Clinical trials: Burn Injuries
Burns
ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
This is a randomized, within-subject controlled study to compare the clinical performance of the ReCell device when used as an adjunct to meshed skin graft in subjects requiring skin grafts for closure of burn injuries.
- Trial name
- NCT02380612
- Testing
- ReCell Treatment, Skin Graft
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Avita Medical
Burns
Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns
The aim of this study is to compare Mepitel Ag to Triple antibiotic ointment impregnated Adaptic gauze when used with the soft cast technique to assess overall time to healing, yeast infection rate and parents perception of pain…
- Trial name
- NCT02681757
- Testing
- triple antibiotic ointment dressing, Mepitel Ag
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Retinal Light Damage, Photic Retinopathy
OCTA Evaluated the Efficacy of Glucocorticoid Retrobulbar Injection in Retinal Photo-injury
The goal of this retrospective observational study is to evaluate the effectiveness of retrobulbar glucocorticoid injection in patients with retinal photo-injury.
- Conditions
- Retinal Light Damage, Photic Retinopathy, Photic Maculopathy
- Trial name
- NCT07869511
- Testing
- retrobulbar injection of glucocorticoid
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burns, Respiratory Function Impaired
Inspiratory Muscle Training in Children With Chest Burn
8 weeks of inspiratory muscle training combined with a pulmonary rehabilitation program increases respiratory muscle strength, pulmonary function, functional capacity, and quality of life in chest burned children.
- Conditions
- Burns, Respiratory Function Impaired, Children
- Trial name
- chestburn (NCT05603507)
- Testing
- inspiratory muscle training, pulmonary rehabilitation
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Qassim University
Burns
Effect of Music Therapy on Families of Burn Patients
The purpose of this study is to investigate the efficacy of music therapy in assisting with the coping and adjustment of children of adults with major burns.
- Trial name
- MTS3 (NCT00824681)
- Testing
- Sound Of Family Together (S.O.F.T.) Music Program, Non-Therapy Related Activities (NTRA)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MetroHealth Medical Center
Burn Scar
Comparison of Length Gain Between Square Flap and Z-plasty in Post Burn Contracture Release
the purpose of this study is to compare the gain in length after postburn contracture release using two different techniques, the more commonly practised z - plasty and relatively newer technique, square flap
- Trial name
- NCT04690543
- Testing
- z-plasty, square flap
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Burn Out, Addiction, Smartphone
Burnout, Covid 19, Smarthphone Addiction
We investigate burnout syndrome and smartphone addiction in healthcare workers, including doctors, nurses, medical secretaries, security guards, and cleaning staff, who have been actively working from the beginning of the…
- Trial name
- NCT05248217
- Testing
- healthcare workers
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Burn
Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate
Major burn injury causes significant insulin resistance on glucose and protein metabolism that persists for up to 6 months after the acute injury This project proposes to answer the following questions: 1.
- Trial name
- NCT00732485
- Testing
- fenofibrate
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
CONTINUED ACCESS PROTOCOL: Demonstration of the Safety and Effectiveness of ReCell® Combined With Meshed Skin Graft for Reduction of Donor Area in the Treatment of Acute Burn Injuries
The overall purpose of this is study to provide continued access to the ReCell device following completion of protocol CTP001-6, and allow for collection of supplementary clinical outcome data for the ReCell device when used as…
- Trial name
- NCT02994654
- Testing
- ReCell
- Where
- 6 sites in United States
- Volunteers
- 12 people
- Sponsor
- Avita Medical
Limbal Stem Cell Deficiency, Stevens-johnson Syndrome
Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation
To investigate the effect of ocular surface reconstruction and assess the safety in cultivated oral mucosal epithelial cell sheet transplantation (COMET) regarding patients with cicatricial change of ocular surface.
- Conditions
- Limbal Stem Cell Deficiency, Stevens-johnson Syndrome, Ocular Cicatricial Pemphigoid, Chemical Burn
- Trial name
- NCT02149732
- Testing
- cultivated oral mucosal epithelial sheet transplantation
- Where
- 2 sites in South Korea
- Sponsor
- Seoul National University Hospital
Burns, Sedation
Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients
Dexmedetomidine is a sedative drug approved for adult patients, intubated, in intensive care units. We are studying whether this drug is cardiovascularly safe in pediatric patients who have recently been burned.
- Trial name
- NCT00697788
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Burns
A Postmarket Randomized Study of the Treatment of Superficial Partial-Thickness Burns Using Two Dressings
The purpose of this research study is to compare the rate of healing, the infection or complication rate, pain perception and scarring from burn injuries using two types of burn dressings.
- Trial name
- NCT01067729
- Testing
- AWBAT Wound Dressing, AWBAT™, Biobrane®
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Burns
Efficacy of a Fibrin Sealant in Burn Surgery
The purpose of this study is to determine the effectiveness of a fibrin glue in burn surgery with respect to hemostasis and skin graft fixation.
- Trial name
- NCT00181974
- Testing
- Tisseel Fibrin Sealant
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Burns
Evaluation of Hand Assessments in Children With Severe Hand Burns
This study is designed to see if some tests of hand movement, strength, and function are valid for children with burns.
- Trial name
- NCT00363675
- Testing
- Functional hand tests
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Massachusetts General Hospital
Second-degree Burn Wounds, Skin Graft Wounds
Efficacy of a Transparent Silicone Membrane With Physical Microstructure for Second-degree Burn Wounds and Skin Graft Wounds
The goal of this clinical trial is to comparison of physical microstructure-modified transparent silicone films and current conventional trauma dressings for second-degree burn wounds and post-skin graft wounds.The main question…
- Trial name
- NCT06170008
- Testing
- Physical microstructure-modified transparent silicone film sheet, Decellularized pig skin, Vaseline gauze
- Volunteers
- 40 people
- Sponsor
- Changhai Hospital
Burns, Acute Pain
VR for Burn Dressing Changes at Home
This study will evaluate the impact of our smartphone-based Virtual Reality Pain Alleviation Tool (VR-PAT) during the repeated at-home burn dressing changes of children (5-17 years) with a burn injury in comparison with a control…
- Conditions
- Burns, Acute Pain, Procedural Pain
- Trial name
- NCT04548635
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Nationwide Children's Hospital
Pain Management
Efficacy of Music Therapy Protocols for Burn Debridement
The purpose of this prospective, crossover randomized study is to explore the efficacy of two music therapy protocols on pain, anxiety, and muscle tension levels throughout the debridement process in individuals hospitalized with…
- Trial name
- MTS1 (NCT00822497)
- Testing
- Music-Based Imagery (MBI), Music Alternate Engagement (MAE)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- MetroHealth Medical Center
Full Thickness Burn
Permeaderm Versus Homograft for Full-thickness Burns
Frozen Human Cadaver Allograft (FHCA) is, nowadays, the gold standard for temporary coverage of excised full-thickness burns, but is also very expensive and requires additional personnel and major storage spaces in comparison to…
- Trial name
- NCT04673435
- Testing
- PermeaDerm for temporary coverage, FHCA for temporary coverage, PermeaDerm over autograft
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Pain, Burns
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial
Children with burn injuries experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Burns, Child, Anxiety
- Trial name
- DREAM-T (NCT02947243)
- Testing
- VR distraction via Oculus Rift, Morphine
- Where
- Canada
- Sponsor
- St. Justine's Hospital
Intubation; Difficult or Failed
Application of THRIVE in Burn Children With Suspected Difficult Airway
In order to improve intubation conditions in burn children, our aim is to investigate the efficacy of transnasal humidified rapid-insufflation ventilatory exchange technique（THRIVE) in children aged between 0 and 18 years who…
- Trial name
- NCT06459076
- Testing
- Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)
- Volunteers
- 120 people
- Sponsor
- Shuxiu Wang