Clinical trials: Brain Health
Cardiovascular Diseases, Heart Diseases
Minnesota Heart Health Program
To conduct a large-scale community-based demonstration and education research project designed to evaluate the effectiveness of multiple educational strategies on risk factor reduction and the primary prevention of…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- NCT00005150
- Sponsor
- University of Minnesota
Dementia, Alzheimer Disease
Telehealth Education Program for Caregivers of Veterans With Dementia
This study was designed to evaluate the impact of a Telehealth Education Program (TEP) on outpatient veterans with moderate to severe dementia and their spouse caregivers.
- Trial name
- NCT00105638
- Testing
- educational program, by telephone
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- US Department of Veterans Affairs
Cerebral Palsy (CP), Pain
EFFECTS OF AROMATHERAPY AND REFLEXOLOGY ON PAIN, SLEEP, AND SATISFACTION IN CHILDREN WITH CEREBRAL PALSY
This randomized controlled trial was conducted to evaluate the effects of aromatherapy and foot reflexology on pain, sleep quality, and parental satisfaction in children with cerebral palsy.
- Conditions
- Cerebral Palsy (CP), Pain, Sleep Disorder (Disorder)
- Trial name
- AROMA-REF CP (NCT07519291)
- Testing
- Aromatherapy, Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hakkari Universitesi
Healthy Adolescents
Activity Breaks for Brain Health in Adolescents
The main aim for this study is to investigate to what extent physical activity of moderate or low intensity, relative to prolonged inactivity, may acutely alter neural activity-related prefrontal cortex oxygenated hemoglobin…
- Trial name
- ABBaH teens (NCT04552626)
- Testing
- Prolonged sitting (social breaks), Prolonged sitting with step-up exercise break, Prolonged sitting with simple resistance activity breaks
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Stage IV Breast Cancer, Stage IV Pancreatic Cancer
Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients
This study evaluates the change of quality of life, treatment decision and utilization of health care depending on the use of palliative care in advanced cancer patients by a prospective cohort study.
- Conditions
- Stage IV Breast Cancer, Stage IV Pancreatic Cancer, Stage IV Colon Cancer, Stage IV Gastric Cancer
- Trial name
- NCT03222258
- Testing
- Early palliative care, Routine hospice care
- Where
- 15 sites in South Korea
- Volunteers
- 444 people
- Sponsor
- Seoul National University Hospital
Epilepsy; Seizure
Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking
The goal of this interventional study is to develop a personalized seizure risk forecast tool in people with epilepsy. The main questions it aims to answer are: can we develop a future seizure probabilities tool that is more…
- Trial name
- Foresight (NCT06275685)
- Testing
- SeizureWise algorithm, Multi-day Visualizations
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Empatica, Inc.
Homocystinuria
Health Related Quality of Life (HrQoL) in Classical Homocystinuria (CBS Deficiency)
Patients, parents of young / handicapped patients, and experts will be interviewed to collect contents relevant for HrQoL in CBS deficiency.
- Trial name
- CBS_HrQoL (NCT06556615)
- Testing
- Interview
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University Children's Hospital, Zurich
Stroke, Relatives
Survey of Lifelong Food and Nutrition Assistance (LIFANA) in Stroke Patients and Caregivers
Many elderly suffer from nutritional problems that can cause (or can be caused by) a number of complications such as weakened immune systems and chronic health conditions (diabetes type 2, high blood pressure, cardiovascular…
- Conditions
- Stroke, Relatives, Diet Modification
- Trial name
- NCT03635476
- Testing
- Qualitative interview study
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Cereneo AG
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Traumatic Brain Injury
Transforming Research and Clinical Knowledge in TBI Pilot
The global aim of this proposal is to test and refine Common Data Elements (CDEs), neuroimaging standards, and best practices for genetics and proteomics in Traumatic Brain Injury (TBI) studies.
- Trial name
- NCT01565551
- Testing
- N/A (Observational Study)
- Where
- 4 sites in United States
- Volunteers
- 650 people
- Sponsor
- University of California, San Francisco
Cognitive Ability, General, Achievement
Enhancing Children's Cognitive and Brain Health Through Physical Activity Training (FITKids2)
The objective of this study is to use a randomized controlled design to determine whether cardiorespiratory fitness training improves neurocognitive function and academic performance during preadolescent development.
- Trial name
- FITKids2 (NCT01619826)
- Testing
- Physical Activity
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cerebral Palsy
Pilot Study on Breathing Exercises and Pulmonary Function in Children With Cerebral Palsy: A Randomized Trial
This pilot study is a randomized controlled trial aimed at investigating the efficacy of protocolized conductive breathing exercises combined with regular air ventilation, in addition to standard care, on various aspects of…
- Trial name
- NCT06840626
- Testing
- Series of breathing exercises
- Where
- Hungary
- Volunteers
- 55 people
- Sponsor
- Semmelweis University
Cerebral Palsy, Melatonin
Melatonin for Cerebral Palsy Children's Sleep and Health
The present study was prospective uncontrolled, single-armed and un-blinded study. Held in the Pediatric neurology clinic, Children's hospital l, Faculty of Medicine, Ain Shams University from June 2016 to June 2018 of 24 months…
- Conditions
- Cerebral Palsy, Melatonin, Growth, Children, Only
- Trial name
- NCT04392063
- Testing
- Melatonin 3 mg
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Children, Adolescents
Exercise and Endocannabinoids for Brain and Mental Health
This study will explore how exercise affects brain chemicals called endocannabinoids, which may improve thinking skills and reduce feelings of stress, anxiety, and low mood in children and teens aged 9 to 17.
- Trial name
- EMBH (NCT06808490)
- Testing
- Moderate Intensity Exercise, Light Intensity Stretching, Seated Meditation
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Screen-use Reduction + Sleep Extension, Free-living
Personalising Children's Screen Use Reduction for Better Sleep, Mental, and Brain Health
In Singapore, 64.4% of school-age children sleep less than the minimum recommended duration of 9 hours on school nights, thus risking poor mental, cognitive, and brain health.
- Trial name
- NCT05956392
- Testing
- Screen-use reduction + Sleep extension
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Cerebral Palsy, Spina Bifida
Virtual Peer Health Coaching for Adolescents With Disabilities
Participation in physical activity (PA) confers clear physical and psychosocial benefits. Yet, many adolescents with physical disabilities such as cerebral palsy and spina bifida do not engage in regular PA, putting them at…
- Trial name
- NCT05587634
- Testing
- Virtual Peer Health Coaching
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke, Nursing Caries
The Effect of Health Promotion Training on Life Qualities and Self-Care Powers in Stroke Patients
There are many methods that nurses use while providing care education to individuals. Tele-nursing, which is one of the current methods, is an innovative approach, but it is a useful method in meeting the post-discharge home care…
- Conditions
- Stroke, Nursing Caries, Quality of Life, Self-care
- Trial name
- NCT05484843
- Testing
- telenursing training based on self-care theory, just observation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University
Dementia, Alzheimer Disease
Assessing a Novel Virtual Environment That Assists With Activities of Daily Living
This Phase 1 study looks at how a new videogame-based program can help residents and care partners prepare for ADLs in a fun way with minimal risk, potentially reducing escalating problems associated with ADL completions.
- Conditions
- Dementia, Alzheimer Disease, Neurodegenerative Diseases
- Trial name
- NCT05418296
- Testing
- A novel digital health device
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- mandy
Epilepsy
Epilepsy Adherence in Children and Technology (eACT)
Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life, and high healthcare costs.
- Trial name
- eACT (NCT03817229)
- Testing
- Education microlearning sessions, Automated digital reminders, Problem-solving mHealth module
- Where
- 4 sites in United States
- Volunteers
- 268 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
HIV/AIDS, Hypertension
Evaluating the Impact of a Community Health Worker Program in Neno, Malawi
This protocol concerns the implementation and evaluation of an intervention designed to realign the existing cadre of Community Health Workers (CHW) in Neno District, Malawi to better support the care needs of the clients they…
- Conditions
- HIV/AIDS, Hypertension, Asthma, Diabetes
- Trial name
- NCT03106727
- Testing
- Household model
- Where
- Malawi
- Volunteers
- 122,395 people, healthy volunteers welcome
- Sponsor
- Partners in Health