Clinical trials: Breath Tests
Childhood Asthma
More Relaxation by Deep Breath on Methacholine
Deep inhalation (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation.
- Trial name
- SouProvocBro (NCT03696602)
- Testing
- bronchial provocation test
- Volunteers
- 78 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Mesenteric Ischemia
Chronic Mesenteric Ischemia Breath Testing
Background and aims: A gold standard diagnostic test to diagnose chronic mesenteric ischemia is currently lacking. Isotope labelled-butyrate and glucose breath testing could theoretically quantify mucosal oxygen consumption and…
- Trial name
- NCT06022588
- Testing
- Sodium butyrate, 1-13C, 99%, Cambridge Isotope Laboratories, Inc.USA, U-13C6, 99%; Cambridge Isotope Laboratories, Inc.USA, Breath test
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
H. Pylori Infection
Establish Epidemiologic Data of H. Pylori Infection in Children and Adolescents-Using C13-UBT
The aims of this prospective study are: (1) to prospectively investigate the "true" prevalence rate, the acquisition and spontaneous clearance of H.
- Trial name
- NCT00155623
- Where
- Taiwan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Phenylketonuria (PKU)
Simple Breath Test to Examine Phenylalanine Metabolism
Phenylketonuria(PKU)is a rare condition caused by the body's inability to properly breakdown an amino acid called phenylalanine(PHE), due to a missing enzyme, phenylalanine hydroxylase(PAH).
- Trial name
- NCT02009904
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Small Intestinal Bacterial Overgrowth
Hydrogen and Methane Breath Test Questionnaire
Lactulose HMBT and Glucose HMBT are simple non-invasive tests to assess whether imbalances in gut bacteria may be contributing to troublesome tummy symptoms.
- Trial name
- HMBTQ (NCT05122520)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 1,040 people
- Sponsor
- The Functional Gut Clinic
Weightlifting, Breathing
The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes
The effects of manipulation therapy on the autonomic nervous system have been examined in the literature and while no sympathetic or parasympathetic changes were found after upper thoracic manipulation, a decrease in sympathetic…
- Conditions
- Weightlifting, Breathing, Breath Tests, Athlete
- Trial name
- NCT06606795
- Testing
- Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cystic Fibrosis, Lung Inflammation
TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era
Progressive destruction of the lungs is the main cause of shortened life expectancy in people with cystic fibrosis (pwCF). Inflammation and respiratory infections play a key role in CF lung disease.
- Conditions
- Cystic Fibrosis, Lung Inflammation, Lung Infection, Lung Disease; Cystic
- Trial name
- TERRIFIC-MILE (NCT05752019)
- Where
- Netherlands
- Volunteers
- 103 people
- Sponsor
- Erasmus Medical Center
Breath Exercise, Test Anxiety
The Effects of Breathing Exercises Administered to Associate Degree Students on Test Anxiety and Academic Achievement
This study aims to examine the effects of breathing exercises administered to associate degree students on test anxiety and academic achievement.
- Conditions
- Breath Exercise, Test Anxiety, Higher Education Students, Academic Achievement
- Trial name
- NCT07145021
- Testing
- Breathing Exercise Intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Larynx Cancer
Breath Testing in Early and Late Larynx Cancer
It is possible to test a sample of breath from a patient, run it through a machine, and find out certain diseases in the patient without needing to do Xrays.
- Trial name
- NCT01700647
- Testing
- Breath test- sampling using ENose, Laryngoscopy and bronchoscopy
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Royal Brisbane and Women's Hospital
Asthma, Cystic Fibrosis
Breath Analysis in Children by New Point-of-care Instruments
In this study new hand-held devices for measuring exhaled breath will be tested in children with asthma, CF, and healthy controls. Main objectives will be feasibility and discriminative value of these techniques.
- Trial name
- NCT03377686
- Testing
- inflammation markers in exhaled breath
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Helicobacter Pylori, Safety
PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study
This is a multi-center, non-randomized, open label study. Subjects will be enrolled on a walk-in basis. Screening data will be reviewed to determine subject eligibility.
- Conditions
- Helicobacter Pylori, Safety, Efficacy
- Trial name
- NCT05276557
- Testing
- PyloPlus Urea Breath Test System, Stool Antigen Test
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARJ Medical, Inc.
Tuberculosis
eNose-TB: Electronic Nose for Tuberculosis Screening
An electronic-nose (e-nose) is being investigated as a diagnostic tool for tuberculosis by examining exhaled breath of the patients. Universitas Gadjah Mada has developed an e-nose device for TB diagnostic tool.
- Trial name
- NCT04567498
- Testing
- exhaled breath sampling
- Where
- 3 sites in Indonesia
- Volunteers
- 1,778 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Cystic Fibrosis in Children
Determinants of Early Cystic Fibrosis Lung Disease
The overall objective of this study is to determine the impact early nutritional and respiratory indices have on early CF lung disease.
- Trial name
- NCT03579173
- Testing
- Infant PFT, Lung Clearance Index, Passive tidal breathing
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Indiana University
Gastrointestinal Disease, Esophageal Cancer
PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide
The goal of this clinical research study is to use a new breathing test that measures the amount of nitric oxide (NO) you exhale.
- Conditions
- Gastrointestinal Disease, Esophageal Cancer, Lung Cancer
- Trial name
- NCT00867477
- Testing
- Breathing Test, Respiratory Symptoms Questionnaire, Pet Scan
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- M.D. Anderson Cancer Center
Asthma
Development of a Breath Analyzer for Asthma Screening
Annually, asthma is responsible for 1 million emergency room visits, 400,000 hospitalizations, and 5000 deaths according to the NHLBI.
- Trial name
- NCT00386737
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ekips Technologies
Dyspnea, Unexplained Chronic Dyspnea
Establishing Clinical Utility for a New Diagnostic Test for Patients With Shortness of Breath
This study will collect high-quality data on how practicing specialist physicians, specifically cardiologists and pulmonologists, across the U.S.
- Trial name
- NCT04693793
- Testing
- Education Materials and Janssen Test
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Infection, Community-Acquired, Communicable Disease
Infection Detection by Breath Analysis
The purpose of this feasibility study is to test a device which analyzes breath and may allow doctors and health professionals to immediately determine if an ill patient has a specific type of bacterial infection.
- Conditions
- Infection, Community-Acquired, Communicable Disease, Respiratory Infection
- Trial name
- NCT02981550
- Sponsor
- BreathTec Biomedical Inc.
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Primary Ciliary Dyskinesia
Respiratory Physiotherapy Performed by Simeox In Patients With Primary Ciliary Dyskinesia
Primary ciliary dyskinesia (PCD) is characterized by impaired airway clearance and mucus stagnation. This results in recurrent upper and lower respiratory tract infections often leading to chronic inflammation and, if not treated…
- Trial name
- NCT04793724
- Testing
- Simeox, PARI O PEP
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol