Clinical trials: Brain Injury
Posttraumatic Stress Disorder
Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Chronic Posttraumatic Stress Disorder (PTSD)
Posttraumatic stress disorder occurs in patients who have experienced, witnessed or have been confronted with an event involving actual death or the threat of death, serious injury, or the threat to physical health and felt fear…
- Trial name
- NCT00001657
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Mental Health (NIMH)
Head Injury, Intracerebral Hemorrhage
The Prediction of Intracranial Pressure and Clinical Outcome by Transcranial Doppler in Neurocritical Patients
The purpose of this study is to use transcranial Doppler (TCD) to predict intracranial pressure (ICP) and clinical outcome of neurocritical patients.
- Conditions
- Head Injury, Intracerebral Hemorrhage, Ischemic Stroke, Subarachnoid Hemorrhage
- Trial name
- NCT00886054
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy, Cerebral Palsy, Spastic
Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy
Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations.
- Trial name
- HABIT-ILE (NCT07253857)
- Testing
- GROUP -A , Hand and Arm Bimanual Intensive Therapy Including Lower Extremity, GROUP-B , Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Traumatic Brain Injury
Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among teens who have had a traumatic brain injury…
- Trial name
- RRTC--TOPS (NCT01042899)
- Testing
- Teen Online Problem Solving (TOPS), Teen Online Problem Solving--Teen Only (TOPS-TO), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 153 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
Efficacy of New Protocols in the Treatment of Upper Limb Dysfunctions in Patients With Cerebral Palsy
Cerebral palsy (CP) is the most common childhood motor disability. Weakness, spasticity, and loss of dexterity are the major problems in patients with CP.
- Trial name
- NCT02039284
- Testing
- SES, VCT, VRCIT
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebral Palsy
G-CSF and Autologous Cord Blood Infusion in Cerebral Palsy
This study is performed to reveal the safety and feasibility of combination therapy with autologous cord blood mononuclear cells (CB) and G-CSF as well as repeated administration of G-CSF for children with cerebral palsy.
- Trial name
- NCT02866331
- Testing
- G-CSF (Leucostim), CB (autologous cord blood)
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Hanyang University Seoul Hospital
Cerebral Palsy
Investigation of Relations Between Edinburgh Visual Gait Score and Selective Motor Control for Children With CP
Children with Cerebral Palsy have generally limited selective motor control which affects their ability to complete functional tasks Selective Motor Control has been shown to correlate with specific characteristics of gait…
- Trial name
- NCT04686630
- Testing
- Video based observational gait analysis and SCALE Test
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Yeditepe University
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Parkinson Disease, Dystonia
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
This study will determine if posture and heart rate variability will significantly improve in Parkinsons disease with camptocormia after osteopathic manual treatments dystonia.
- Conditions
- Parkinson Disease, Dystonia, Autonomic Dysreflexia
- Trial name
- NCT03307161
- Testing
- osteopathic manual therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Cerebral Palsy
Case Series_Targeted Training for Trunk Control Cerebral Palsy
Little is known about how children with cerebral palsy (CP) use their sensory systems (touch, sense of body position, balance organs in the inner ear, vision) to help them achieve trunk control for independent sitting.
- Trial name
- CP_TT_UHart (NCT02246751)
- Testing
- Targeted Training for trunk control
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Hartford
Cerebral Hemorrhage
Retrospective Study on the Direction of Artificial Intelligence in Identifying Cranial Trauma CT Imaging
The goal of this observational retrospective study is to evaluate artificial intelligences (AI)'s proficiency in identifying and annotating brain bleeds in computed tomography (CT) images.
- Trial name
- NCT06230419
- Where
- China
- Volunteers
- 208 people
- Sponsor
- RenJi Hospital
Cerebral Palsy
Motor Disability of Children With Cerebral Palsy Using Motor Transcranial Magnetic Stimulation
Transcranial magnetic stimulation (TMS) has opened new potential avenues for the treatment of neuropsychiatric diseases via the effects of modulation on neuroplasticity.
- Trial name
- NCT02518867
- Testing
- high intensity iTBS, low intensity iTBS
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Brain Damage, Cerebral Palsy
Efficacy of Modified Constraint-induced Movement Therapy in Children With Brain Damage
This research centers on the comparison of the immediate efficacy (right after therapy) and the maintained efficacy (3 months and 6 months) between "Modified Constraint-Induced Movement Therapy" (mCIMT) group and control group at…
- Conditions
- Brain Damage, Cerebral Palsy, Traumatic Brain Damage
- Trial name
- NCT01076257
- Testing
- Modified Constraint-induced Movement Therapy
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Persons With Frontal Lobe Damage With no Specific Language Disorder
Evaluation of Mental Flexibility Through Language Tests in Adolescents With Frontal Brain Damage and in Healthy Children in Ages 8-17
This study aims to shed light on the theoretical concept of mental flexibility and its manifestation in adolescents following frontal lobe damage, and to develop a test battery for young Hebrew speakers.
- Trial name
- NCT01696292
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Cerebral Palsy (CP)
Expiratory Muscle Training in Children With Cerebral Palsy
This study aims to examine the effects of expiratory muscle training on posture, trunk control, balance, selective motor control, and respiratory function in children with spastic-type cerebral palsy (CP).
- Trial name
- CP-EMT (NCT07048223)
- Testing
- Expiratory Muscle Training
- Volunteers
- 20 people
- Sponsor
- Istinye University
Cerebral Palsy
Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for the Treatment of Cerebral Palsy
This is an Individual Patient Expanded Access Protocol of Autologous HB-adMSCs for the Treatment of Cerebral Palsy (CP) with the primary goal of treating 1 individual with CP who has exhausted all treatment options, his condition…
- Trial name
- NCT04029896
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Cerebral Palsy, Dystonia
Whole Body Vibration for Dystonia Cerebral Palsy
Health bones allow us to move and walk freely without pain. Physical activities have been shown to relate to healthy bone growth.
- Trial name
- WBVT (NCT03779308)
- Testing
- whole body vibration therapy
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The Hong Kong Polytechnic University
Cerebral Palsy
Which Taping Technique is More Effective on Balance Skills in Children With Mildly Affected Cerebral Palsy?
"Our study aims to determine which of ankle correction, quadriceps facilitation, and gluteus maximus facilitation taping provides a better immediate effect on balance skills in children with mildly affected cerebral palsy.
- Trial name
- NCT06231108
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy
Brain Change After Fun, Athletic, Sports-skill Training (BeFAST)
The purpose of this study is to determine the associations between changes in neural activity and structure, advanced gross motor skills, gait characteristics, and physical activity participation following a gait-related…
- Trial name
- BeFAST (NCT02584491)
- Testing
- Functional gait-related training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy Spastic Diplegia
Effects of Dynamic Surface Exercise Training on Trunk Control and Gross Motor Functions in Children With Diplegic Cerebral Palsy
The purpose of this study was to determine the effect of dynamic surface exercise treatment on trunk control and gross motor abilities in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05946096
- Testing
- Dynamic surface exercise training, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Ayesha Hameed