Clinical trials: CDH
Hernia, Diaphragmatic, Hypertension, Pulmonary
Chronic Sildenafil for Severe Diaphragmatic Hernia
The purpose of this study is to test if sildenafil is effective in the treatment of infants with severe congenital diaphragmatic hernia (determined by the presence of prolonged pulmonary hypertension or prolonged oxygen…
- Conditions
- Hernia, Diaphragmatic, Hypertension, Pulmonary, Hypoplasia, Pulmonary
- Trial name
- NCT00133679
- Testing
- sildenafil
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Congenital Diaphragmatic Hernia
CDH - Optimisation of Neonatal Ventilation
To determine the appropriate volume (size) of ventilator breath during volume-targetted ventilation for infants born with congenital diaphragmatic hernia.
- Trial name
- CDH-ONV (NCT02849054)
- Testing
- Measurement of PTPdi, TTV at 4ml/kg, TTV at 5ml/kg
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College London
Acetabular Dysplasia
Three Novel Radiological Indicators for Diagnosis of Adult Acetabular Dysplasia
Acetabular dysplasia often accompanies by acetabular bone hyperplasia and osteonecrosis of the femoral head. These pathological changes can alter the position of the center of the femoral head.
- Trial name
- NCT03541122
- Testing
- pelvic X-ray examinations
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hebei Medical University Third Hospital
Developmental Dysplasia of the Hip
Effectiveness of Cotton vs. Waterproof Cast Padding
This study aims to: 1) investigate the effectiveness of waterproof spica cast using Delta-Dry® Pantaloon and cast padding (BSN medical, USA) versus standard gortex pantaloon with cotton cast padding in maintaining the femur…
- Trial name
- NCT03859232
- Testing
- Delta Dry® Waterproof Pantaloon, Cotton Padding
- Where
- United States
- Sponsor
- Baylor College of Medicine
Congenital Diaphragmatic Hernia
Type of Material in Repair of Congenital Diaphragmatic Hernia
The objective of this study is to evaluate the use of 2 different types of biosynthetic material for the repair of congenital diaphragmatic hernia.
- Trial name
- NCT00257946
- Testing
- Repair of CDH w/SIS Gold, Repair of CDH w/Alloderm
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Mercy Hospital Kansas City
Orthopedic Disorder
End Button Tenodesis in Failed Developmental Dysplasia of the Hip Surgery
Adequate growth and development of the hip depends on two main factors: concentric positioning of femoral head into the acetabular cavity and adequate balance in growth between tri-radiate and acetabular cartilage.
- Trial name
- NCT05603858
- Testing
- Tenodesis by end button
- Volunteers
- 3 people
- Sponsor
- Al-Azhar University
Congenital Diaphragmatic Hernia
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) occurs when the diaphragm, the muscle that separates the chest cavity from the abdominal cavity, does not form properly.
- Trial name
- NCT01098929
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Congenital Hip Dysplasia
Early Abduction Splintage on Stable Hips in Infants With Developmental Dysplasia of the Hip
The aim of this study is to prove the improvement of pubo-femoral distance by early abduction splintage in one-month-old infants with developmental dysplasia of the hip (with a clinical stable hip but an abnormal hip…
- Trial name
- BBH (NCT02885831)
- Testing
- Abduction splintage
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Brest
Developmental Dysplasia of the Hip
Selective Ultrasound Screening for DDH 1991-2006
Early treatment is considered essential for developmental dysplasia of the hip (DDH), but the choice of screening strategy is debated. The investigators evaluated the effect of a selective ultrasound (US) screening programme.
- Trial name
- NCT01866527
- Where
- Norway
- Volunteers
- 81,564 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Congenital Diaphragmatic Hernia
Engagement in Physical Activities and Sports in Adolescents With Diaphragmatic Hernia
The objective is to understand how a population of adolescents - who have undergone diaphragm surgery within their first month of life (i.e.
- Trial name
- CHASAM (NCT05666986)
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Dysplasia; Hip
Spica Cast Duration for DDH
This study looks at treatment for developmental dysplasia of the hip (DDH), a condition where there is abnormal development of a child's hip joint.
- Trial name
- NCT06204068
- Testing
- Spica cast, Rhino brace
- Where
- United States
- Sponsor
- Yale University
Congenital Diaphragmatic Hernia
Airway Inflammation in Congenital Diaphragmatic Hernia Patients
We propose to examine Congenital Diaphragmatic Hernia (CDH) patients for evidence of airway inflammation as a first step to characterize the reported bronchodilator responsiveness.
- Trial name
- NCT02453750
- Testing
- Hypersaline, Bronchodilator Response
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- The Hospital for Sick Children
Developmental Dysplasia of the Hip
Do All Patients With Congenital Hip Dysplasia Corrected Operatively Need Physiotherapy
Developmental Dysplasia of the Hip (DDH) is a common condition among young children that could range in severity. in most sever cases, surgical intervention is the best choice to correct the hip abnormality with the aim of…
- Trial name
- NCT05238935
- Testing
- prescribed physiotherapy course
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Ministry of Health, Kuwait
Hip Dysplasia, Developmental
Efficacy Study of DeepDDH System in Screening Infants with Developmental Dysplasia of the Hip (DDH)
To ascertain the efficacy of the DeepDDH system, a deep learning framework, in enhancing diagnostic accuracy and curtailing follow-up intervals for infants undergoing screening for developmental dysplasia of the hip (DDH), the…
- Trial name
- NCT06765525
- Testing
- Junior sonographer measurement of DDH, Senior sonographer measurement of DDH, Automated annotation of the DDH measurement through deep learning
- Where
- China
- Volunteers
- 1,976 people
- Sponsor
- RenJi Hospital
Orthopedic Disorder
Developmental Hip Dysplasia by Ultrasonographic Screening of Asymptomatic Infants at Assiut University Hospital
Developmental dysplasia of the hip (DDH), formerly known as congenital dislocation of the hip, comprises a spectrum of abnormalities that include abnormal acetabular shape (dysplasia) and malposition of the femoral head.
- Trial name
- NCT03476915
- Testing
- ultrasound examination of the hip joint
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Assiut University
Developmental Dysplasia of the Hip (DDH)
Level of Iliopsoas Tenotomy in DDH Surgery
The goal of this clinical trial is to compare the postoperative clinical outcome of iliopsoas tenotomy in open reduction operation for developmental dysplasia of the hip.
- Trial name
- NCT06742749
- Testing
- Proximal level, Distal level
- Where
- Iraq
- Volunteers
- 54 people
- Sponsor
- University of Duhok
Congenital Hip Dysplasia
Pericapsular Nerve Group (PENG) Block for Congenital Hip Dislocation Surgery
Developmental dysplasia of the hip (DDH) is one of the major disorder of the pediatric population with an incidence of 3 to 5 per 1000 children.
- Trial name
- NCT04212039
- Testing
- Saline Solution, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Premature Baby, Pulmonary Hypertension of Newborn
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
This study aims to improve how neonatologists check the heart function of newborn babies, especially those who are sick. While standard heart ultrasound scans are useful, a more advanced and sensitive technique called 2D speckle…
- Conditions
- Premature Baby, Pulmonary Hypertension of Newborn, Hypoxic Ischaemic Encephalopathy (HIE), Congenital Diaphragmatic Hernia
- Trial name
- NCT07364682
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Developmental Dysplasia of the Hip (DDH)
Universal Ultrasound-screening for Developmental Dysplasia of the Hip in Newborn
All newborn from the period 12.1988 to 31.12.2006 During the two last decades, hip ultrasound has gained acceptance as an accurate screening test for developmental dysplasia of the hip (DDH) and for monitoring the development and…
- Trial name
- NCT01053299
- Testing
- open, prospective cohort-study
- Where
- Norway
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- Vestre VikenHF Kongsberg Sykehus
Developmental Dysplasia of the Hip (DDH)
Evaluation of a Software Application for Assessment of Developmental Dysplasia of the Hip
The goal of this prospective, multicentre clinical investigation is to evaluate whether an artificial intelligence (AI)-supported software application can assist clinicians in the diagnostic assessment of developmental dysplasia…
- Trial name
- EPA-DDH (NCT07488260)
- Testing
- AI-supported hip ultrasound analysis
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pentacomp Systemy Informatyczne S.A