Clinical trials: Brain Waves
Spasticity Due to Cerebral Palsy, Spasticity Post-Traumatic Brain Injury
Radial Shockwave for Spasticity in Children With CP or ABI
The goal of this clinical trial is to determine if radial Extracorporeal shockwave therapy (rESWT) reduces spasticity in children with Cerbral Palsy (CP) or traumatic brain injury (TBI).
- Trial name
- NCT06909838
- Testing
- radial Extracorporeal shockwave therapy (rESWT), Conventional treatment
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Gymna Uniphy
Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder
This study tests whether enhancing deep sleep with gentle sounds at night can slow progression in people with iRBD or early Parkinson's disease. Participants wear a sensor headband and headphones for 18 months.
- Trial name
- SloW-iRBD (NCT07355842)
- Testing
- Tosoo Axora
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Periventricular Leukomalacia
Telerehabilitation of Working Memory in Children With Periventricular Leukomalacia and Bilateral Cerebral Palsy
Periventricular Leukomalacia (PVL) is a white matter lesion surrounding the lateral ventricles of the brain occurring in the prenatal period, associated with a disorder of movement and posture, known as bilateral cerebral palsy.
- Trial name
- NCT02342990
- Testing
- Cluster B CogMed: an home-based and computer-based solution to improve working memory deficit, Cluster A No training. Delay start of CogMed
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Fondazione Stella Maris
Auditory Brainstem Response
Comparative Effects of Two Anesthetic Techniques on Auditory Brain Response in Children
This will be a prospective, blinded, cross-over study to compare the effects of two anesthetic techniques on the interpretability of auditory brainstem response testing in children.
- Trial name
- NCT02830815
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Spasticity/Paresis, Cerebral Palsy
Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy
Spastic plantar and palmar flexion deformities are very common in children with cerebral palsy (CP). These deformities usually involve spasticity of the plantar or palmar muscle complexes, weakness of the antagonist dorsiflexor…
- Trial name
- NCT06128616
- Testing
- ESWT, Botulinum Toxin Type A, Serial Casting
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Muscle Spasticity, Cerebral Palsy
Radial Extracorporeal Shock Wave Therapy for Spastic Plantar Flexor Muscles in Young Children With Cerebral Palsy
The purpose of this study is to determine whether radial extracorporeal shock wave therapy in combination with traditional physical therapy is safe and effective for the management of spastic plantar flexor muscles in patients…
- Trial name
- NCT02719483
- Testing
- Swiss DolorClast, Traditional conservative therapy
- Volunteers
- 66 people
- Sponsor
- The First Hospital of Jilin University
Concussion Post Syndrome
Auditory Slow Wave Enhancement After Concussion
The prevalence of a traumatic brain injury (TBI) in children and adolescents is around 30% with 70-90% being classified as mild (concussion).
- Trial name
- NCT04770116
- Testing
- Auditory Stimulation
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Bradycardia, Strabismus
Oculocardiac Reflex Brain Wave Monitor
Oculocardiac reflex during routine strabismus surgery was prospectively observed in association with routine brain wave monitoring.
- Trial name
- OCRBIS (NCT03663413)
- Testing
- non-invasive monitor
- Volunteers
- 188 people
- Sponsor
- Alaska Blind Child Discovery
Spinal Cord Injuries (SCI), Spinal Cord Injury
Clinical Testing of Invasive Spinal Cord Stimulation and Evaluation of Its Physiological Effects Using the Electroencephalography
The aim of the study is to identify the specific characteristics of brain network dysfunctions and assess the recovery of their functionality through the recording of resting-state electroencephalography (EEG) during…
- Trial name
- NCT06725836
- Testing
- Implantation of electrodes into the epidural space for spinal cord stimulation, Selection of the optimal spinal cord stimulation program for spastic syndrome suppression, Selection of the optimal spinal cord stimulation program for volitional motor control
- Where
- 3 sites in Russia
- Volunteers
- 35 people
- Sponsor
- Artur Biktimirov
Athletes
Brain Wave Entrainment Using Alpha Frequency Binaural Beats on Adolescent Swimmers
Relaxation techniques and binaural beats added to music have a positive effect on athletic performance of swimmers than music therapy and mental training alone
- Trial name
- NCT06619470
- Testing
- binaural beats
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Spasticity, Cerebral Palsy
Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT
Spasticity is a motor disorder that can affect the lower limbs in up to 75% patients with cerebral palsy, having a significantly effect on their mobility and quality of life.
- Trial name
- NCT02400619
- Testing
- shock waves, Botulinum Toxin Type A
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Xavi Vidal Novellas
Children With Cerebral Palsy
Extracorporeal Shock Wave Therapy Versus Functional Electrical Stimulation on Spasticity, Function and Gait Parameters in Hemiplegic Cerebral Palsy
Objective: The purpose of this study will compare the effects of extracorporeal shock wave therapy (ESWT) versus functional electrical stimulation (FES) on spasticity, function and gait parameters in hemiplegic cerebral palsy…
- Trial name
- NCT03856905
- Testing
- Physical therapy program, Extracorporeal shock wave therapy, Functional electrical stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Muscle Spasticity, Gait Disorders, Neurologic
Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy
This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities.
- Conditions
- Muscle Spasticity, Gait Disorders, Neurologic, Cerebral Palsy, Spastic
- Trial name
- US-sCP (NCT07118228)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kocaeli University
Stroke
Reliability and Validity of the Vicorder Device When Measuring Pulse Wave Velocity Within Chronic Stroke Patients
Stroke is a major global health problem and main cause of disability worldwide. Blood pressure control is important for good health in stroke patients.
- Trial name
- NCT04342143
- Testing
- Blood pressure and ultrasound assessment
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Winchester
Epileptic Encephalopathy
Cannabidiol in Children With Refractory Epileptic Encephalopathy
This study will assess the safety and tolerability of a cannabidiol-enriched Cannabis Herbal Extract in a small group of children with refractory epileptic encephalopathy.
- Trial name
- CARE-E (NCT03024827)
- Testing
- CanniMed® 1:20
- Where
- 4 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Saskatchewan
Benzodiazepine
Effect of Remimazolam Use During Perioperative Period on Brain Waves and Postoperative Cognitive Function
Benzodiazepine sedative hypnotics are commonly used intravenous anesthetics in clinical practice. Remimazolam is a new benzodiazepine with the characteristics of rapid onset, short maintenance and recovery time, no accumulation…
- Trial name
- NCT04601350
- Testing
- remimazolam group was induced with remimazolam 0.1 mg/kg followed by a maintenance dose of 0.1 mg·kg-1·h-1 for general anesthesia, control group was induced with midazolam 0.05 mg/kg followed by normal saline maintenance of 0.1 ml·kg-1·h-1
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yangzhou University
Wave Form Signals Coming From the Eye in a Healthy Cohort
Neuro-ocular Baselines in a Sports Setting
Rebion (Rebiscan, Inc) has developed a noninvasive, handheld device that uses retinal birefringence scanning (RBS) to rapidly assess eye fixation and retinal integrity in adults and children.
- Trial name
- KY (NCT03653936)
- Testing
- HITT device
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Hemiplegic Cerebral Palsy
Effect of Extracorporeal Shock Wave and Peripheral Magnetic Stimulation on Spastic CP Children
Hypotheses: There will be an effect of radial extracorporeal shock wave therapy and peripheral magnetic stimulation on the following parameters, in children with spastic hemiplegia: Wrist flexors spasticity.
- Trial name
- NCT05607134
- Testing
- selected physical and occupational therapy program, Radial Extracorporeal Shock Wave, Peripheral magnetic stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Rolandic Epilepsy, Nocturnal Frontal Lobe Epilepsy
The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study
In clinical practice language impairment is frequently reported in association with nocturnal epileptiform activity. There is a spectrum of epileptic conditions that are characterized by nocturnal epileptiform activity.
- Conditions
- Rolandic Epilepsy, Nocturnal Frontal Lobe Epilepsy, Landau-Kleffner Syndrome, Electrical Status Epilepticus During Slow Wave Sleep
- Trial name
- REL (NCT01335425)
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Spastic Diplegia Cerebral Palsy
Comparative Effects of Under Water Exercise and Radial Extracorporeal Shockwave Therapy on Lower-Limb Spasticity, Gross Motor Function, and Quality of Life in Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial
Children with spastic diplegic cerebral palsy often present with lower-limb spasticity, limited gross motor function, and reduced quality of life.
- Trial name
- spastic CP (NCT07878949)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Emad Eldin Mohamed