lactobacillus Reuteri in Healthy Children Aged 2-24 Months
Phase I double blinded randomized trial of the safety and tolerability of Lactobacillus reuteri DSM 17938 given for five successive days in healthy children.
- Trial name
- PRIDEC Peru (NCT02460575)
- Testing
- Lactobacillus reuteri 17938
- Where
- Peru
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Small Bowel Disease, Gastrointestinal Diseases
Anonymous Data Sharing for Small Bowel
Crohn's disease is characterised by an abnormal immunological response within the bowel wall leading to abnormal wall thickening, stricturing (narrowing), fistulation (abnormal connections) to adjacent organs and strictures…
- Trial name
- NCT06868875
- Where
- United Kingdom
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University College, London
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