Clinical trials: Brain Damage
Cerebral Palsy
Improvement in Gross Motor Function and Muscle Tone in Children With Cerebral Palsy Related to Neonatal Icterus
The purpose of this study is to evaluate the safety and effectiveness of stem cells for cerebral palsy related to neonatal icterus
- Trial name
- NCT03123562
- Testing
- Stem cell transplantation
- Where
- Vietnam
- Volunteers
- 25 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Cerebral Palsy Spastic Diplegia
Gait Improvement After Increased Frequency of Robot-assisted Gait Training in Cerebral Palsy Children
Robot-assisted gait training (RAGT) can provide a longer training duration with a higher repetition of stepping while maintaining a stable pattern of movement. However, the existing evidence of its effectiveness is not clear.
- Trial name
- NCT05412485
- Testing
- Robotic assisted gait training
- Where
- United Arab Emirates
- Volunteers
- 20 people
- Sponsor
- University of Sharjah
Severe Head Trauma
Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury
This is a randomized, controlled clinical trial at three sites to determine the safety and preliminary efficacy of the study drug to treat severe head trauma (GCS 4-8).
- Trial name
- ABELADRUG200 (NCT00810940)
- Testing
- AbelaDrug200, mannitol
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Abela Pharmaceuticals, Inc.
Cerebral Palsy
Effect of Nordic Walking on Gait-asymmetry Patterns in Children With Hemiparesis
Nordic walking is a physical activity consisting of walking with poles similar to ski poles. The poles are designed for the purpose of activating the upper body during walking.
- Trial name
- NCT05644652
- Testing
- designed physical therapy program, Nordic walking
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Blepharoptosis, Ptosis, Eyelid
Clinical Trial to Improve the Magnetic Levator Prosthesis
Blepharoptosis (incomplete opening of the eyelids) occurs because of a disruption in the normal agonist-antagonist neuro-muscular complex balance. An external device could restore eyelid movement.
- Conditions
- Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis, Stroke
- Trial name
- NCT03818204
- Testing
- Magnetic Levator Prosthesis (MLP)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Concussion, Head Injury Trauma
Detection and Prevention of Concussive Injuries With Smart Technology.
Concussions are consequences of inopportune interactions between an impact force and the head that causes the head (and brain) to move too rapidly. This project involves two parts. 1.
- Trial name
- NCT04946747
- Testing
- Modern microelectrical mechanical systems (MEMS) head-impact sensors, Virtual Reality (VR) Goggle Use with consistent timing of Conditioned Stimulus and Unconditioned Stimulus, Virtual Reality (VR) Goggle Use with inconsistent timing of Conditioned Stimulus and Unconditioned Stimulus
- Volunteers
- 100 people
- Sponsor
- Chi-Ming Huang
Cerebral Palsy
Mobility Exercises for Gait (MEG Neuroplasticity Project)
This study is directed at identifying a the neurophysiological changes seen in children with cerebral palsy (CP) after undergoing physical therapy.
- Trial name
- NCT03555708
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Concussion, Brain
Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion
Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.
- Trial name
- NCT03952208
- Testing
- Neurocognitive Testing
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Brain Injuries, Traumatic, Concussion, Mild
Objective Brain Function Assessment of mTBI/Concussion
This study (Part 3) is designed to build a database including EEG, neurocognitive performance, clinical symptoms, history and other relevant data, which will be used to derive a multimodal EEG based algorithm for the…
- Conditions
- Brain Injuries, Traumatic, Concussion, Mild, Concussion, Intermediate, Concussion, Severe
- Trial name
- CAS13-25 (NCT03963804)
- Testing
- BrainScope Ahead 300iP
- Where
- 4 sites in United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- BrainScope Company, Inc.
Cerebral Palsy
Effects of Hippotherapy on Functionality in Children With Cerebral Palsy
The purpose of this clinical review is to investigate the effect of hippotherapy in improving upper limb functionality in children with cerebral palsy. The main question it aims to answer is The questions are as follows: 1.
- Trial name
- NCT06550258
- Testing
- Equine-assisted therapy, Traditional Pediatric Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Concussion, Mild Traumatic Brain Injury
DHA For The Treatment of Pediatric Concussion Related to Sports Injury
In recent years, media attention has focused on the long-term sequelae of repeated concussive episodes in professional athletes.
- Trial name
- NCT01903525
- Testing
- Docosahexaenoic acid (DHA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Cerebral Palsy
Kinesio Taping in Sit to Stand Movement fo Cerebral Palsy
Children with Cerebral Palsy (CP) present limited performance of functional activities and activities of daily life. Kinesio taping has been definied as a promising technique for children with CP ans has been extensively used in…
- Trial name
- NCT03403322
- Testing
- Kinesio taping, Without taping
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Santa Catarina
Cerebral Palsy (CP), Cerebral Palsy
Dorsal Root Electrical Stimulation in Children With Cerebral Palsy
The goal of this clinical trial is to evaluate whether dorsal root electrical stimulation could reduce spasticity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Cerebral Palsy, Spasticity, Spasticity Due to Cerebral Palsy
- Trial name
- NCT07715006
- Testing
- Constant Current Stimulator, Cadwell Guardian System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Martin Piazza
Cerebral Palsy
Home-based E-biking Intervention Among Individuals With Cerebral Palsy
Investigation of the feasibility of virtually group-based e-biking training at home. Individuals aged 13-60 years with CP (Cerebral Palsy) with a Gross Motor Function Classification System score of 1-3 were recruited for a…
- Trial name
- NCT06402799
- Testing
- Home-based E-biking
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- University of Copenhagen
Cerebral Palsy
Validity and Reliability of the Sitting Assessment Scale in Cerebral Palsy
The Sitting Assessment Scale is a valid and reliable scale that evaluates sitting balance in Cerebral Palsy (CP). The validity and reliability study of the scale has been done, but it has not been adapted to Turkish language.
- Trial name
- NCT05621135
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gaziantep Islam Science and Technology University
Spasticity, Dystonia
The Effects of Cannabis on Dystonia and Spasticity on Pediatric Patients
A clinical trial is planned to study the effects of cannabis on dystonia and spasticity in children with neurological diseases. The clinical trial will include 40 children divided into two groups: children with spasticity and…
- Trial name
- NCT02470325
- Testing
- Avidekel oil, Enriched Avidekel oil
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Wolfson Medical Center
Neuromuscular Diseases, Cerebral Palsy
Effects of Power Wheelchair Soccer for Individuals Presenting With Physical Impairments
This study is a prospective interventional study. It will be conducted at a single center with participants who have neuromotor impairments.
- Trial name
- chair-soccer (NCT06259643)
- Testing
- Power wheelchair soccer
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
Cerebral Palsy, Balance
The Relationship of Forward and Backward Walking with SMC, Trunk Control and Balance in Children with Cerebral Palsy
Children aged between 6-18 years old, diagnosed with cerebral palsy and meeting the inclusion criteria, will be included in this study.
- Conditions
- Cerebral Palsy, Balance, Gait Disorders in Children
- Trial name
- NCT05962749
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Alanya Alaaddin Keykubat University
Concussion, Mild
Omega-3 Treatment for Concussion in Adolescents
The goal of this clinical trial is to test omega-3 fatty acid supplementation as a treatment in adolescents with a concussion. The main questions it aims to answer are: Does supplementing with omega-3 fatty acids improve time to…
- Trial name
- CONCUSS (NCT05847608)
- Testing
- Omega-3
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of Manitoba