Clinical trials: Bronchitis
Wheezing, Bronchiolitis
Bedside Lung Ultrasound in Young Children Presenting to the Emergency Department (ED) With Wheezing
Young children presenting to the Emergency Department (ED) with wheezing often have prolonged stays in the ED or even get admitted to the hospital.
- Trial name
- NCT01452945
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's National Research Institute
Acute Asthma, Acute Wheezy Bronchitis
Effect of Addition Oral Montelukast to Standard Treatment in Acute Asthma in Hospitalized Preschool Children
Leukotriene receptor antagonists (LTRAs) are well established in the management of outpatient asthma. Montelukast is a potent, specific, orally active, cysteinyl leukotriene receptor antagonist with a rapid onset of…
- Trial name
- NCT03369119
- Testing
- Montelukast 4 Mg Oral Granule
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kecioren Education and Training Hospital
Wheezy Bronchitis, Asthmatic Bronchitis
Efficacy of Intermittent Tiotropium in Early Childhood Wheezing
This study evaluates the effect of intermittent tiotropium bromide and salbutamol as needed versus intermittent fluticasone propionate and salbutamol as needed, or solely, salbutamol as needed on episode-free days in infants and…
- Conditions
- Wheezy Bronchitis, Asthmatic Bronchitis, Wheezing, Obstruction Airway
- Trial name
- NCT03199976
- Testing
- Tiotropium Bromide, Fluticasone Propionate, Salbutamol
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Bronchiolitis
Study of High-flow Oxygen Therapy Against Standard Therapy in Bronchiolitis
Bronchiolitis is a common illness of the respiratory tract caused by infection of the tiny airways within the lungs called bronchioles.
- Trial name
- Hi-Flo (NCT01498094)
- Testing
- High Flow Nasal Cannula Oxygen Therapy, Standard low flow oxygen
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- University of British Columbia
Acute Bronchiolitis
Evaluation of the Effects of Respiratory Physiotherapy in Infants With Moderate Acute Bronchiolitis
Bronchiolitis affects 460,000 children in France per year. The French study called "Bronkilib 2" found a positive effect of chest physiotherapy treatment.
- Trial name
- Bronkiville (NCT03753802)
- Testing
- Chest Physiotherapy, Surveillance
- Where
- 3 sites in France
- Volunteers
- 168 people
- Sponsor
- Réseau Kinésithérapie Bronchiolite Essonne
Bronchiolitis Obliterans
A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHD
Approximately 10,000 allogeneic hematopoietic stem cell transplants (HSCT) are performed annually in the US for various indications.
- Trial name
- NCT01163786
- Testing
- Bortezomib
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Northwestern University
Chronic Myeloid Leukemia (CML)
Chronic Myeloid Leukemia (CML) Real-Life Database
Establish the largest possible real-life cohort collecting long-term follow-up of a maximum number of CML patients in order to carry out observational studies: epidemiological, identification of subgroups according to their…
- Trial name
- NCT05963061
- Where
- 14 sites in France
- Volunteers
- 3,500 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bronchiolitis, Anxiety
Evaluation of Virtual Reality Glasses Use During Inhaler Treatment in Children
Virtual reality (VR) glasses are technological devices that are often used in medical fields recently and are seen as suitable for distracting children.
- Trial name
- NCT05839054
- Testing
- Virtual Reality audio and visual glass (Roller Coasters, group 1), Virtual Reality audio and visual glass (Wild Dolphins, group 2)
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Haseki Training and Research Hospital
Obliterative Bronchiolitis
Bronchodilator Responsiveness in Obliterative Bronchiolitis
This study has been designed to provide a substantial evidence of acute bronchodilator responsiveness to two sequentially inhaled drugs, a beta2-agonist (i.e., albuterol) and an anticholinergic (i.e., tiotropium bromide), in a…
- Trial name
- BD-OB (NCT01112241)
- Testing
- albuterol plus tiotropium
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Acute Upper Respiratory Tract Infections, Nasal Obstruction
Influence of Patient Positioning During Nasal Lavage
Acute upper respiratory tract infections are the primary cause of pediatric visits and hospitalizations in young children. Nasal congestion and mucus accumulation often cause discomfort, feeding difficulties, and respiratory…
- Conditions
- Acute Upper Respiratory Tract Infections, Nasal Obstruction, Bronchiolitis
- Trial name
- nasal lavage (NCT07921680)
- Testing
- Supine position nasal lavage, Semi-sitting position nasal lavage
- Where
- Spain
- Volunteers
- 145 people
- Sponsor
- Hospital Universitario La Paz
Respiratory Tract Infections, Pediatric Respiratory Diseases
Bacterial Lysate In Preventing Asthma
Bronchiolitis is a common viral infection of the small airways of infants and some affected infants will require hospital admission.
- Conditions
- Respiratory Tract Infections, Pediatric Respiratory Diseases, Wheezing
- Trial name
- BLIPA (NCT05064631)
- Testing
- Bacterial Lysate
- Where
- 3 sites in United Kingdom
- Volunteers
- 173 people
- Sponsor
- Queen Mary University of London
Chronic Postoperative Pain
Data Collection for Prediction of Postoperative Chronic Pain for a Software
Postoperative Persistent Pain (PPP) is reported with a high incidence in adults 11.5-47%. This high incidence effects quality of life of patients causes social-economical problems and arises medico-legal issues.
- Trial name
- NCT02190682
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 733 people
- Sponsor
- Istanbul University
Bronchiolitis, Bronchitis
Effect of AI-Assisted Discharge Education on Parents of Children With Bronchitis/Bronchiolitis
This randomized controlled trial aims to evaluate the effects of artificial intelligence-assisted discharge education on mothers of children hospitalized with bronchitis/bronchiolitis.
- Trial name
- NCT07774494
- Testing
- AI-Assisted Written Discharge Education, AI-Assisted Video Discharge Education, Routine Discharge Education
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Bronchiolitis, Lower Respiratory Tract Infection
Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial
The goal of this clinical trial is to find out at which lower limit for saturation (amount of oxygen in the blood) we can best give extra oxygen to children that have been admitted for shortness of breath.
- Conditions
- Bronchiolitis, Lower Respiratory Tract Infection, Bronchial Hyperreactivity
- Trial name
- OxyKids (NCT06016244)
- Testing
- Oxygen saturation threshold
- Where
- 9 sites in Netherlands
- Volunteers
- 566 people
- Sponsor
- Spaarne Gasthuis
Bronchiectasis, Cystic Fibrosis
Evaluating Bronchodilator Response in Patients With Bronchiectasis
Although patients with bronchiectasis tend to have non reversible obstructive patterns on pulmonary function tests (PFTs), reversible obstruction is not uncommon.
- Conditions
- Bronchiectasis, Cystic Fibrosis, Primary Ciliary Dyskinesia, Primary Immune Deficiency
- Trial name
- NCT05932316
- Testing
- spirometry, Salbutamol
- Where
- Israel
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Hematopoietic Stem Cell Transplant (HSCT), Bronchiolitis Obliterans (BO)
Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant
Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy, and lung injury affects as many as 25% of children receiving HSCT.
- Trial name
- HSCT (NCT04908735)
- Testing
- Ruxolitinib
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Bronchiolitis
Inhaled Hypertonic Saline Use in the Emergency Department to Treat Acute Viral Bronchiolitis
Acute viral bronchiolitis is an extremely common childhood disease, responsible for approximately 17% of childhood admissions to hospital per year, with an annually cost that reaches U$ 500 million.
- Trial name
- NCT02045238
- Testing
- Hypertonic Saline, Chest X-Ray, Respiratory virus screening test
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo
Bronchiolitis, Bronchiolitis Acute Viral
Analysis of Variability in the Management of Respiratory Infections in Hospitalized Patients Under 2 Years of Age
Medical practice variability refers to differences in treatment and clinical outcomes that cannot be solely explained by patient characteristics or medical conditions.
- Trial name
- NCT07202585
- Where
- Argentina
- Volunteers
- 127 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Bronchiolitis
High Flow Nasal Cannula (HFNC) Initiation Flow Rate Study
The investigators propose an open label, non-blinded, single center randomized controlled feasibility study to find the optimal initial HFNC flow rate in children less than 12 months old with clinically diagnosed moderate to…
- Trial name
- NCT04517344
- Testing
- Initial Flow Rate
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas Southwestern Medical Center
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
Internet-based Behaviour Therapy for Tourette's Disorder and Chronic Tic Disorder
The purpose of this study is to evaluate the feasibility and acceptability of two different modalities of therapist-guided Internet-delivered behaviour therapy (IBT) for children and adolescents (7-17 years) with Tourette's…
- Trial name
- NCT02864589
- Testing
- Internet-delivered habit reversal training, Internet-delivered exposure and response prevention
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Karolinska Institutet