Clinical trials: CONTROL Condition
Osteo Arthritis of the Knee, Genu Varum
Kinematic vs Mechanical Alignment in High Tibial Osteotomy
To compare between kinematic and mechanichal alignment after High Tibial Osteotomy (clinically and radiologically)
- Trial name
- NCT07551089
- Testing
- high tibial osteotomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Type 1 Diabetes (T1D)
PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study
This Phase 3, multicenter, randomized, double-blind, placebo-controlled study will evaluate the efficacy, safety, and tolerability of SAB-142, a fully human anti-thymocyte globulin (h-ATG), in participants aged 5 to 40 years with…
- Trial name
- PRISE-hATG (NCT07670650)
- Testing
- SAB-142
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of Florida
Diphtheria, Tetanus
Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age
This is a phase II, randomized, double-blind, active-controlled, parallel-group, multicenter study to evaluate the immunogenicity and safety of DTaP-HepB-IPV-Hib hexavalent vaccine LR20062 in healthy infants as primary series at…
- Conditions
- Diphtheria, Tetanus, Pertussis, Hepatitis B
- Trial name
- NCT06618196
- Testing
- LR20062, DTaP-HepB-IPV-Hib vaccine
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- LG Chem
Milk Allergy, Cow's, Food Allergy in Children
Oral Immunotherapy for Children With Cow's Milk Allergy
This clinical trial aims to investigate if oral immunotherapy can help children with cow's milk allergy tolerate cow's milk. Children aged 6-18 months can take part in the trial.
- Conditions
- Milk Allergy, Cow's, Food Allergy in Children, Food Allergies
- Trial name
- NCT07768696
- Testing
- Oral immunotherapy with cow's milk
- Where
- 5 sites in Denmark
- Volunteers
- 56 people
- Sponsor
- Laura Ozer Kettner
Developmental Dysplasia of the Hip
Evaluation of Aid to Diagnosis for Congenital Dysplasia of the Hip in General Practice
Developmental dysplasia of the hip (DDH) is one of the most common inborn diseases. Early diagnosis of this condition is very important and it can be harmful both to miss DDH and label normal infants as having DDH.
- Trial name
- HipDyS (NCT04101903)
- Testing
- The 6-week Hip Checklist
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Attention Deficit Disorder With Hyperactivity
Extra Time on Brazilian College Level Exam for Students With and Without ADHD
Standardized tests such as the Scholastic Aptitude Test (SAT) and the brazilian National High School Exam (ENEM) give more time for students with Attention Deficit and Hyperactivity Disorders (ADHD) to complete the exam.
- Trial name
- NCT06063382
- Testing
- Extended time 25%, Extended time 50%
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Behçet Disease
Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease
The aim of this study is to estimate the efficacy of apremilast compared to placebo in the treatment of oral ulcers in pediatric participants from 2 to < 18 years of age with oral ulcers associated with Behçet's disease (BD)…
- Trial name
- BEAN (NCT04528082)
- Testing
- Apremilast
- Where
- 27 sites in France, Greece and 6 more
- Volunteers
- 60 people
- Sponsor
- Amgen
Oral Lichen Planus
Effect of Adjunctive Systemic Vitamin E on Clinical Parameters and Salivary Total Antioxidant Capacity in Symptomatic Oral Lichen Planus Patients: Randomized-controlled Clinical Trial
Treatment of oral lichen planus is challenging. Diverse therapeutic modalities have been suggested, but a permanent cure is not yet available.
- Trial name
- NCT04126720
- Testing
- topical corticosteroids and vitamin E suplements
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Epidemic Meningitis, Meningococcal Vaccines
Phase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 6-11 Months
The goal of this clinical trial is to evaluate the immunogenicity, safety, and persistence of the immune response of a group ACYW135 meningococcal conjugate vaccine in healthy children aged 6 to 11 months.
- Trial name
- NCT07505823
- Testing
- experimental vaccine, Active Comparator vaccine
- Where
- 2 sites in China
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Spinal Cord Injuries
Evaluation of Sensory-motor Response to Low-level Laser Therapy for the Treatment of Spinal Injuries
Spinal cord injuries have become increasingly frequent due mainly to the increase in urban violence. The growing number of automobile collisions and violence-related events merits particular attention, as such occurrences can…
- Trial name
- NCT03031223
- Testing
- low-level laser therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Childhood Cancer
Motivation Program for Children With Cancer
Purpose: To determine the effectiveness of the technology-based motivation program implemented with children with cancer diagnosis and their primary caregivers.
- Trial name
- NCT05982379
- Testing
- Technology Based Motivation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Zeynep Kisecik Şengül
Intra-abdominal Abscess
Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study
The objective of this study is to establish the efficacy of tPA when used in pediatric intra-abdominal abscesses immediately after percutaneous drainage, irrespective of the ultrasound appearance or consistency of the drained…
- Trial name
- NCT01576679
- Testing
- Cathflo (Alteplase), Saline
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- The Hospital for Sick Children
Autism
Secretin for the Treatment of Autism
Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication.
- Trial name
- NCT00065962
- Testing
- secretin, synthetic porcine, secretin, biologically derived porcine
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Periapical Periodontitis
Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
To compare the dental survival in a period of one year of mature permanent teeth with apical lesion following the administration of encapsulated Mesenchymal Stem Cells under a regenerative endodontic procedure and a conventional…
- Trial name
- RanoKure (NCT03102879)
- Testing
- Regenerative Endodontic Procedure, Conventional Root Canal Treatment
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidad de los Andes, Chile
Stickler Syndrome
Scleral Buckling for Retinal Detachment Prevention in Genetically Confirmed Stickler Syndrome
The purpose of this study is to determine whether a scleral buckling surgical procedure performed on fellow eyes of patients with genetically confirmed Stickler syndrome can prevent the occurrence retinal detachment and/or severe…
- Trial name
- STL-DR-PREV (NCT04465188)
- Testing
- Encircling scleral buckle surgical procedure
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Feeding; Difficult, Newborn
Effect of SINC Feeding Protocol on Weight Gain, Transition to Oral Feeding and the Length of Hospitalization
Feeding is one of the most common problems encountered by preterm infants. Besides, effective and safe feeding is one of the important discharge criteria.
- Trial name
- NCT03371927
- Testing
- SINC Feeding Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cerebral Palsy (CP), Balance
The Effect of Kinesiologic Taping on Trunk Control and Balance in Children With Cerebral Palsy
Title: Effects of Kinesiology Taping on Motor Function, Balance, and Spasticity in Children with Hemiplegic and Diplegic Cerebral Palsy: A Four-Week Study Study Type: Interventional (Clinical Trial) Study Design: Single-group…
- Conditions
- Cerebral Palsy (CP), Balance, Kinesiology Taping, Spasticity
- Trial name
- NCT07188961
- Testing
- kinesiologic taping
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Rumeli University
Upper Respiratory Tract Infections, Perioperative Respiratory Complications
Interest of Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia
The goal of this clinical trial is to determine whether intravenous (IV) lidocaine reduces the incidence of perioperative respiratory complications (PRCs) in children with upper respiratory tract infections undergoing general…
- Trial name
- NCT06584461
- Testing
- Lidocaine (drug)
- Where
- Tunisia
- Volunteers
- 102 people
- Sponsor
- Tunis University
Attention Deficit Hyperactivity Disorder (ADHD)
Safety and Efficacy Study of SHP465 in Children and Adolescents Aged 6-17 Years With Attention-Deficit Hyperactivity Disorder (ADHD)
The study is designed to evaluate the efficacy and safety of SHP465 in the treatment of ADHD in children and adolescents (aged 6-17 years).
- Trial name
- NCT02466425
- Testing
- SHP465
- Where
- 36 sites in United States
- Volunteers
- 264 people
- Sponsor
- Shire
Asthma
Study of the Effect of Mometasone Furoate/Formoterol (MF/F), Montelukast and Beclomethasone Dipropionate (BDP) on Plasma Cortisol Levels of Children 5-11 Years Old With Persistent Asthma (P05574)
The purpose of this study is to assess the effect of one of five possible study medications used in the treatment of asthma on blood plasma cortisol levels in children aged 5-11 years with persistent asthma.
- Trial name
- NCT01615874
- Testing
- MF/F Metered Dose Inhaler (MDI) 25/5 mcg, MF/F MDI 50/5 mcg, MF/F MDI 100/5 mcg
- Sponsor
- Organon and Co
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