Clinical trials: Bronchiolitis Acute
Acute Disease Respiratory
Use Of The ABSS In Infants With ARIS Treated With Outpatient Respiratory Physiotherapy
Background. Acute respiratory infections in childhood have high incidence and morbimortality rates, generating significant sanitary and social costs.
- Trial name
- NCT04036591
- Testing
- Acute Bronchiolitis Severity Scale (ABSS)
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- FisioRespiración
Bronchiolitis, Viral
Single Injection of Dexamethasone for Acute Bronchiolitis in Young Children
The purpose of this study was to determine whether a single intramuscular injection of dexamethasone decreased the duration of symptoms of acute bronchiolitis in young children.
- Trial name
- NCT00122785
- Testing
- dexamethasone
- Where
- Thailand
- Volunteers
- 170 people
- Sponsor
- Khon Kaen University
Respiratory Diseases, Chronic and Acute Respiratory Failure
Validation of a Simulated Clinical Evaluation of Ventilators
The purpose of this study is to evaluate the ability of a device reproducing patients' respiratory characteristics to select in-VITRO the most appropriate ventilator for a given pathology.
- Trial name
- SIMULVENTI (NCT01113255)
- Testing
- bench-evaluation, of three ventilators
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Injury, Acute, Respiratory Distress Syndrome, Adult
Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant
The purpose of this study is to determine the effectiveness of etanercept in the treatment of patients with sub-acute lung injury following a bone marrow transplant.
- Conditions
- Lung Injury, Acute, Respiratory Distress Syndrome, Adult, Bronchiolitis Obliterans
- Trial name
- NCT00141726
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Michigan Rogel Cancer Center
Acute Bronchiolitis
Evaluation of the Effects of Respiratory Physiotherapy in Infants With Moderate Acute Bronchiolitis
Bronchiolitis affects 460,000 children in France per year. The French study called "Bronkilib 2" found a positive effect of chest physiotherapy treatment.
- Trial name
- Bronkiville (NCT03753802)
- Testing
- Chest Physiotherapy, Surveillance
- Where
- 3 sites in France
- Volunteers
- 168 people
- Sponsor
- Réseau Kinésithérapie Bronchiolite Essonne
Stem Cell Transplant Complications
KIR Sequencing and Typing for Allograft in Nancy
The use of haploidentical donors for aHSCT has greatly increased this past decade leading to a major paradigm shift: while finding 10/10 HLA-matched donors represented the prior difficulty for decades, the current problem is…
- Trial name
- KIR-STAN (NCT04882605)
- Testing
- MHC typing, KIR typing, Assessment of KIR-based prediction scores
- Volunteers
- 156 people
- Sponsor
- Central Hospital, Nancy, France
Bronchiolitis Acute
Use of Lung Ultrasound in Children With Acute Bronchiolitis
Bronchiolitis is the leading cause of hospitalization in infants. The diagnosis is clinical and chest x-ray (CXR) should be reserved for severe cases in which signs of pulmonary complications are present.
- Trial name
- NCT03280732
- Testing
- Lung Ultrasound
- Where
- Italy
- Volunteers
- 87 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chronic Graft-versus-Host-Disease, Leukemia
Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study
This study will validate a previously developed pediatric prognostic biomarker algorithm aimed at improving prediction of risk for the later development of chronic graft-versus-host disease (cGvHD) in children and young adults…
- Conditions
- Chronic Graft-versus-Host-Disease, Leukemia, Allogeneic Hematopoietic Stem Cell Transplantation, Blood Cancer
- Trial name
- NCT04372524
- Where
- 16 sites in United States, Canada
- Volunteers
- 350 people
- Sponsor
- University of British Columbia
Viral Bronchiolitis
Evaluation of Chest Physiotherapy for Acute Bronchiolitis in Toddlers (BRONKINOU)
The purpose of this study is to determine whether chest physiotherapy with forced expiratory technique reduces delay of healing in acute bronchiolitis of children between 15 days and 24 months of age.
- Trial name
- BRONKINOU (NCT00125450)
- Testing
- Chest Physiotherapy with Forced Expiratory Technique, Nasopharyngeal Aspiration
- Where
- 7 sites in France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Bronchiolitis
Acute Bronchiolitis and Severity Markers: Interest in Protein CC16
Acute bronchiolitis is a common viral infection in infants mainly due to RSV and rhinovirus. Biomarkers can be useful for predicting its severity. The serum CC16 is a marker of epithelial aggression.
- Trial name
- CC16 (NCT02984046)
- Testing
- Protein CC16
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Bronchiolitis
FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma
The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.
- Trial name
- NCT02093715
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute Viral Bronchiolitis
High Flow Therapy vs Hypertonic Saline in Bronchiolitis
The purpose of this study is to demonstrate that heated, humidified, high-flow nasal cannula (HHHFNC) is superior to hypertonic saline solution (HSS) in the treatment of moderate acute viral bronchiolitis in infants in improving…
- Trial name
- NCT01873144
- Testing
- Epinephrine 1/1000, HSS 3%, HHHFNC
- Where
- 2 sites in Spain
- Volunteers
- 75 people
- Sponsor
- Ministry of Health, Spain
Acute Bronchiolitis
The SABRE Trial of Hypertonic Saline in Acute Bronchiolitis
Acute bronchiolitis is a common, distressing illness affecting children. A virus infects the lungs, and then the airways become blocked, leading to difficulties with breathing.
- Trial name
- SABRE (NCT01469845)
- Testing
- 3% hypertonic saline
- Where
- 9 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheffield Children's NHS Foundation Trust
Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute
Mucociliary Clearance Techniques for Acute Bronchiolitis
To assess the efficacy of mucociliary clearance techniques in non-hospitalised infants with a first episode of mild to moderate acute bronchiolitis.
- Conditions
- Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute, Bronchiolitis Acute Viral
- Trial name
- CLEARBRONCH (NCT06689631)
- Testing
- Respiratory Physiotherapy
- Volunteers
- 70 people
- Sponsor
- Universidad de León
Acute Lower Respiratory Tract Infection, Pneumonia
Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection
The purpose of this study is to determine whether vitamin D supplements given to children aged 1 month to 5 years, hospitalized with acute lower respiratory tract infection will improve symptoms and reduce the duration of…
- Conditions
- Acute Lower Respiratory Tract Infection, Pneumonia, Bronchiolitis
- Trial name
- NCT02054182
- Testing
- Vitamin D
- Where
- South Africa
- Volunteers
- 320 people
- Sponsor
- University of Limpopo
Acute Viral Bronchiolitis
Effects of Rhinopharyngeal Retrograde Clearance in Children With Acute Viral Bronchiolitis
The purpose of this study is to compare the immediate effects of retrograde rhinopharyngeal clearance with nasopharyngeal aspiration in children admitted with acute viral bronchiolitis.
- Trial name
- NCT02460614
- Testing
- Rhinopharyngeal clearance, Aspiration, 0.9% saline
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Wounds and Injuries, Burns
Treatment of Wounds With a New Adhesive Foam Dressing
This study will look at whether ELECT, a new adhesive foam dressing, can offer an alternative to traditional wound care methods. Patients will be treated with ELECT for 14 days.
- Trial name
- NCT02807584
- Testing
- ELECT
- Where
- South Africa
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Graft Versus Host Disease
Allogenic Bone Marrow Mesenchymal Stem Cells Infusion in Patients With Steroid-refractory GVHD
Graft versus host disease is a serious and often life-threatening complication in allogeneic haematopoietic stem cell transplantation.
- Trial name
- NCT02824653
- Testing
- Mesenchymal Stem Cells
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
Graft Versus Host Disease, Acute Graft Versus Host Disease
BMT Autologous MSCs for GvHD
Subjects in this study have had an allogeneic (blood or marrow cells from another person) blood or marrow transplant to treat leukemia, lymphoma or other cancer of the blood, and have now developed Graft Versus Host Disease…
- Conditions
- Graft Versus Host Disease, Acute Graft Versus Host Disease, Chronic Graft Versus Host Disease
- Trial name
- NCT02359929
- Testing
- Autologous mesenchymal stromal cells (MSCs)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Emory University
Acute Bronchiolitis Due to Respiratory Syncytial Virus
Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis
The goal of this clinical trial is to compare the efficacy of hypertonic saline nebulization with adrenaline nebulization in the treatment of acute bronchiolitis in children.
- Trial name
- children (NCT06267118)
- Testing
- Hypertonic Saline Solution, 1 Ml, Adrenaline
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital, Pakistan