Clinical trials: CONTROL Condition
Psychotic Disorders
Antipsychotic to Treat Psychosis Syndrome
This study assess the safety and effects of atypical antipsychotics in subjects with psychosis syndrome and psychosis risk syndrome.
- Trial name
- NCT02137616
- Testing
- risperidone, olanzapine, Quetiapine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Central South University
Seasonal Allergic Rhinitis
Efficacy Study for the Symptomatic Treatment of Seasonal Allergic Rhinitis
The objective of the study is to evaluate the efficacy and tolerability of Bilastine 20 mg, compared to Cetirizine and placebo for the treatment of seasonal allergic rhinitis.
- Trial name
- NCT00504933
- Testing
- bilastine, Cetirizine
- Volunteers
- 683 people
- Sponsor
- Faes Farma, S.A.
Self Care
Evaluation of the Eversense Continuous Glucose Monitoring System in Type I Diabetic Youth
The purpose of this clinical investigation is to provide pilot clinical data to direct pivotal study development for the pediatric indication of the Senseonics Continuous Glucose Monitoring System (CGM) measurements when compared…
- Trial name
- FNH (NCT03815552)
- Testing
- Eversense Continuous Glucose Monitoring
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Tonsillitis
Perioperative Tonsillectomy Protocol Development
Pediatric patients who are undergoing a tonsillectomy at the Children's hospital will be randomly assigned to one of three drug groups: 1) acetaminophen (Tylenol) administered pre-operatively and a low dose of anti-inflammatory…
- Trial name
- NCT03323047
- Testing
- Acetaminophen, Low-dose Dexamethasone, High-Dose Dexamethasone
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre
Type 1 Diabetes Mellitus
A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes
The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd also known as retogatein compared to placebo, along with oral Vitamin D supplementation, to preserve endogenous…
- Trial name
- DIAGNODE-3 (NCT05018585)
- Testing
- Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Colecalciferol 2000 IU
- Where
- 60 sites in United States, Czechia and 7 more
- Volunteers
- 321 people
- Sponsor
- Diamyd Medical AB
Dental Caries
Trial of a New NuSmile ZR Esthetic Primary Molar Crown
The hypothesis to be tested is that NuSmile ZR esthetic primary molar crowns perform similarly to an established Stainless Steel primary molar crown (3M ESPE) for restoration of primary molar teeth.
- Trial name
- NCT01919515
- Testing
- ZR Crown, Stainless Steel Crown
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- NuSmile, Ltd.
Developmental Language Disorder
Computer-Assisted Vocabulary Intervention for Spanish-English Bilingual Children With Developmental Language Disorder
This study will examine whether computer-assisted vocabulary instruction in Spanish and English helps young bilingual children with developmental language disorder learn and use vocabulary.
- Trial name
- CABVI (NCT07915115)
- Testing
- Bilingual computer-assisted vocabulary intervention (CABVI), English-only computer-assisted vocabulary intervention (CABVI), Usual English-language school services
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Pain, Needle Stick
Testing the Effectiveness of a Parent and Child Mindfulness-Based Intervention for Child Venipuncture
This study investigates the impact of mindfulness-based intervention for children undergoing a blood-draw and their accompanying parent on (a) child ratings of pain and fear, (b) parent and child ratings of parent distress, and…
- Trial name
- NCT03941717
- Testing
- Mindfulness-Based Condition, Unfocused attention Condition
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Insomnia, Neurodevelopmental Disorders
Improving Sleep of Children With Neurodevelopmental Disorders: Pulsed Current Stimulation Versus Melatonin
This is a prospective, randomised controlled trial that evaluates whether transcranial pulsed current stimulation increased total sleep time in children with neuroevelopmental disorder, compared to Melatonin
- Trial name
- NCT06236191
- Testing
- transcranial pulsed current stimulation, Melatonin
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Generalized Epidermolysis Bullosa Simplex
An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)
The proposed Phase 2/3 trial with double-blind and open-label extension phases is an international, multicenter study designed to assess the efficacy and safety of diacerein 1% ointment in patients with generalized EBS.
- Trial name
- EBShield (NCT06073132)
- Testing
- AC-203, Vehicle
- Where
- 30 sites in United States, Australia and 16 more
- Volunteers
- 80 people
- Sponsor
- TWi Biotechnology, Inc.
Adolescent Obesity, Diet
Chrononutrition and Adolescent Weight Control
Comprehensive lifestyle interventions are recommended for the treatment of adolescent obesity; however, evidence suggests that they are not as effective in teens as they are in children and adults.
- Conditions
- Adolescent Obesity, Diet, Weight Loss, Sleep
- Trial name
- NCT04256863
- Testing
- Breakfast / Lunch, Dinner (DIN)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Spinal Cord Injury
Scheduled Telephone Intervention for Individuals With Spinal Cord Injury and Their Families
The purpose of this study is to evaluate whether scheduled telephone intervention with individuals with spinal cord injury (SCI) and their caregivers in the first year following discharge from acute inpatient rehabilitation will…
- Trial name
- SCILink (NCT00693563)
- Testing
- Scheduled Telephone Intervention
- Where
- 2 sites in United States
- Volunteers
- 168 people
- Sponsor
- Jeanne Hoffman
Dental Caries, Pulpotomy
BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars
The objective of this clinical study was to prospectively compare the clinical and radiographic success rates of BiodentineTM pulpotomies versus formocresol pulpotomies in children vital primary molars.
- Trial name
- NCT03779698
- Testing
- BiodentineTM, Formocresol
- Where
- Saudi Arabia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Obesity, Overweight
PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia
The purpose of this National Cancer Institute (NCI) funded study is to develop and test the acceptability and usability of a web \& text message based weight loss intervention for childhood acute lymphoblastic leukemia (ALL)…
- Conditions
- Obesity, Overweight, Weight Loss, Weight Maintenance
- Trial name
- PACE-CALL (NCT01171599)
- Testing
- Fit4Life
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Amblyopia, Visual Training
A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for Amblyopia
The goal of this clinical trial is to learn if an autostereoscopic 3D amblyopia training system works to improve vision in children and adolescents with amblyopia.
- Conditions
- Amblyopia, Visual Training, Visual Functions, Visual Health
- Trial name
- NCT07709832
- Testing
- Autostereoscopic 3D Training, Conventional Patching
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Children, Preschool, Pain and Anxiety
Storytelling Caterpillar - Pain, Anxiety, and Satisfaction
This randomized controlled trial aims to evaluate the effect of using the "Storytelling Caterpillar" toy on pain, anxiety, and parental satisfaction during blood draw procedures in children aged 3 to 6 years.
- Trial name
- SC-PAS (NCT07127432)
- Testing
- The Storytelling Caterpillar
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Koç University
Post-Measles Pneumonia, Measles
Prophylactic Antibiotics in Measles
Objective It is the objective to test whether the use of prophylactic antibiotics in measles infection will reduce the incidence of post-measles pneumonia and/or admissions to hospital with 50%.
- Trial name
- NCT00168532
- Testing
- Sulfamethoxazole-Trimethoprim
- Where
- Guinea-Bissau
- Volunteers
- 218 people
- Sponsor
- Bandim Health Project
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Respiratory Viral Infections, Respiratory Syncytial Virus Infections
Safety and Tolerability Study to Evaluate MEDI-534 in Children 6 to < 24 Months of Age
The overall objective of the MEDI-534 clinical development program is to evaluate the safety, efficacy and tolerability of MEDI-534 for the prevention of serious RSV and PIV3 disease in young infants.
- Conditions
- Respiratory Viral Infections, Respiratory Syncytial Virus Infections, Parainfluenza Virus 3, Human
- Trial name
- CP149 (NCT00493285)
- Testing
- MEDI-534
- Where
- 30 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Infection
Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery
There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection.
- Trial name
- NCT03844776
- Testing
- Co-Amoxiclav, Paracetamol, Chlorhexidine mouthwash
- Where
- Saudi Arabia
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Taibah University
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