Clinical trials: Breast Cancer Surgery
Breast Cancer
Lymph Node Radiation Therapy in Patients With Stage I, Stage II, or Stage III Breast Cancer That Has Been Surgically Removed
RATIONALE: Radiation therapy may kill any tumor cells remaining after surgery. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared to no further therapy in treating women with…
- Trial name
- NCT00002851
- Testing
- adjuvant therapy, low-LET electron therapy, low-LET photon therapy
- Where
- 48 sites in Belgium, Bosnia and Herzegovina and 12 more
- Volunteers
- 4,000 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Postoperative Pain
Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery
We hypothesize that pregabalin will decrease postoperative pain, as measured by the surrogate markers postoperative pain rating scores and postoperative opioid consumption while improving the quality of recovery following breast…
- Trial name
- NCT00785382
- Testing
- Pregabalin 150 mg
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Breast Cancer
Accessory Joint and Neural Mobilizations in Shoulder After Breast Cancer Surgery. Randomized Clinical Trial.
The potential consequences after breast cancer surgery are joint pain and sensitive disorders, the main sign of which is alterations in shoulder mobility.
- Trial name
- NCT02366793
- Testing
- Accessory joint mobilization, Nerve mobilization
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Breast Cancer, Breast Reconstruction
Incorporating Robotic Surgery in Both Mastectomy and DIEP Flap Reconstruction
A prospective study will be conducted to assess the outcomes of patients who underwent concurrent robotic-assisted mastectomy and robotic-assisted free DIEP flap harvest for breast reconstruction between March 2020 and June 25…
- Trial name
- NCT05945914
- Testing
- Oncoplastic Entirely Robot-Assisted Approach (OPERA)
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Radiation Dermatitis
A DB Randomized Study of R1 and R2 WaterJel / AloeVera Jell in Prevention of Radiation Dermatitis in Breast Cancer
The purpose of this study is to evaluate the effects of topical R1 and R2 for prophylaxis of acute radiation dermatitis in patients with breast cancer receiving radiotherapy.
- Conditions
- Breast Cancer, Radiation Dermatitis, Erythema
- Trial name
- NCT01597921
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Water-Jel
Breast Cancer, Mobility Limitation
Breast: Recovery After Axillary Node Clearance - Evaluating Limbs With E-Technology (the BRACELET Study)
This work aims to use wearable sensors to record the return towards normal physical activity after breast surgery. It will build on current evidence by using objective measures of activity and arm movements rather than patient…
- Trial name
- BRACELET (NCT03635723)
- Testing
- Activity monitor
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- Imperial College London
Breast Cancer
Preoperative Breast Magnetic Resonance Imaging for Patients Undergoing Mammoplasty
all female with operable breast cancer seeking health care at general surgery department Assiut university hospitals,and decision of therapeutic mammoplasty was taken depending on clinical examination, findings on mammography and…
- Trial name
- NCT03173469
- Testing
- magnetic resonance imaging of breast
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Thyroid Neoplasms
Comparative Study in Oral, Breast Approach and Open Thyroidectomy
Purpose: Total endoscopic thyroidectomy including oral approach and breast approach has excellent cosmetic and several functional results.
- Trial name
- NCT03479801
- Testing
- Thyroid Surgical Methods
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Cancer
Evaluating New Surgical Technique in Management of Female Patients With Operable Multifocal Breast Cancer
Multi-focal Breast Cancers(MFBC) still have undiscoverable Clinical Significance reflecting on a debatable surgical decision for this Category of breast cancer.
- Trial name
- NCT03900299
- Testing
- oncoplastic breast surgery
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Alexandria University
Breast Cancer
Timing of Menstrual Cycle and Surgery in Treating Premenopausal Women With Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: The timing of breast cancer surgery within the menstrual cycle may affect outcome. It is not yet known if treatment is more effective during the initial or final phase of the menstrual cycle.
- Trial name
- NCT00005079
- Testing
- conventional surgery
- Where
- 2 sites in United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer, Breast Neoplasms
Influence of Multidisciplinary Breast Tumor Board on Physician Decision
In our study, the treatment plan for the case prior to the breast tumor counseling will be asked to physician and the treatment protocol observed by the primary physician will be observed after the decision of the tumor council.
- Conditions
- Breast Cancer, Breast Neoplasms, Surgery, Oncology
- Trial name
- NCT03596463
- Testing
- Breast cancer treatment
- Volunteers
- 120 people
- Sponsor
- Okan University
Breast Cancer
Radiotherapy After Primary Chemotherapy for Breastcancer
The primary aim of the study is to evaluate the 5 yr locoregional recurrence rate (LRR) in cT1-2cN0-1(cytology/histology and/or positive SN, excluding patients with > 3 pathologic axillary nodes on imaging) breast cancer…
- Trial name
- RAPCHEM (NCT01279304)
- Testing
- radiation - no radiation see intervention description, radiation: see intervention description
- Where
- 6 sites in Netherlands
- Volunteers
- 851 people
- Sponsor
- Maastricht Radiation Oncology
Breast Cancer
Comparison of MRI and CEDM to Evaluate Treatment Response Before Surgery
The purpose of this study is to compare the diagnostic accuracy of breast magnetic resonance imaging (MRI) and contrast enhanced digital mammography (CEDM) in assessing the residual disease extent in patients who have completed…
- Trial name
- NCT03070340
- Testing
- Breast Magnetic Resonance Imaging (MRI), Contrast Enhanced Mammography (CEDM)
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Analysis of Breast-Conserving Surgery Plus Whole-Breast Irradiation Versus Mastectomy
This is a retrospective propensity score-matched analysis of a large institutional cohort of patients in order to compare long-term outcomes and clinicopathologic characteristics between patients treated with breast conserving…
- Trial name
- NCT05126667
- Testing
- Breast-conserving surgery, Mastectomy
- Volunteers
- 9,710 people
- Sponsor
- European Institute of Oncology
Breast Cancer, Right or Left Breast Mammary Reconstruction
Psycho-esthetic Impact of Tattoo Technology as Part of Mammary Reconstruction After Surgery Against Breast Cancer
Mammary reconstruction replaces total skin transplant, which may causing patient discomfort. It is a simple, painless and reproductible technology that avoids consequences and complications related to transplant.
- Conditions
- Breast Cancer, Right or Left Breast Mammary Reconstruction, Malignant Neoplasm Reconstruction by Tattoo of Areola of Female Breast
- Trial name
- NCT02464982
- Testing
- Tattoo
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer
A Pilot Study to Evaluate Nipple-Areolar Complex (NAC) Sparing Mastectomy
The goal of this study is to study nipple-areolar complex (NAC) sparing mastectomy as an alternative procedure to the standard skin-sparing mastectomy for women who have breast cancer or are at high-risk for developing breast…
- Trial name
- NCT00539227
- Testing
- NAC Sparing Mastectomy, Questionnaire
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Swebcg 91:A RT. Breast Conserving Surgery With or Without Radiotherapy for Breast Cancer Patients
The main goal of the trial was to analyse the value of radiotherapy after breast conserving surgery for patients with breast cancer, and to find groups of patients where the treatment could be omitted.
- Trial name
- NCT06637202
- Testing
- postoperative radiotherapy
- Where
- Sweden
- Volunteers
- 1,187 people
- Sponsor
- Region Skane
Invasive Breast Cancer
Comparison of CNB and Surgical Specimens for ER, PgR, HER2 Status and Ki67 Index in Invasive Breast Cancer.
This is a prospective, single-center, non-randomized, non-controlled study. The estrogen receptor (ER), progesterone receptor (PgR), HER2 status and Ki67 index of CNB specimen are critical biomarkers for making neoadjuvant…
- Trial name
- NCT02773784
- Testing
- immunohistochemistry and/or FISH
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Peking University
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Breast Neoplasms
Application of Intra-operative Prophylactic Antibiotics/Antiseptics in Chinese Breast Reconstruction Patients
The study aims to investigate different approaches of local application of antibiotics/antiseptics intraoperatively in Chinese patients undergoing post-mastectomy implant based breast reconstruction, and aims to single out an…
- Trial name
- NCT03742908
- Testing
- Cefazolin/clindamycin
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital