Clinical trials: Calcification
The Skeletal Effects of SSRIs
Do Serotonin Reuptake Inhibitors (SSRIs) Affect Bone Mass in Adolescents
Building on findings from animal studies, pediatric clinical trials, epidemiologic research in adults, and on preliminary findings from the investigators' laboratory in children and adolescents, this project aims to investigate…
- Trial name
- SSRI_BMD (NCT02147184)
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Chadi A. Calarge
Calcinosis
Phase II Study of Calcitonin for Tumoral Calcinosis
OBJECTIVES: I. Determine whether intermittent, long-term, subcutaneous administration of calcitonin increases phosphaturia, reduces hyperphosphatemia, and increases intact parathyroid hormone levels in patients with tumoral…
- Trial name
- NCT00004358
- Testing
- calcitonin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Center for Research Resources (NCRR)
Epilepsy
Bone Mineral Density in Pediatric Epilepsy
What are the effects of the currently used AEDs on bone mineralization in children and adolescents between the ages of 8 to 18? This is a pilot observational study using DEXA scans to measure bone mineral density in 100 patients…
- Trial name
- NCT00204815
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Wisconsin, Madison
Dentinal Loss
Guided Endodontics Compared to Conventional Endodontic Treatment in Calcified Lower Incisors
The dental pulp is a vital tissue that can be prone to physiological or pathological changes. Denticles, pulp stones, or other calcifications are frequently observed within "healthy" pulps.
- Trial name
- NCT06484218
- Testing
- conventional endodontic treatment, Guided endodontic treatment
- Where
- Lebanon
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Osteoporosis, Sarcopenia
Effect of Creatine Supplementation and Exercise on Bone Health
Osteoporosis is an important health problem, costing the Canadian health care system over $2 billion per year. Loss of bone mineral and bone fragility is especially prevalent in postmenopausal women.
- Trial name
- NCT02047864
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
This study evaluates the efficacy of rifampin in the treatment of hypercalcemia and/or hypercalciuria in participants with at least one inactivating mutation of the CYP24A1 gene.
- Conditions
- Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease, Hypercalcemia, Idiopathic, of Infancy, Hypercalciuric Hypercalcemia
- Trial name
- RICHH (NCT03301038)
- Testing
- Rifampin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Vitamin D Deficiency
Vitamin D and Its Affect on Growth Rates and Bone Mineral Density Until Age 5
Abstract Background: Vitamin D affects a wide variety of functions in the body including regulation of calcium, phosphorus, and bone metabolism.
- Trial name
- VitD (NCT01419821)
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Dwarfism, Pituitary, Turner Syndrome
Bone Mineral Density (BMD) in Adolescents With Growth Hormone Deficiency (GHD)
This study is a multicenter, open-label, postmarketing surveillance study. The substudy will collect information on BMD in adolescents and young adults with GHD or Turner syndrome who are completing GH treatment for statural…
- Trial name
- NCT00097526
- Volunteers
- 125 people
- Sponsor
- Genentech, Inc.
Dental Caries, Pulp Exposure, Dental
Comparative Clinical and Radiographic Evaluation of Different Pulpotomy Materials in Primary Molars
This randomized clinical trial compared the clinical and radiographic outcomes of ferric sulfate (FS), mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM), and TheraCal PT used for pulpotomy in primary molars.
- Conditions
- Dental Caries, Pulp Exposure, Dental, Primary Teeth, Primary Molar Pulpotomy
- Trial name
- NCT07769697
- Testing
- Pulpotomy, Mineral Trioxide Aggregate (MTA), Calcium-Enriched Mixture (CEM)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Inonu University
Pulpotomy, Deep Caries
Clinical and Radiographic Evaluation of Bioceramic Putty MTA Versus MTA in Pulpotomy of Immature Permanent Molars
The present study aims to evaluate the clinical and radiographic success of bioceramics putty MTA versus MTA in the pulpotomy of immature permanent molars The main question it aims to answer is: Will the biocermaics putty MTA…
- Trial name
- MTA (NCT06219824)
- Testing
- premixed Bio-ceramic MTA, Conventional MTA
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Childhood Obesity
Lifestyle in Pregnancy and Offspring - Comparison Between Children Born to Obese Women and Children Born to Normal Weight Women
Children born to obese women are at risk of increased adiposity and later adverse metabolic outcomes. We have conducted a follow-up study on an existing clinical trial, called the LiP study (Lifestyle in Pregnancy), registration…
- Trial name
- LiPO (NCT01918423)
- Testing
- Lifestyle intervention during pregnancy
- Where
- Denmark
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Clinical Evaluation Including Pain and Swelling
Clinical and Radiographic Evaluation in Pulpotomy of Primary Molars Using Protooth Vs. MTA
The aim of the study is to evaluate the clinical and radiographic success in pulpotomy using novel fast-setting calcium silicate cement (Protooth) versus MTA in exposed primary molars.
- Trial name
- NCT04710160
- Testing
- Novel fast-setting calcium silicate cement (Protooth)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necrosis
Evaluation of Biodentine and Mineral Trioxide Aggregate in Revascularization of Non Vital Immature Anterior Teeth
the object of this study is to evaluate clinically and radiographically the effect of using Biodentine and Mineral Trioxide Aggregate as coronal plug materials in revascularization of non-vital immature teeth
- Trial name
- NCT03589560
- Testing
- Biodentine, Mineral Trioxide Aggregate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inflammatory Bowel Disease
Physical Activity and Bone Mineral Density in Children and Adolescents With Chronic Inflammatory Bowel Disease
This study is an observational study. The purpose of this study is to assess the relationship between bone health and daily physical activity in children and adolescents with inflammatory bowel disease (IBD).
- Trial name
- PHYSICOSMICI (NCT02341742)
- Testing
- multiple examinations
- Where
- 7 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Lille
Pulpotomy Treatment
Comparative Evaluation of Pulpotomized Primary Molars With Mineral Trioxide Aggregate and New Endodonthic Cement
A new Endodontic Cement (NEC) is being compared with mineral trioxide aggregate in pulpotomy of primary molars.
- Trial name
- NCT00802256
- Testing
- pulpotomy
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Spinal Cord Injury
The Effect of FES on Children With Spinal Cord Injury
Regular exercise is strongly recommended to help maintain a healthy lifestyle. Unfortunately, children and young adults with damaged spinal cords may not be able to exercise regularly.
- Trial name
- NCT00291317
- Testing
- RT 300-P FES Cycle
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Specialized Hospital
Vitamin D Deficiency
Treatment of Vitamin D Insufficiency
The purpose of this study is to answer the following questions: Does vitamin D increase calcium absorption, bone mass and muscle mass and function in women past menopause who have mildly low vitamin D levels? Do these benefits…
- Trial name
- NCT00933244
- Testing
- High Dose Vitamin D3, Low Dose Vitamin D3
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus Type 1
The Effect of Supplementation With Two Different Doses of Vitamin D on Bone Mineral Density, Vitamin D Levels and Hand Grip Strength in Children With Diabetes Mellitus Type 1
The aim of the study is to assess the effect of 12 month supplementation with two different doses of vitamin D ( 500 vs 1000) on bone mineral density, serum 25 hydroxyvitamin D levels and hand grip strength in preadolescents with…
- Trial name
- NCT01277913
- Testing
- Vitamin D3
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Primary Hyperoxaluria, Nephrocalcinosis
International Registry for Primary Hyperoxaluria
The purpose of this study is to collect medical information from a large number of patients in many areas of the world with primary hyperoxaluria.
- Conditions
- Primary Hyperoxaluria, Nephrocalcinosis, Kidney Stones
- Trial name
- NCT00875823
- Where
- 4 sites in United States
- Sponsor
- Mayo Clinic
Atrophied Anterior Maxillary Ridges
GBR With Ptfe With Bovine Bone With and Without Autogenous
Ridge Augmentation in Atrophic Anterior Maxillary Ridges with a Titanium Reinforced Polytetraflouroethelene Membrane and Anorganic Bovine Bone-Derived Mineral in intervention group and Anorganic Bovine Bone-Derived Mineralwith…
- Trial name
- NCT03628157
- Testing
- Geistlich Bio-Oss® bovine bone alone
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University