Clinical trials: Burn Patients
Burns
An Investigation of Performance and Safety of the Wound Dressing FibDex in Patients With Superficial Dermal Burns
This is a prospective, randomised, open-label, within-patient controlled, non-inferiority clinical investigation of the nanofibrillar cellulose (NFC) wound dressing FibDex® for treatment of superficial dermal burns in paediatric…
- Trial name
- NCT05629091
- Testing
- FibDex, Epicite hydro, Epiprotect
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- UPM-Kymmene Corporation
Herpes Simplex
Antiviral Prophylaxis in a Burn Population
A prospective, randomized trial to calculate incidence of Herpes Simplex Virus in an in-patient burn population and determine efficacy of prophylactic antiviral therapy to prevent viral infection and/or reactivation.
- Trial name
- NCT02349828
- Testing
- Acyclovir
- Where
- United States
- Sponsor
- Southern Illinois University
Children, Acute Pain
Phoenixin and Pain in Pediatric Burn Patients
This prospective, controlled, observational study aims to investigate the relationship between phoenixin (PNX) levels and pain in pediatric burn patients.
- Conditions
- Children, Acute Pain, Burn Pain, Burn Degree Second
- Trial name
- NCT07858409
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Burns, Morality
Analysis and Accuracy of Mortality Prediction Scores
Patients admitted to the ICU in a tertiary burn centre in Kuwait were analysed using multiple mortality prediction scores. The accuracy of these scores were compared to each other to ascertain which prediction modality provides…
- Trial name
- NCT04737148
- Testing
- Mortality scores
- Where
- Kuwait
- Volunteers
- 211 people
- Sponsor
- Ministry of Health, Kuwait
Burns
Antioxidant Status During Burn Rehabilitation
It is believed that children with a prior history of significant burn injury continue to manifest low levels of antioxidants well into their convalescence.The purpose of this study is to examine malondialdehyde (an oxidative…
- Trial name
- NCT00536822
- Sponsor
- Shriners Hospitals for Children
Emergence Delirium in Pediatric Anesthesia
The Effect of Dormicum-Ketamine Versus Dexmedetomidine on Emergence Delirium During Deep Sedation in Paediatric Burn Patients
The aim of this study is to compare the effects of dormicum-ketamine versus dexmedetomidine on postoperative emergence delirium in pediatric patients undergoing deep sedation for burn-related procedures
- Trial name
- NCT07519863
- Testing
- Midazolam + Ketamine, Dexmedetomidine (DEX)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Burns Degree Second, Pediatric
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO).
- Trial name
- CHITAG (NCT06987981)
- Testing
- Chitosan-based dressing, Silver-based dressing
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Miloš Potkonjak
Microstomia
Efficacy of 3D-Printed Mouth Splints
The study will investigate the effectiveness of a 3D-printed mouth splint designed to increase dimensions of oral aperture and reduce disability associated with mouth contractures.
- Trial name
- 3DMS (NCT06801535)
- Testing
- Splint
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Second Degree Burns
Heparin for the Treatment of Burn Wound Pain
Pain Associated with partial thickness burns (PTB) is very severe and distressing for the patients.Topical conventional treatment of superficial PTB wounds includes application of polyfax skin ointment plus lignocain gel twice a…
- Trial name
- NCT02497326
- Testing
- Polyfax & Lignocain gel or silvazine cream, Topical Heparin, Tramadol
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- King Edward Medical University
Muscle Weakness, Late Effect of Burn
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
This study will measure efficacy of early in-patient exercise as an adjunct to current Standard of Care (SOC) for 96 patients in a multi-centre trial.
- Conditions
- Muscle Weakness, Late Effect of Burn, Muscle; Fatigue, Heart, Burn Rehabilitation
- Trial name
- MP-10 (NCT02739464)
- Testing
- Exercise + SOC PT/OT, SOC PT/OT
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Laser Burn
Comparison of Laser Speckle Contrast Imaging and Laser Doppler Imaging in Burn Patients
Timely and accurate estimation of the surface area and depth of a burn injury is essential for determining an appropriate treatment modality.
- Trial name
- COLA-B (NCT05037916)
- Testing
- laser speckle contrast imaging device
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maasstad Hospital
Burns
Determination of Nerve Growth Factor (NGF) Expression in Pediatric Patients With Severe Burns: a Pilot Study
The goal of this observational study is to determine the blood values of NGF in severely burned patients, to describe any changes over time and finally to correlate the expression of NGF to the severity of the burn.
- Trial name
- NCT05751174
- Testing
- pediatric patients affected by severe burns
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Burns
Effect of Nutritional Supplementation on Pediatric Burn Patients
This study will determine the effect of nutrition supplementation on blood protein levels in pediatric burn patients.
- Trial name
- NCT01464866
- Testing
- Nutritional Supplement, Hospital food
- Where
- 9 sites in Russia
- Volunteers
- 116 people
- Sponsor
- Abbott Nutrition
Acute Respiratory Distress Syndrome (ARDS)
Turning Ratios Into Prognosis: Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as Powerful Predictors of ARDS in Pediatric Burn Patients: A Prospective Evaluation
The aim of this study is to evaluate the role of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as predictors for development of ARDS in pediatric burn patients.
- Trial name
- NCT07414056
- Testing
- Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Partial-Thickness Burn, Thermal Burn
Silver Sulfadiazine With Hyaluronic Acid Versus Silver Sulfadiazine Alone in Partial-Thickness Burns
Partial-thickness burns are commonly treated with topical silver sulfadiazine; however, its use may delay epithelialization due to cytotoxic effects on regenerating cells.
- Trial name
- NCT07367087
- Testing
- Silver Sulfadiazine With Hyaluronic Acid, Silver Sulfadiazine
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dr Muhammad Naveed Shahzad
Burns
Organ Protective Effect of Cetirizine In Patients With Severe Burns
This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns.
- Trial name
- NCT06126991
- Testing
- Cetirizine, Midazolam and Fentanyl
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Ruijin Hospital
Wound Healing
Cell Suspension With Biologic Dressing for Burn Wounds
This study is a prospective, multicenter, real-world observational study. It aims to evaluate the effectiveness and safety of a combined therapy-autologous epidermal cell suspension followed by biological dressing (porcine…
- Trial name
- NCT07555418
- Testing
- Autologous Epidermal Cell Suspension
- Volunteers
- 386 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Burn Degree Second, Burn Degree Third
The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients
The Swisskera project is a multicenter follow-up study at the three Swiss burn centers evaluating long-term outcomes after burn wound coverage with lab-grown epithelial grafts, specifically cultured epithelial autograft (CEA)…
- Conditions
- Burn Degree Second, Burn Degree Third, Skin Transplantation, Full Thickness Skin Defects
- Trial name
- Swisskera (NCT07415577)
- Testing
- Standard of Care (SOC)
- Where
- 3 sites in Switzerland
- Volunteers
- 236 people
- Sponsor
- University Children's Hospital, Zurich
Burn
Vitamin E Supplementation in Burned Patients
A dietary antioxidant, alpha-tocopherol, will be used to potentially attenuate Vitamin E short- and long-term losses in plasma and adipose, reverse the oxidative stress of burn injury and, in the process, decrease the secondary…
- Trial name
- NCT01749371
- Testing
- Vitamin E
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns, Wounds
Kerlix Gauze Study in a Burn Trauma Unit and Its Effect on Healthcare Associated Infections in Burn Patients
The purpose of this study is to determine whether Kerlix AMD gauze will decrease the incidence of healthcare associated infections in burn patients.
- Trial name
- NCT00656708
- Testing
- Kerlix AMD gauze
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Lucy A Wibbenmeyer