Clinical trials: Caffeine-Related Disorders
Dyskinesias
Pilot Study on Caffeine Efficiency in ADCY5-related Dyskinesia
Heterozygous mutations in the ADCY5 gene cause involuntary early-onset hyperkinetic movements. In addition, patients may have associated psychiatric disorders.There is currently no treatment.
- Trial name
- CAF-ADCY5 (NCT04351360)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Bronchopulmonary Dysplasia
Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia
The aim of this study is to evaluate the effectiveness of caffeine versus probiotics supplementation as adjuvant therapy for preterm neonates with Bronchopulmonary dysplasia (BPD).
- Trial name
- NCT05682807
- Testing
- Caffeine, Probiotic Formula
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Caffeine, Apnea of Prematurity
Caffeine for Preterm Infants With Apnea of Prematurity(AOP)
Nowadays,caffein is commonly used for AOP, and it reduces the intubation rate in preterm infants. However, intubation is needed in about 20%-50% of partial neonates.
- Trial name
- NCT03298347
- Testing
- 80mg/kg of caffeine, 20mg/kg of caffeine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Preterm, Apnea of Prematurity
Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes
Caffeine citrate, the first-line agent for apnea of prematurity, enhances diaphragmatic activity. EDI values of neurally adjusted ventilatory assist (NAVA) modes can be used to quantify the diaphragmatic activity triggered by…
- Conditions
- Preterm, Apnea of Prematurity, Caffeine
- Trial name
- NCT05393817
- Testing
- caffeine citrate
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Seoul St. Mary's Hospital
Neonatal Apnea, Infants
Caffeine Optimization for Oxygen Saturation Index in ELBW Infants
The goal of this clinical trial is to determine whether a higher dose of caffeine citrate can improve breathing and reduce health complications in extremely premature infants, specifically those born before 28 weeks of pregnancy…
- Trial name
- COFIE trail (NCT07216365)
- Testing
- Caffeine Citrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Infant,Premature, Caffeine
Baby-CINO: CaffeINe Treatment Optimisation in Premature Infants
This study investigates how brain activity and breathing changes in premature babies when their dose of caffeine treatment is changed or stopped.
- Trial name
- Baby-CINO (NCT06416956)
- Testing
- Caffeine
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity
Early Caffeine in Preterm Neonates
This is a clinical trial which will investigate whether administration of caffeine, a respiratory stimulant, to preterm babies soon after birth can prevent the need for a breathing tube, or intubation.
- Conditions
- BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity, Hemodynamic Instability, Intubation
- Trial name
- NCT03086473
- Testing
- Caffeine Citrate
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Jennifer Shepherd
Hypoxic-Ischemic Encephalopathy
Dose Optimization of Caffeine for HIE
This is a phase Ib, open-label, dose-validating and safety study of caffeine in neonates with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia.
- Trial name
- NCT06448780
- Testing
- Caffeine citrate 20 mg/kg, Caffeine citrate 30 mg/kg
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Overactive Bladder
Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder
The purpose of this study is to assess the effects of caffeine reduction/elimination on urinary symptoms in women with overactive bladders and compare this therapeutic approach to anticholinergic therapy.
- Trial name
- NCT00780832
- Testing
- Dietary Caffeine reduction, Anticholinergic medication
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- IWK Health Centre