Clinical trials: Burn Injuries
Burns
ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
This is a randomized, within-subject controlled study to compare the clinical performance of the ReCell device when used as an adjunct to meshed skin graft in subjects requiring skin grafts for closure of burn injuries.
- Trial name
- NCT02380612
- Testing
- ReCell Treatment, Skin Graft
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Avita Medical
Burns Second Degree
Thermal Imaging and Pediatric Burns
The need to cover a burn with a skin graft is determined primarily by its depth. In fact only burns of the second deep degree or the third degree are likely to be grafted.
- Trial name
- FLIRPED (NCT03702972)
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burns, Pediatric ALL
Telemedicine Optimized Burn Intervention
Because burn patients and their caregivers often live long distances from regional burn centers, access to expert burn care is limited, resulting in a negative effect on adherence to treatment and a higher risk of wound…
- Trial name
- TOBI (NCT05019144)
- Testing
- Face-to-face burn care, Telemedicine enhanced burn care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Medical University of South Carolina
Burn
Feasibility Study: Enzymatic Debridement in Patients With Partial Thickness Burns
Burns represent one of the most severe and dreaded traumas. Burned and traumatized tissue is known as eschar. The dead eschar, if not removed, often becomes heavily contaminated and is the source of local and/or systemic…
- Trial name
- NCT00898521
- Testing
- DGD
- Where
- 2 sites in India, Israel
- Volunteers
- 36 people
- Sponsor
- MediWound Ltd
Burns, Respiratory Function Impaired
Inspiratory Muscle Training in Children With Chest Burn
8 weeks of inspiratory muscle training combined with a pulmonary rehabilitation program increases respiratory muscle strength, pulmonary function, functional capacity, and quality of life in chest burned children.
- Conditions
- Burns, Respiratory Function Impaired, Children
- Trial name
- chestburn (NCT05603507)
- Testing
- inspiratory muscle training, pulmonary rehabilitation
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Qassim University
Pediatric Burns
Silver in Partial Thickness Pediatric Burns
Most burns in children are due to scalds and with proper dressings will heal on their own without the need for surgery such as skin grafting.
- Trial name
- NCT06971562
- Testing
- Aquacel AG, Aquacel
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Burn Out, Addiction, Smartphone
Burnout, Covid 19, Smarthphone Addiction
We investigate burnout syndrome and smartphone addiction in healthcare workers, including doctors, nurses, medical secretaries, security guards, and cleaning staff, who have been actively working from the beginning of the…
- Trial name
- NCT05248217
- Testing
- healthcare workers
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Hypertrophic Scarring After Burn Injury
Effectiveness of Pressure Garment Therapy After Burns
Purpose - To determine the effectiveness of custom-fit pressure garment therapy in the prevention of hypertrophic scarring in healed burns. Background - Approximately one million people are burned each year in the United States.
- Trial name
- NCT01005732
- Testing
- Custom fabricated pressure garments
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Washington
Burn Wounds, Burn
The Effect of Hologram Application on Pain, Anxiety, and Fear Levels in Children During Burn Dressing
The process of dressing burn injuries has been shown to cause both physical and psychological difficulties. In children, this process is particularly associated with intense pain and anxiety.
- Trial name
- NCT06992895
- Testing
- The visual presentation utilizes a three-dimensional holographic fan device.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Split-thickness skin grafting (STSG) is one of the most commonly performed procedures to achieve wound closure. Most studies are concerned on improving the appearance of scars and shortening the healing time of the recipient…
- Trial name
- NCT06488612
- Testing
- Minced skin grafts for donor site
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pediatric Burns
Virtual Reality MObility for Burn Patients
Background In the acute phase, burn patients undergo several painful procedures. Pediatric burn care procedures conducted in hydrotherapy have been known to generate severe pain intensity and moderate to high levels of anxiety.
- Trial name
- VR-MOBILE (NCT04538573)
- Testing
- Virtual Reality Distraction, Standard Treatment
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adults and adolescents with partial deep dermal and full thickness burns.
- Trial name
- NCT03227146
- Testing
- EHSG-KF, STSG
- Where
- 6 sites in Italy, Netherlands and 1 more
- Volunteers
- 14 people
- Sponsor
- CUTISS AG
Burns, Sedation
Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients
Dexmedetomidine is a sedative drug approved for adult patients, intubated, in intensive care units. We are studying whether this drug is cardiovascularly safe in pediatric patients who have recently been burned.
- Trial name
- NCT00697788
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Burn Scar, Scar
Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars
This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment.
- Trial name
- SMOOTH (NCT04736251)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Naiem Moiemen
Burns
CONTINUED ACCESS PROTOCOL: Demonstration of the Safety and Effectiveness of ReCell® Combined With Meshed Skin Graft for Reduction of Donor Area in the Treatment of Acute Burn Injuries
The overall purpose of this is study to provide continued access to the ReCell device following completion of protocol CTP001-6, and allow for collection of supplementary clinical outcome data for the ReCell device when used as…
- Trial name
- NCT02994654
- Testing
- ReCell
- Where
- 6 sites in United States
- Volunteers
- 12 people
- Sponsor
- Avita Medical
Burns
Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group
The primary objective is to compare the effectiveness of treatment with Sulfamylon® solution as the initial topical moist dressing over meshed autografts following the initial graft procedure on preventing graft loss in a…
- Trial name
- NCT00634166
- Testing
- Sulfamylon® For 5 % Topical Solution, Topical Antimicrobial/Antifungal Medications
- Where
- 9 sites in United States
- Volunteers
- 220 people
- Sponsor
- Mylan Inc.
Insulin Resistance, Hypermetabolism
Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin
Massive pediatric burns are associated with a persistent and sustained hypermetabolic response characterized by elevated levels of circulating catecholamine's, cortisol, and glucagon's, which can cause extreme muscle wasting…
- Conditions
- Insulin Resistance, Hypermetabolism, Hyperglycemia
- Trial name
- NCT01666665
- Testing
- Metformin, Sugar pill
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Stress, Well-being
Leading Well-being and the Psychosocial Working Environment - A Cluster-randomized Waitlist Controlled Trial
The design comprises a cluster, randomized waitlist controlled design. The goal of the study is to prevent stress and burnout in middle managers and employees in a hospital setting.
- Conditions
- Stress, Well-being, Burn Out
- Trial name
- Matterhorn (NCT05623371)
- Testing
- Training leaders in leading well-being and the psychosocial working environment, The offer of a webinar and written material
- Where
- Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Burn Wound, Second- or Third-degree Burn
MSCs for the Treatment of Burn Wounds
The goal of this study is to evaluate the capacity of allogenic mesenchymal stromal cells form bone marrow (BM-MSC) or adipose tissue(Ad-MSC) to induce wound healing in patients with burn wounds.
- Trial name
- NCT06103409
- Testing
- Implantation of allogeneic MSCs on burn wounds
- Where
- Venezuela
- Volunteers
- 50 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Burn
Use of Amnion on Partial Thickness Burns
To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.
- Trial name
- Amnion (NCT00674999)
- Testing
- Amnion, Polysporin/Bacitracin/Mycostatin
- Sponsor
- The University of Texas Medical Branch, Galveston