Clinical trials: COPD Acute Exacerbation
COPD Exacerbation Acute, COPD Exacerbation
PSV Versus ASV With Intellisync Mode for Delivery of NIV in AECOPD
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined acute worsening of respiratory symptoms requiring additional therapy.
- Trial name
- PAINT-COPD (NCT06160687)
- Testing
- PSV mode during NIV, ASV intellisync
- Where
- India
- Volunteers
- 55 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
COPD, Muscle Weakness
Feasibility of Strength Training in Patients Hospitalized Due to COPD
To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD
- Trial name
- NCT01981200
- Testing
- Resistance training in AECOPD
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Frederikssunds Hospital, Denmark
Angina, Acute Bronchiolitis
Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care
Antimicrobial resistance (AMR), considered one of the greatest global threats by the WHO, justifies the development of initiatives to promote appropriate antibiotic use-especially in primary care, where most antibiotics in France…
- Conditions
- Angina, Acute Bronchiolitis, Acute Bronchitis, COPD Exacerbation (AECOPD)
- Trial name
- GRASP (NCT07359287)
- Testing
- Antibiotic prescribing according to guidelines
- Where
- France
- Volunteers
- 4,500 people
- Sponsor
- University Hospital, Caen
Chronic Obstructive Pulmonary Disease
The Doses of Systemic Steroid in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
It is well established that steroid use is a benefit in the treatment of chronic obstructive pulmonary disease (COPD) with acute exacerbation (AE). But it is still debated about the regimen and dosage of steroid use.
- Trial name
- NCT01215825
- Where
- Taiwan
- Volunteers
- 164 people
- Sponsor
- Far Eastern Memorial Hospital
Safety of NHF in Acute Hypercapnic AECOPD
NHF in Acute Hypercapnic Acute Exacerbation of COPD
Patients with AECOPD and NIV failure and in absence will be treated with NHF device. Inclusion criteria are pH < 7,38 and pCO2 > 45 mm Hg. Patients were treated if pH >7,38 or refusal of therapy.
- Trial name
- NCT03523481
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Jens Bräunlich, MD
Chronic Obstructive Pulmonary Disease
The Impact of Early Pulmonary Rehabilitation on Multidimensional Aspect of Dyspnea in COPD Patients After Exacerbation
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are associated with severe dyspnea and exercise intolerance.
- Trial name
- NCT03611127
- Testing
- pulmonary rehabilitation
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
COPD
The Role of Physical Activity for Acute Exacerbations of COPD
The investigators plan to study the association between physical activity, malnutrition and sarcopenia and the occurrence of acute exacerbations of COPD / the evolution of the COPD assessment test (CAT) over 1 year in a…
- Trial name
- NCT03855670
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Cantonal Hospital of St. Gallen
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Airways Disease
Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation
Background: In chronic obstructive pulmonary disease, the prognosis for patients who have survived an episode of acute hypercapnic respiratory failure due to an exacerbation is poor.
- Conditions
- Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Airways Disease, Chronic Hypercapnic Respiratory Failure
- Trial name
- NCT01513655
- Testing
- LTNIV
- Where
- 4 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Chronic Obstructive Pulmonary Disease
Eosinophilic Cationic Protein as a Biomarker in Diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is a type of obstructive lung disease characterized by long-term breathing problems and poor airflow.
- Trial name
- NCT04008017
- Testing
- Eosinophilic Cationic Protein biomarker
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease
Effect of Remote Physiologic Monitoring (RPM) on Outcomes in COPD Patients
This pre/post study was a retrospective analysis of unplanned hospitalization rates in a cohort of COPD subjects started on remote physiologic monitoring (RPM) at a large, outpatient pulmonary practice.
- Trial name
- NCT05518981
- Testing
- Respiratory Remote Patient Monitor (Spire Health Tag)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Spire, Inc.
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Study to Evaluate the Clinical Value and Safety of Xiyanping Injection in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(COPD) Based on Real-world Clinical Data
The primary objective is to evaluate the effect of Xiyanping injection on the treatment course of intravenous antibiotics for acute exacerbation of chronic obstructive pulmonary disease based on real-world clinical data, and to…
- Trial name
- XYP-202401 (NCT06754865)
- Testing
- Xiyanping injection+ antibiotic, Antibiotic
- Volunteers
- 1,140 people
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Effectiveness and Feasibility of Delivering an Education Program to Patients With an Acute Exacerbation of COPD
The purpose of this study is to determine if it is effective and feasible to provide a chronic obstructive pulmonary disease (COPD) education program to patients admitted with an acute exacerbation of COPD.
- Trial name
- NCT02321215
- Testing
- Introductory Disease Education
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- West Park Healthcare Centre
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Decision-making and Optimization of Ventilatory Support for AECOPD Patients
The goal of this retrospective observational study is to learn about how respiratory support is selected and adjusted in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
- Trial name
- OPTIVENT-COPD (NCT07508943)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sir Run Run Shaw Hospital
COPD - Chronic Obstructive Pulmonary Disease, Muscle Atrophy
Progressive Resistance Training of the Extensor Muscle of the Thigh in COPD-patients Hospitalized With an Exacerbation
We want to test the hypothesis, that resistance training by the use of weigth cuffs on the angle can prevent loss or improve the strength of the quadriceps muscle in COPD patients admitted to hospital due to an exacerbation.
- Trial name
- NCT01812460
- Testing
- Intervention-training-group
- Where
- Denmark
- Sponsor
- Frederikssunds Hospital, Denmark
COPD Exacerbation Acute
Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD
The investigators hypothesized that the empirical use of fluoroquinolones together with beta-lactam antibiotics will change their therapeutic success in patients with acute exacerbations of COPD compared to that in patients in…
- Trial name
- COPD (NCT04879030)
- Testing
- Beta-Lactams, Fluoroquinolone
- Where
- Vietnam
- Volunteers
- 170 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Chronic Obstructive Pulmonary Disease, COPD
Do Blood Tests Help to Decide Which Patients With Flares of Chronic Obstructive Pulmonary Disease (COPD) Need Antibiotics and Steroids?
The goal of this clinical trial is to see if the use of two simple blood tests: C reactive protein and eosinophils, can reduce the use of steroids and antibiotics in patients with flares of chronic obstructive pulmonary disease…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Exacerbation of COPD, AECOPD
- Trial name
- Bidex (NCT06929767)
- Testing
- biomarker-guided decision making, GOLD recommendations
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Obstr Lung Disease
Serum Interleukin 6 in Chronic Obstructive Pulmonary Disease
The aim of this study is to estimate level of IL 6 in COPD patients and its relation to COPD severity and acute exacerbation.
- Trial name
- NCT05214508
- Testing
- interleukin 6
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The Severity Assessment Model for AECOPD With Combination of Disease and Syndrome
The establishment of the AECOPD severity assessment model can quickly and accurately evaluate the condition, which is of great significance for standardizing diagnosis and treatment, improving efficacy, and improving prognosis.
- Trial name
- NCT06918353
- Testing
- Diagnosis and Severity Grading of AECOPD Disease
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Acute Exacerbation of COPD
Non Invasive Ventilation With NAVA vs ASV for AECOPD
Non invasive ventilation is the standard of care in managing patients with exacerbation of chronic obstructive pulmonary disease.
- Trial name
- NCT04414891
- Testing
- Non invasive ventilation
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh