Clinical trials: Breathlessness
Pneumonia, Fever
VRI in Children With Acute Respiratory Symptoms.
The VRI technology provides a radiation free dynamic image of the lung, by using a combination of well-known technologies, i.e. acoustic sensors, and a proprietary algorithm.
- Trial name
- VRI (NCT01279863)
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Respiratory Disease, Respiratory Insufficiency
Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room
Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room In Late Preterm And Term Infants Wıth Respiratory Distress
- Trial name
- NCT04282369
- Testing
- HHHFNC, NCPAP, NIPPV
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Respiratory Decompensation, Multiple Disabilities
Long-term Use of Intrapulmonary Percussive Ventilation for Preventing Hospitalizations Due to Respiratory Decompensation in Children With Multiple Disabilities
Chronic respiratory failure is the leading cause of morbidity and mortality in children with multiple disabilities. Musculoskeletal disorders, swallowing disorders and ventilatory control abnormalities lead to progressive…
- Trial name
- PERKINE (NCT07473856)
- Testing
- Intrapulmonary Percussive Ventilation IPV
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Diseases
Auto-evaluation of Dyspnea
The primary aim of this study was to compare patients-rated evaluation and caregiver's assessment of dyspnea with the standard tools in pulmonology unit (Borg scale and visual analog scale) and the secondary aim was to performed…
- Trial name
- NCT03598569
- Testing
- dyspnea
- Where
- Belgium
- Volunteers
- 271 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Transient Hypothyroxinemia, Infant, Newborn
Thyroid Function in Term Infants With Respiratory Distress
This study was designed to evaluate the level of certain hormones (thyroid hormones and cortisol) in full term or close to full term infants who have respiratory distress severe enough to require respiratory support.
- Trial name
- NCT00293956
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Christiana Care Health Services
Neuromuscular Diseases
Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease
The main objective of this study is to determine whether the Respiratory Physiotherapy allows improvement or maintenance of respiratory function in children with Neuromuscular Diseases, against respiratory deterioration that…
- Trial name
- NCT02743702
- Testing
- RESPIRATORY PHYSIOTHERAPY, USUAL THERAPIES
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- University of Seville
Eclampsia, Severe Pre-eclampsia
Pulmonary Edema Resolution in Severe Preeclampsia and Eclampsia
Patients with severe preeclampsia or eclampsia suffer from pulmonary complications. Accurate assessment of patients with pulmonary involvement using lung ultrasound (LUS) and echocardiography could lead to earlier detection of…
- Trial name
- TiPER (NCT06219109)
- Where
- Sierra Leone
- Volunteers
- 55 people
- Sponsor
- Doctors with Africa - CUAMM
Asthma
Study of Safety of QAW039 in Patients With Asthma Inadequately Controlled on Standard-of-care Asthma Treatment
This study was a 2-treatment period, randomized, multicenter parallel-group study. The overall purpose of this study was to provide long- term safety data for fevipiprant (QAW039) (Dose 1 and Dose 2), compared with placebo, when…
- Trial name
- NCT03052517
- Testing
- QAW039 150 mg, QAW039 450 mg
- Where
- 347 sites in United States, Argentina and 40 more
- Volunteers
- 2,538 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA)
This is a multicenter, randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of subcutaneously administered Xolair as add-on therapy for the treatment of subjects aged 12-75 years old…
- Trial name
- NCT00314574
- Testing
- omalizumab (Xolair), corticosteroids, long-acting beta-agonists
- Volunteers
- 850 people
- Sponsor
- Genentech, Inc.
Chronic Obstructive Pulmonary Disease (COPD)
Management of Patients With Respiratory Symptoms in Sweden
This is a web-based randomized survey to evaluate management of respiratory symptoms among physicians in Sweden. The aim of this study is to determine if there is a gender bias in the diagnosis of COPD and how often physicians…
- Trial name
- NCT02728674
- Testing
- Person in the case is a male., Person in the case is a female., Symptom in the case is breathlessness.
- Where
- Sweden
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Hypoxia, Respiratory Distress
Advancement of Modified Bubble CPAP
This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality…
- Trial name
- NCT02208323
- Testing
- Bubble CPAP
- Where
- Uganda
- Volunteers
- 87 people
- Sponsor
- University of Minnesota
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Death, Pain
Intervention to Improve Care at Life's End
The BEACON trial (Best Practices for End-of-Life Care for Our Nations' Veterans) was a six-site implementation study to evaluate a multi-component, education-based intervention to improve the quality of end-of-life care provided…
- Conditions
- Death, Pain, Dyspnea
- Trial name
- BEACON (NCT00234286)
- Testing
- Comfort care education intervention
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- US Department of Veterans Affairs
Dyspnea, Heart Failure
Dyspnea and Biomarkers in a Prehospital Setting
In patients presenting with acute dyspnea in a pre-hospital setting, the early and correct diagnosis may present a significant clinical challenge.
- Conditions
- Dyspnea, Heart Failure, Asthma, COPD
- Trial name
- NCT00878475
- Where
- Slovenia
- Volunteers
- 546 people
- Sponsor
- Community Healthcare Center dr. Adolf Drolc Maribor (HCM)
Copd, Dyspnea
Effects of Menthol on Dyspnoea in COPD Patients
Chronic obstructive pulmonary disease (COPD) is characterised by non-reversible bronchial obstruction associated with systemic disorders and comorbid factors.
- Conditions
- Copd, Dyspnea, Lung Diseases
- Trial name
- MEDiC (NCT03626519)
- Testing
- Test with Menthol
- Where
- 3 sites in France
- Volunteers
- 63 people
- Sponsor
- Groupe Hospitalier du Havre
Acute Viral Bronchiolitis
High Flow Therapy vs Hypertonic Saline in Bronchiolitis
The purpose of this study is to demonstrate that heated, humidified, high-flow nasal cannula (HHHFNC) is superior to hypertonic saline solution (HSS) in the treatment of moderate acute viral bronchiolitis in infants in improving…
- Trial name
- NCT01873144
- Testing
- Epinephrine 1/1000, HSS 3%, HHHFNC
- Where
- 2 sites in Spain
- Volunteers
- 75 people
- Sponsor
- Ministry of Health, Spain
Pulmonary Disease, Chronic Obstructive
Randomized Controlled Trial of Mind-Body Breathing Therapy (in Chronic Obstructive Pulmonary Disease) To Improve Palliation of Dyspnea and Health-Related Quality of Life
Dyspnea (shortness of breath) is a complex experience that includes interpretation of physical impairments and associated distress to the person.
- Trial name
- NCT00243282
- Testing
- Relaxation Response (instruction, pocket practice card prov), Mindfulness training using model developed from UMass
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- US Department of Veterans Affairs
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Hypoxemic Acute Respiratory Distress, Infant Between 1 Month and 24 Months Old
Automatic Oxygen Administration During the Respiratory Distress in Infants and Children (Infant-FreeO2)
The aim of the study is to assess the use feasibility of the FreeO2 system so as to deliver automatically oxygen in infants and children admitted at hospital for hypoxemic acute respiratory distress.
- Conditions
- Hypoxemic Acute Respiratory Distress, Infant Between 1 Month and 24 Months Old, Child Between 2 and 15 Years Old
- Trial name
- Infant-Free02 (NCT02302183)
- Testing
- FreeO2 v2.0 automatic adjustment, FreeO2 v2.0 data collecting
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Dyspnea and Respiratory Insufficiency in Children
Multidimensional Characterization of Dyspnea in Children
There is no specific tool existing to describe dyspnea in children in a multidimensional way. It has been shown in adult studies that multidimensional dyspnea evaluation scales are well correlated to quality of life and…
- Trial name
- DYSPED (NCT05500833)
- Testing
- Multidimentional observation scale (MDP)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris