Clinical trials: Breast Milk Expression
Pain, Preterm
The Nonpharmacological Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants
According to the World Health Organization, preterm birth (from 20 to 37 gestation week) is a significant global health problem, as preterm infants represent an estimated 15 million infants per year worldwide.
- Conditions
- Pain, Preterm, Premature
- Trial name
- NCT04006743
- Testing
- The swaddling group, The expressed breast milk group, The facilitated tucking group
- Where
- Turkey (Türkiye)
- Volunteers
- 187 people
- Sponsor
- Akdeniz University
Breastfeeding, Breastmilk Expression
Pumping to Up Maternal Milk Production for Preterms
The goal of this clinical trial is to learn about the effect of breast-pumping frequency on breast milk supply/ volume in mothers of preterm infants.
- Trial name
- PUMMPP (NCT06673160)
- Testing
- Pumping every 2 hours, breast pumping every 3 hours
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Alabama at Birmingham
Breastfeeding, Preterm Birth
Sodium Awareness in Lactation Trial
SALT is a multi-centre, non-blinded, non-randomized prospective interventional pilot study teaching lactating parents of hospitalized preterm infants how to test their breastmilk sodium (Na) using point-of-care (POC) meters.
- Conditions
- Breastfeeding, Preterm Birth, Breast Pumping, Lactation; Insufficient, Partial
- Trial name
- SALT (NCT06563726)
- Testing
- point-of-care milk sodium testing
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Breastfeeding, Prematurity
Maximising Maternal Milk for Preterm Infant
Maternal milk is the gold standard in infant nutrition, providing significant advantages, in preterm and term infants. Maternal milk plays a major role in reducing the risk of inflammatory bowel disease(NEC) in premature and low…
- Trial name
- MILQ prem (NCT07908238)
- Testing
- Hospital grade double electrical breast milk pump
- Where
- 3 sites in Ireland
- Volunteers
- 160 people
- Sponsor
- National Maternity Hospital, Ireland
Breast Milk Collection
Factors Influencing the Composition of Human Milk
This study aims for characterization of different maternal, infant and environmental factors (e.g. maternal age, pregnancy duration, lactation period, baby gender, circadian rhythm, Holder pasteurisation, etc.) that influence…
- Trial name
- NCT04382989
- Testing
- Analysis of human milk composition by mid-infrared spectrophotometry
- Where
- Lithuania
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Vitamin D Deficiency, Breast Milk Collection
Vitamin D Sulfates in Breastmilk
Infants The purpose of this study is to measure breastmilk's vitamin D sulfate nutritional value in infant's saliva and digesta (gut).
- Trial name
- NCT06203041
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breastfeeding Mothers of Infants Hospitalized
The "Pooling" Expressed Breast Milk: A Method for Improving the Nutritional Intake of Premature Infants
The investigators compared a pooled mother's expressed breastmilk for 24 hours with individual pump session collection of milk to provide a more consistent caloric product without increasing bacterial contamination.
- Trial name
- POOL-BM (NCT02994823)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Breastfeeding, Breastfeeding, Exclusive
The Effect of Prenatal Hand Expression on the Rate of Exclusive Breastfeeding to Two Months
Despite recommendations by several health authorities, the rate of sustained exclusive breastfeeding for two months is less than fifty-five percent in Canada.
- Conditions
- Breastfeeding, Breastfeeding, Exclusive, Breast Milk Collection
- Trial name
- NCT05066438
- Testing
- Antenatal hand expression
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Breast Milk Collection, Nutrition Disorder, Infant
Analysis of Donor Milk
The purpose of this prospective, cross-sectional, observational study is to measure the nutrient composition of donated human breastmilk purchased from commercial human milk banks in North America
- Trial name
- DOME (NCT05742815)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Augusta University
Postpartum, Lactation
Drug Excretion in Breast Milk
This is a prospective, non-randomized, phase I study design evaluating the in vivo activities and expression of OCT1 and BCRP in mammary gland of lactating women at three time points postpartum.
- Conditions
- Postpartum, Lactation, Drugs in Breast Milk, Mammary Drug Transporters
- Trial name
- NCT06056583
- Testing
- Cimetidine 200 MG
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Washington
Breastfeeding
FamilyLink and Breastfeeding
The central hypothesis guiding this project is that having mothers view live video of their babies while they are pumping increases milk volume, caloric density, and maternal pumping experience.
- Trial name
- NCT03957941
- Testing
- FamilyLink Pumping, Standard Pumping
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, Davis
Pain, Premature Infant
Efficacy of Breast Milk Expressed and Sucrose in Procedural Pain in Preterm
The aim of this study is to assess the non-inferiority of non- pharmacological breast milk expressed versus oral sucrose in relief procedural pain of venipuncture in preterm neonates.
- Conditions
- Pain, Premature Infant, Human Milk, Breastfeeding
- Trial name
- LACTEET (NCT02133716)
- Testing
- expressed breast milk, sucrose 24% oral
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Formula Milk, Breast Milk Collection
Metabolomic Profile in Breastfed Late Preterm Infants
Exclusive breast milk is recommended from birth to 6 months of life to promote the development of a balanced intestinal microbiota.
- Conditions
- Formula Milk, Breast Milk Collection, Postbiotic Supplemented Formula Milk
- Trial name
- NCT06052592
- Testing
- Milk
- Where
- 2 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Breast Feeding, Exclusive Breastfeeding
At-the-Breast vs. Expressed Human Milk: Genesis of Infant Nutrition (BEGIN)
The purpose of this study is to define human milk (HM) as an ecosystem which investigators will then combine into temporal models of milk dynamics to accurately describe HM chronobiology.
- Trial name
- BEGIN (NCT06691932)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Rochester
Breast Milk Expression, Breast Milk Collection
The Effect of Showing Photographs, Videos and Live Images of Their Babies to Mothers During Milking
The study was planned to determine the effect of showing photographs, videos and live images of premature babies who could not be breastfed in the neonatal intensive care unit to their mothers on the amount of breast milk…
- Conditions
- Breast Milk Expression, Breast Milk Collection, Mother-Infant Interaction
- Trial name
- NCT05700162
- Testing
- Photograph, Video, Live Broadcast
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Breast Feeding, Milk Expression, Breast
Reproductive Health Outcomes by Method of Breast Milk Feeding
The purpose of this research is to determine whether there are differences in ovarian suppression between women who are feeding at the breast compared with women who are pumping.
- Conditions
- Breast Feeding, Milk Expression, Breast, Amenorrhea, Postpartum
- Trial name
- NCT03568851
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- University of California, Davis
Breast Milk Collection
the Study of Persistent Organic Pollutants in Human Milk
The study aims to recruit eligible participants and conduct interviews, collect human milk samples, and conduct laboratory analysis of persistent organic pollutants' levels in human milk samples.
- Trial name
- NCT04102085
- Testing
- no intervention
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Breast Feeding, Breast Milk Expression
Stress and Breast Milk Study In the Neonatal Intensive Care Unit
The overall goal of this research is to clarify the relationship between reported maternal stress, biological measures of maternal stress, breast milk biomarkers and milk quantity.
- Conditions
- Breast Feeding, Breast Milk Expression, Stress
- Trial name
- NCT03617549
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Rochester
Breast Milk Collection
Analysis of Lipids in Human Milk At Different Gestational Ages
Various studies have shown that the milk of a preterm infant differs from that of a term infant in the composition of micronutrients, vitamins, macronutrients, carbohydrates and proteins.
- Trial name
- NCT05989009
- Testing
- Breastfeeding
- Where
- 2 sites in Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Breast Milk Collection, Infant Development
Assessing Changes in Breastmilk Composition Over Time Among Pakistani Infants
In Pakistan, breastfeeding is widely practiced. National data suggests that 94% of infants <2 years of age receive breastmilk at some point. However, the introduction of complementary foods often occurs early.
- Trial name
- NCT04450056
- Testing
- No intervention
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Aga Khan University