Clinical trials: C Reactive Protein
Children
Children With Fever and Respiratory Symptoms at Out-of-hours Services in Norway
Viral self-limiting infections in respiratory organs among children are common in primary care. Serious infections have low prevalence and are challenging to distinguish from self-limiting infections.
- Trial name
- NCT02496559
- Testing
- Pre-consultation CRP
- Volunteers
- 401 people
- Sponsor
- NORCE Norwegian Research Centre AS
Acute Respiratory Infections (ARIs)
FebriDx® Pediatric Validation Study
The primary objective of this study is to determine performance characteristics of the FebriDx® test in differentiating bacterial from non-bacterial etiology among febrile pediatric patients (2-11 years) presenting to the…
- Trial name
- NCT07211997
- Testing
- FebriDx
- Where
- 10 sites in United States
- Volunteers
- 800 people
- Sponsor
- Lumos Diagnostics
Antibiotic Prescribing for Acute Respiratory-tract Infections
Effect of CRP and SAA Point-of-care Testing on Antibiotic Prescribing for Acute Respiratory-tract Infections
The study was a practical, cluster-randomized controlled trial to evaluate the impact of CRP and SAA point-of-care testing (CRP\&SAA POCT) on antibiotic prescribing in patients with acute respiratory-tract infections (ARI) at…
- Trial name
- NCT06568432
- Testing
- CRP+SAA POCT
- Where
- China
- Volunteers
- 35,108 people
- Sponsor
- Huazhong University of Science and Technology
Bacterial Infections, Viral Infection
The Rate of C-reactive Protein (CRP) Increase as a Marker for Bacterial Infections in Children
Fever is one of the most common problems in pediatrics. Differentiating between bacterial infections, that require antibiotic therapy, and viral infections that resolve on their own is an important challenge for physicians.
- Trial name
- CRPv (NCT01159470)
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Acute Appendicitis
Acute Appendicitis: The Influence of C-reactive Protein and Leucocytes on Clinical Decision-making
Aim: To investigate if the results of CRP and leucocytes had any positive or negative influence on the surgeon's decision-making when handling patients with suspected AA.
- Trial name
- NCT02304653
- Testing
- Clinical descision making
- Where
- Denmark
- Volunteers
- 226 people
- Sponsor
- Odense University Hospital
Dentoalveolar Abscess
C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection
C-reactive protein levels of patients with acute apical abscess are evaluated before and after root canal treatment
- Trial name
- NCT04684407
- Testing
- ROOT CANAL TREATMENT
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Neonatal Sepsis
Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis
To evaluate reliability of salivary C-reactive protein ,mean platelet volume , neutrophil -lymphocyte ratio , and platelet lymphocyte ratio in diagnosis of neonatal sepsis
- Trial name
- NCT04800445
- Testing
- Salivary CRP
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infective Endocarditis
Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes in Infective Endocaridtis
The investigators conduct a prospective observational study on consecutive patients being admitted to a tertiary care-centre with infective endocarditis.
- Trial name
- CRP-IE (NCT02466139)
- Volunteers
- 102 people
- Sponsor
- Government Medical College, Kozhikode
Coronary Artery Disease
C-Reactive Protein (CRP) Gene Variants and Coronary Artery Disease in a Chinese Han Population
The recognition of the association between circulating C-reactive protein (CRP) levels and risk of coronary heart disease (CHD) has led to an increased emphasis on CRP genetic effects on CRP level and CHD.
- Trial name
- CRP-Han (NCT00780221)
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Acute Lymphoblastic Leukemia
Systemic Inflammation Response Index and C-Reactive Protein to Albumin Ratio in Acute Lymphoblastic Leukemia
the goal of this observational study is Assesment of systemic inflammatory index (SII) , system inflammation response index (SIRI) and CRP Albumin ratio(CAR) as biomarkers for ALL prognosis.
- Trial name
- NCT06674850
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infection
Impact of Clinical Guidance & Point-of-care CRP in Children: the ARON Project
Impact of clinical guidance \& point-of-care CRP test in children: the ARON project Trial Design: multicentre, cluster-randomized, parallel group pragmatic trial Trial Participants and setting: Children aged 6 months to 12 years…
- Trial name
- ARON (NCT04470518)
- Testing
- diagnostic algorithm
- Where
- Belgium
- Volunteers
- 6,750 people
- Sponsor
- KU Leuven
Cancer, Leukemia
C-Reactive Protein as a Predictor of Stem Cell Transplant Complications
The purpose of this study is to determine if C-Reactive Protein levels are predictive for complications post transplant.
- Conditions
- Cancer, Leukemia, Stem Cell Transplantation
- Trial name
- NCT00179868
- Testing
- C-Reactive Protein levels
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Obstructive Sleep Apnea
Biomarkers in Obstructive Sleep Apnea Surgery
Recent years have witnessed major advances in the understanding of the hormonal, metabolic, and biochemical changes that occur in obstructive sleep apnea (OSA).
- Trial name
- NCT00507078
- Testing
- Surgical treatment for OSA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Fever Malaria
Clinical Evaluation of the STANDARD™ Q Malaria/CRP Duo Test
The aim of this study is to assess the clinical performance (sensitivity, specificity, positive and negative predictive values) of the STANDARD™ Q Malaria/CRP Duo Test when used by health care workers (HW) in a point of care…
- Trial name
- NCT04791800
- Testing
- Malaria/CRP combination test
- Where
- India
- Volunteers
- 1,808 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Small Bowel Crohn's Disease
Assessment of Capsule Endoscopy Scoring Index (CESI), Harvey-Bradshaw Index (HBI) and Biological Markers in Small Bowel Crohn's Disease (SBCD)
Background: Small bowel Crohn's disease (SBCD) is a chronic relapsing disease, and clinical presentation can vary considerably. Patients are frequently assessed by capsule endoscopy (CE), which enables direct visualization of…
- Trial name
- NCT01555437
- Volunteers
- 58 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Traumatic Brain Injury
The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)
There are no therapeutic agents that have been shown to improve outcomes from severe traumatic brain injury (TBI). Critical barriers to progress in developing treatments for severe TBI are the lack of: 1) monitoring biomarkers…
- Trial name
- NCT04855396
- Where
- 11 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- University of Michigan
Heart Transplant Failure, Periodontitis
Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients
Inflammation plays a key role in the deterioration of chronic heart transplants. Periodontal disease is not limited to the tooth-supporting structures - it also contributes to systemic inflammation.
- Conditions
- Heart Transplant Failure, Periodontitis, Crp
- Trial name
- NCT03671408
- Testing
- clinical measurements
- Volunteers
- 33 people
- Sponsor
- Baskent University
Respiratory Infections in Children
Improving Antibiotic Stewardship for Children With Respiratory Illness Presenting to Village Health Workers in Uganda
This is a stepped wedge, cluster randomized study of a clinical algorithm that includes point-of-care C-reactive protein testing to inform antibiotic treatment decisions by village health workers for children presenting with…
- Trial name
- STAR (NCT05294510)
- Testing
- STAR Sick Child Job Aid
- Where
- Uganda
- Volunteers
- 1,280 people
- Sponsor
- University of North Carolina, Chapel Hill
Subarachnoid Hemorrhage
Antiepileptic Drugs and Vascular Risk Markers
The purpose of this study is to determine if certain seizure medications raise levels of cholesterol and other blood components which could increase the risk of heart attacks and strokes.
- Trial name
- NCT00774306
- Testing
- phenytoin, valproate, levetiracetam
- Volunteers
- 52 people
- Sponsor
- Thomas Jefferson University
Fever
The Impact of C-reactive Protein Testing
PRIMARY OBJECTIVE To assess the impact of C-reactive protein (CRP) Point-of-care (POC) testing on health care worker prescribing behaviour in patients presenting to primary healthcare centres with an acute fever or recent history…
- Trial name
- NCT02758821
- Testing
- No CRP will be measured onsite, CRP cut-off of 20mg/L., CRP cut-off of 40mg/L.
- Where
- Thailand
- Volunteers
- 2,410 people
- Sponsor
- University of Oxford