Clinical trials: CHD
CHD - Congenital Heart Disease
Home-based Cardiovascular Rehabilitation in Young Patients With Congenital Heart Disease: the "Muscle Your Heart" Program
Standard cardiovascular rehabilitation is performed in a medical care and rehabilitation centre. However, it may not be adapted to the patient's profile and there are few medical care and rehabilitation centres specialized in…
- Trial name
- Muscletoncoeur (NCT07115589)
- Testing
- Muscle Your Heart home-based program
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Cardiovascular Diseases, Heart Diseases
Social Support and CHD Risk Factors--A Community Study
To examine the mechanism through which social support affects morbidity and mortality from coronary heart disease.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005343
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
Hypothyroidism, CHD
Hypothyroidism With Congenital Heart Disease (CHD)
Congenital hypothyroidism is one of the most preventable causes of neurocognitive impairment because early treatment is possible in neonates. The thyroid hormone is important for normal growth and development in infancy.
- Trial name
- NCT03496363
- Testing
- TSH , T4
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pulmonary Arterial Hypertension
Assessmet of Patients With PAH Right Ventricular Volume
The primary endpoint of this study is the percent difference between the VentriPoint Medical System (VMS) and cMRI for estimating the end diastolic and end systolic right ventricular volumes (RVEDV and RVESV) in subjects with…
- Trial name
- NCT01557582
- Testing
- Ventripoint Medical System
- Where
- 7 sites in United States, Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VentriPoint Diagnostics Ltd.
Congenital Heart Disease
Online Support 4 CHD Kids & Caregivers
This study will evaluate a virtual mental health parenting stepped-care intervention (I-InTERACT-North) to determine if the program works to improve positive parenting skills and child behaviour among families with children born…
- Trial name
- NCT06075251
- Testing
- I-InTERACT-North
- Where
- Canada
- Volunteers
- 382 people
- Sponsor
- The Hospital for Sick Children
Congenital Heart Disease, Infant Development
SNOO Smart Sleeper for Infants With CHD
Study Title The SSSH Study: SNOO Smart Sleeper Use in Post-Operative Infants with Congenital Heart Disease is a single site, cross-sectional, feasibility study of an infant smart sleeper.
- Conditions
- Congenital Heart Disease, Infant Development, Technology
- Trial name
- SHHH's (NCT04534335)
- Testing
- SNOO Smart Sleep from Happiest Baby, Inc
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Children's Mercy Hospital Kansas City
Cardiovascular Diseases, Coronary Disease
Epidemiology of Acute Phase Protein and CHD
To use the Multiple Risk Factor Intervention Trial (MRFIT) stored serum bank to do nested case-control studies of various serum risk factors in coronary heart disease incidence and mortality.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Atherosclerosis
- Trial name
- NCT00005371
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease (CHD), Chromosomal Abnormalities
Chromosomal Abnormalities in Patients With Congenital Heart Disease at Assiut University Children's Hospital
Congenital heart disease (CHD) is one of the most common birth defects and an important cause of infant morbidity and mortality.
- Trial name
- NCT07204509
- Testing
- Conventional Karyotyping
- Volunteers
- 138 people
- Sponsor
- Assiut University
Congenital Heart Disease, SRV Dependent
Intramyocardial Injection of Autologous UCB-MNC During Fontan Surgery for SRV Dependent CHD
Researchers want to better understand what happens to the heart when the autologous (from one's own body) stem cells are injected directly into muscle of the right side of the heart during the Fontan (Stage III) surgery.
- Trial name
- NCT04907526
- Testing
- Autologous mononuclear cells
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Timothy J Nelson, MD, PhD
Congenital Heart Disease (CHD), Structural Heart Disease
Artificial Intelligence-assisted Diagnosis
This study aims to investigate whether an AI-assisted decision support can improve the diagnosis of congenital heart diseases on Chest X-ray.
- Trial name
- AID (NCT06783933)
- Testing
- surgical or interventional validation
- Where
- China
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Congenital Heart Disease (CHD), Preschool Children
Feasibility Study of Home Cardiac Rehabilitation Program for Postoperative Children With Congenital Heart Disease
This single-arm feasibility study will pilot a home-based cardiac rehabilitation program for preschool children (aged 3 to 7 years) who have undergone corrective surgery for congenital heart disease.
- Conditions
- Congenital Heart Disease (CHD), Preschool Children, Rehabilitation
- Trial name
- NCT07055347
- Testing
- Comprehensive Home-based Cardiac Rehabilitation Program for Postoperative Congenital Heart Disease Patients and Their Caregivers
- Volunteers
- 5 people
- Sponsor
- Sun Yat-sen University
Enterocolitis, Necrotizing, Congenital Heart Disease
Utility of Bowel Ultrasound in Diagnosing Necrotizing Eneterocolitis in Congenital Heart Disease
To evaluate the feasibility of performing a randomized pilot control trial of two diagnostic screening strategies for necrotizing enterocolitis in patients with congenital heart disease.
- Trial name
- NCT03142685
- Testing
- Bowel Ultrasound
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Congenital Heart Disease, Psychological Well-being
The Living Experience of Hong Kong Chinese Adolescents With CHD.
This study aims to explore the impacts of CHD and its limitations on adolescents and the living experience of adolescents living with CHD.
- Conditions
- Congenital Heart Disease, Psychological Well-being, Quality of Life, Adolescent
- Trial name
- NCT03677232
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Congenital Heart Disease (CHD)
Biventricular Pacing in Children With Congenital Heart Disease
Surgery with cardiopulmonary bypass (CPB) for congenital heart disease (CHD) causes low cardiac index (CI). With the increasing success of surgery for CHD, mortality has decreased and emphasis has shifted to post-operative…
- Trial name
- NCT02644824
- Testing
- Biventricular Pacing (BiVp)
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- The Hospital for Sick Children
CHD - Coronary Heart Disease, CVD - Cerebrovascular Disease
Meta-analysis of Fruit and Vegetable Sources and Cardiovascular Outcomes
Fruit and vegetables are a cornerstone of healthy dietary patterns and dietary guidelines worldwide. The supporting evidence, however, is largely derived from observational studies of protective associations with cardiovascular…
- Conditions
- CHD - Coronary Heart Disease, CVD - Cerebrovascular Disease, Stroke
- Trial name
- NCT03394339
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Congenital Heart Disease (CHD)
Growth in Infants With Congenital Heart Disease at AUCH
Children with congenital heart disease (CHD) often experience growth problems. This study aims to assess and compare the growth (weight, height, head circumference) of infants and children with CHD against the expected growth…
- Trial name
- CHD-Growth (NCT07373873)
- Where
- 2 sites in Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
Genetics
A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study
Studies have shown that there is a significant association between serum bilirubin concentrations and risk of coronary artery disease (CAD).
- Trial name
- NCT00340509
- Where
- United States
- Volunteers
- 1,888 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease, Fetal Heart Disorder
Perinatal Cardiology: Bridging Obstetric and Neonatal Care in CHD
This prospective observational study aims to evaluate the agreement between prenatal fetal echocardiographic diagnoses and postnatal diagnoses of congenital heart disease, and to assess the impact of prenatal diagnosis status on…
- Conditions
- Congenital Heart Disease, Fetal Heart Disorder, Neonatal Disease, Fetal Disease
- Trial name
- NCT07820163
- Volunteers
- 115 people
- Sponsor
- Assiut University
ADHD, ASD
Cognitive Rehabilitation (Mega Team) and Its Effects on Emotional and Behavioral Regulation in ADHD, ASD, and CHD
Children with disorders that impact neurodevelopment often have difficulties with executive functions and regulating emotions. Cognitive-based video game training has been shown to improve outcomes, however, this training has…
- Conditions
- ADHD, ASD, CHD - Congenital Heart Disease
- Trial name
- NCT03502239
- Testing
- Mega Team - video game
- Where
- Canada
- Volunteers
- 440 people
- Sponsor
- The Hospital for Sick Children