Clinical trials: Burns
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Partial-thickness Burn
Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns
A randomized, controlled, 30-subject, within-subject trial for examining the effectiveness of KeraStat Gel, as opposed to the institutional standard of care, silver sulfadiazine, in improving cosmesis of the healed wound.
- Trial name
- NCT03564795
- Testing
- KeraStat Gel, Silver Sulfadiazine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- KeraNetics, LLC
Skin Wound, Burns
StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects
Autografting is a surgical procedure to transplant healthy skin (donor skin) from another part of the participant's own body (donor site) to the burned part. Autografting is the usual treatment for DPT burns.
- Conditions
- Skin Wound, Burns, Trauma-related Wound
- Trial name
- StrataSTEPS (NCT05517902)
- Testing
- StrataGraft
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Burns
Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two.
The goal of this comparative, interventional randomized controlled trial is to use albumin during resuscitation in pediatric burn patients on day 2, as it can reduce extravasation of fluids and decrease the overall fluid…
- Trial name
- NCT06224777
- Testing
- 5% Albumin (human) Solution, Paeds solution
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- King Edward Medical University
Pain, Acute
Virtual Reality Analgesia for Pediatric Burn Survivors
Many children with large severe burns report severe pain during burn wound cleaning. The current study explores whether adjunctive immersive Virtual Reality distraction may help reduce the intensity of pain experienced by…
- Trial name
- NCT03491657
- Testing
- virtual reality distraction (Yes VR), music distraction (No VR)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Lactobacillus GG Supplementation During Pediatric Burn Injuries
Critical illness and the therapies that accompany it are associated with a disruption in the ecological equilibrium of the GI tract that can ultimately lead to infection.
- Trial name
- NCT00220519
- Testing
- Lactobacillus GG
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Shriners Hospitals for Children
Deep Partial Thickness Burn
Efficacy and Safety Study of rhGM-CSF Gel to Treat Deep 2nd Thickness Burn
This was a multicenter, randomized, phase Ⅳ study, to investigate the extensive efficacy and safety of Recombinant Human Granulocyte/Macrophage Colony-stimulating Factor Hydro-gel for Topical Application (rhGM-CSF Gel) on deep…
- Trial name
- rhGM-CSF (NCT01785784)
- Testing
- rhGM-CSF Gel
- Volunteers
- 2,510 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Cyanide Poisoning
Hydroxycobalamin and Rural Emergency Medical Services Cyanide Exposure Patients: A Cost Analysis
The costs to a rural emergency medical services (EMS) system of a change from a traditional cyanide antidote kit to a kit containing hydroxocobalamin alone are currently unknown.
- Trial name
- NCT01656616
- Testing
- Cyanide antidote administration
- Where
- United States
- Sponsor
- MaineHealth
Wound Healing
Plasma Therapy for Scar Management
This study is a prospective, multicenter, real-world observational study. It aims to evaluate whether adding plasma device therapy to standard scar care is effective and safe for treating various types of scars, including…
- Trial name
- NCT07548593
- Testing
- Plasma Device
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Burned Children, Ceftazidime Treatment
Ceftazidime in Burn Children
Concentrations and effects of Ceftazidime in critically ill burn children are unpredictable and the risk of under-exposure may be associated with poor clinical outcomes.
- Trial name
- CEFTAZOPTIM (NCT03881800)
- Testing
- titration- blood sample
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burns, Nutritional Deficiency
Nutritional Intakes in Burn Patients Treated as Outpatients
Nutrition is a key component of burn care. The primary goal of nutrition is to provide adequate supply in macro and micronutrients that are necessary to maintain organ function but also to wound healing, infection control and…
- Trial name
- NCT03914560
- Testing
- Burn injury
- Where
- Belgium
- Volunteers
- 51 people
- Sponsor
- University of Liege
Burn
Altrazeal Range of Motion Study Comparing With Typical Carboxymethyl
The objective of this study is to evaluate the difference in joint range of motion of a new flexible hydrogel nanoparticle wound dressing compared to typical sodium carboxymethylcellulose dressing Aquacel AG for treatment of…
- Trial name
- ROM (NCT01062191)
- Testing
- Aquacel AG, typical carboxymethylcellulose dressing, Altrazeal Flexible Hydrogel Nanoparticle Wound Dressing
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- ULURU Inc.
Pain, Acute
Distraction as Treatment for Pain in Children in Resource-scarce Settings
Pain alleviation in pediatric patients can be challenging for medical professionals working in resource scarce settings due to limited availability of medication, monitoring equipment, or training in this field of expertise.
- Trial name
- DISTRACT (NCT06933303)
- Testing
- Distraction with kaleidoscope
- Where
- South Africa
- Volunteers
- 126 people
- Sponsor
- Vrinnevi Hospital
Second Degree Burn
Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®
The primary objective is to compare the incremental costs (direct and indirect) and benefits (healing outcomes, quality of life) of using foam silver dressing (Mepilex® Ag) to a Silver sulfadiazine 1% cream (Silvadene®) from the…
- Trial name
- NCT00742183
- Testing
- Mepilex, Silvadene
- Where
- 10 sites in United States
- Volunteers
- 100 people
- Sponsor
- Molnlycke Health Care AB
Burn Injury, Burns
Foreign-National Burn Patients in a Border-Region Burn Center
This retrospective cohort study will evaluate burn patients hospitalized and treated at the Burn Center of Gaziantep City Hospital between October 2023 and June 2026.
- Trial name
- NCT07673796
- Volunteers
- 1,400 people
- Sponsor
- Gaziantep City Hospital
Burns
Comparison of Effectiveness of Amniotic Membrane and Duoderm Dressings in Pediatric Burns
There is a difference in frequency of wound infection, mean pain score, mean of time for skin grafting and hospital stay in pediatric 2nd and 3rd degree burns, between amniotic membrane and duoderm dressings
- Trial name
- NCT04030754
- Testing
- amniotic membrane, duoderm dressing
- Where
- Pakistan
- Volunteers
- 172 people
- Sponsor
- King Edward Medical University
Limbal Stem Cell Deficiency Due to Ocular Burn
Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns
This is a multinational, multicentre, prospective, non-pharmacological follow-up study of the clinical trial HOLOCORE. All patients transplanted with Holoclar in the HOLOCORE clinical trial who consent to participate will be…
- Trial name
- HOLOCORE-FU (NCT03288844)
- Testing
- Ophthalmologic examinations, Digital pictures, QoL Questionnaires
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- Holostem s.r.l.
Burns
Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients
The purpose of this study is to determine whether either a peripheral nerve block under ultrasound (u/s) guidance of the lateral femoral cutaneous nerve (LFCN), versus an u/s guided block of the nerve followed by continuous…
- Trial name
- NCT01500655
- Testing
- Regional nerve block, Catheter
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Inhalation Anesthesia
Comparing Nebulized Ketamine,Nebulized Ketamine and Precedex and IM Ketamine for Analgesia in Pediatric Burn
The present study compares efficacy of nebulised ketamine and combination of nebulised dexmedetomidine and ketamine and intramuscular ketamine for procedural sedation and analgesia in pediatric burn injuries
- Trial name
- NCT07086690
- Testing
- Group (1): Patients will receive nebulized ketamine (2 mg/kg), Group (2): Patients will receive nebulized combination of dexmedetomidine and ketamine (1 μg/kg + 1 mg/kg), Patients will receive intramuscular ketamine (4 mg/kg, intramuscularly) 15 mins before starting the procedure.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Burn, Reconstructive Surgical Procedure
Evaluation Perioperative Nutrition on Donor Site Healing in Patients Undergoing Reconstructive Burn Surg
The investigators hope to learn if taking a nutrition drink for a short time after surgery for an elective reconstructive burn injury improves donor site healing, muscle mass and scar maturation time (the point at which the…
- Trial name
- NCT00539097
- Testing
- Juven (Ross Products) protein supplement
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children