Clinical trials: CONTROL Condition
Colorectal Cancer, Breast Cancer
Case Control Study to Identify Modifiable Risk Factors for Colorectal and Breast Cancer in Nigeria
This project is a case-control study which seeks to identify modifiable risk factors for breast and colorectal cancer in Nigeria.
- Trial name
- NCT05044689
- Testing
- Questionnaire, Bioimpedance/Body Composition Unit
- Where
- Nigeria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Hypothalamic Obesity
A Study of Octreotide Depot vs Saline Control in Pediatric Hypothalamic Obesity Patients
The extension protocol is designed to allow those patients randomized to placebo in the core portion of the protocol to receive a 6 month treatment of open label octreotide and allow those patients randomized to octreotide who…
- Trial name
- NCT00171613
- Testing
- Octreotide
- Volunteers
- 32 people
- Sponsor
- Novartis
Schizophrenia
Relapse Prevention in First Episode Schizophrenia: a 5 Year Trial
Objective: to evaluate the effectiveness of specialised and sustained intervention with or without parent groups during the initial phase of schizophrenia or related disorders on relapse prevention Methods: A three conditions…
- Trial name
- NCT01936220
- Testing
- Continuity of specialized care, Parent groups combined with Continuity of Specialized care, Discontinuity of care, non specialised care
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
COVID-19
A 2nd Generation E1/E2B/E3-Deleted Adenoviral COVID-19 Vaccine: The TCELL VACCINE TRIAL
This is a phase 2/3, multicenter, randomized, placebo-controlled, observer-blind study assessing the safety, tolerability, immunogenicity, and efficacy of prophylactic hAd5-S-Fusion+N-ETSD against COVID-19.
- Trial name
- NCT06022224
- Testing
- hAd5-S-Fusion+N-ETSD
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- ImmunityBio, Inc.
Hypothermia
Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy
Controlled Hypothermia has become the standard of care for neonates with moderate to severe HIE. Ampicillin and aminoglycosides are drugs that are universally used for the treatment of suspected neonatal sepsis, which may or may…
- Trial name
- NCT03129620
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Drexel University
Reproductive Health, Sexual Health
Estimating the Impact of Sexuality Education and Mobile Health Services on Reproductive Health and Empowerment Among Adolescents in Sierra Leone for the Family Planning Impact Lab
The goal of this randomized controlled trial is to learn if comprehensive sexuality education (CSE) and access to mobile sexual and reproductive health (SRH) services in secondary schools can improve short- and long-term health…
- Conditions
- Reproductive Health, Sexual Health, Contraception Behavior, Pregnancy (Unwanted)
- Trial name
- REACH (NCT07860723)
- Testing
- Comprehensive Sexuality Education, Mobile SRH services
- Where
- Sierra Leone
- Volunteers
- 5,300 people, healthy volunteers welcome
- Sponsor
- Guttmacher Institute
Hidradenitis Suppurativa
Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa
The purpose of this research study is to further evaluate the efficacy of two treatment regimens for the treatment of hidradenitis suppurativa. This is a randomized controlled study.
- Trial name
- NCT01063270
- Testing
- Clindamycin & Rifampin, Clindamycin + Rifampin along with NdYag Laser treatment
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Henry Ford Health System
Sexually Transmitted Infections
STI/HIV Prevention Intervention for Adolescents in Singapore
A randomized controlled trial conducted on 688 sexually experienced adolescents, with 337 participants assigned to the routine program, and 351 to the new intervention developed from an assessment of their needs.
- Trial name
- NCT02461940
- Testing
- Adolescent Behavioral Intervention
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Cesarean Wound Disruption With Postnatal Complication
Impact of Preoperative Bathing on Post Caesarean Section Surgical Site Infection
Surgical site infection (SSI) is the commonest hospital-acquired infection globally, and prevalence is much higher in the low-income countries. Caesarean delivery carries a 5-20 fold risk for developing postpartum sepsis.
- Trial name
- SSI-MUST (NCT03544710)
- Testing
- preoperative bathing with antiseptic
- Where
- Uganda
- Volunteers
- 96 people
- Sponsor
- Mbarara University of Science and Technology
Muscle Cramp, Liver Cirrhosis
A Study Evaluating the Efficacy and Safety of Pregabalin Against Frequent Muscle Cramp in Patients With Liver Cirrhosis
Muscle cramp is defined as a paroxysmal, involuntary, and painful contraction of skeletal muscle. Cirrhotic patients can encounter with muscle cramp frequently, which might be associated with poor quality of life.
- Trial name
- NCT01271660
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Boramae Hospital
Hemophilia A
Low Dose Emicizumab vs Low Dose Factor VIII in Prophylaxis in Hemophilia A Patients
Low dose factor VIII prophylaxis is practiced around the world. Role of standard dose Emicizumab prophylaxis is well established. Emicizumab is an expensive drug.
- Trial name
- AFEEL (NCT06938659)
- Testing
- Emicizumab Injection, Factor VIII (FVIII)
- Where
- Bangladesh
- Volunteers
- 20 people
- Sponsor
- Dhaka Medical College
Postoperative Care/Methods, Drainage/Methods
The Effect of Manual Lymphatic Drainage on Swelling After Orthognathic Surgery - a Qualitative and 3D Facial Analysis.
Introduction / background Orthognathic surgery is an operation in which one or both jaws are fixed in a more favorable position performed by an osteotomy.
- Conditions
- Postoperative Care/Methods, Drainage/Methods, Edema/Prevention & Control, Orthognathic Surgical Procedures/Adverse Effects
- Trial name
- NCT03682159
- Testing
- manual lymphatic drainage
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Dermatophyte Infection, Terbinafine Adverse Reaction
Comparison of Efficacy of Double Dose Oral Terbinafine Vs Itraconazole in Treatment of Dermatophyte Infections of Skin.
Study would be conducted to compare the efficacy and safety of double than usual dose oral terbinafine versus itraconazole in treatment of dermatophyte infections of skin in patient presenting at dermatology department of Pak…
- Conditions
- Dermatophyte Infection, Terbinafine Adverse Reaction, Itraconazole Adverse Reaction
- Trial name
- NCT04880980
- Testing
- Terbinafine Pill, Itraconazole capsule
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pak Emirates Military Hospital
Supracondylar Fractures, Fracture Fixation
Animated Video and Associated Pain and Anxiety Reduction, Following Pin Removal Post-supracondylar Fracture Fixation
Assessing the reduction in pain and anxiety by the use of showing an animated video of the procedure, among pediatric patients undergoing pin removal after fixation of supracondylar fractures.
- Conditions
- Supracondylar Fractures, Fracture Fixation, Pain Severity, Anxiety
- Trial name
- NCT07234396
- Testing
- K-wire removal with animated procedure video being shown to the patient during its performance., K-wire removal without animated procedure video being shown to the patient during its performance.
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Liaquat National Hospital & Medical College
Poliomyelitis
Phase III Clinical Trial of Sabin Strain Inactivated Poliovirus Vaccine (Vero Cell)
The study aimed to evaluate the safety and immunogenicity of a Sabin strain-based inactivated polio vaccine in infants aged two months (60~89 days).
- Trial name
- NCT07297186
- Testing
- sIPV, wIPV
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Beijing Minhai Biotechnology Co., Ltd
Myopia
650nm Low-level Red-light for Myopia Control and Prevention in Children
A multicenter randomized controlled trial, evaluating the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children.
- Trial name
- NCT05786586
- Testing
- 650 nm low-level red-light
- Where
- China
- Volunteers
- 572 people
- Sponsor
- Beijing Tongren Hospital
Hand, Foot and Mouth Disease (HFMD)
The Phase IVb of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Children
Enterovirus 71 (EV71), a major pathogen causing hand-foot-and-mouth disease (HFMD) worldwide, is a member of the Human Enterovirus species A, family Picornaviridae.
- Trial name
- NCT03001986
- Testing
- inactivated EV71 vaccine (KMB-17 cells)
- Where
- China
- Volunteers
- 40,724 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Acne Vulgaris
Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgaris
This study is to evaluate the therapeutic equivalence and safety of Taro Product to RLD in the treatment of acne vulgaris.
- Trial name
- NCT04134273
- Testing
- CLPG Topical Gel 1%, Clindamycin
- Where
- United States
- Volunteers
- 1,260 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Autistic Disorder
Safety and Effectiveness of D-Cycloserine in Children With Autism
This study will determine the effectiveness of D-cycloserine in reducing symptoms of autism in autistic children.
- Trial name
- NCT00198120
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Cystic Fibrosis
Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Cystic Fibrosis Patients With P. Aeruginosa
The purpose of this study was to evaluate the safety and efficacy of aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis (CF) and lung infection due to Pseudomonas aeruginosa (PA).
- Trial name
- AIR-CF2 (NCT00104520)
- Testing
- AZLI 75 mg two times a day (BID)/three times a day (TID)
- Where
- 56 sites in United States
- Volunteers
- 211 people
- Sponsor
- Gilead Sciences
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