Clinical trials: Calcification
Epilepsy
Bone Mineral Density in Pediatric Epilepsy
What are the effects of the currently used AEDs on bone mineralization in children and adolescents between the ages of 8 to 18? This is a pilot observational study using DEXA scans to measure bone mineral density in 100 patients…
- Trial name
- NCT00204815
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Wisconsin, Madison
Periapical Healing
Evaluation of Pulpotomy Techniques (Formocresol, Ferric Sulphate, Mineral Trioxide Aggregate)
The goal of this interventional study is to evaluate the different materials used for pulpotomy procedures in deciduous molars. this will help us find out which medicament is more effective in releving which medicament is more…
- Trial name
- MTA (NCT07853183)
- Testing
- FORMOCRESOL PULPOTOMY MATERIAL
- Volunteers
- 120 people
- Sponsor
- Foundation University Islamabad
Deep Caries
Comparing Two Indirect Pulp Capping Agents for Permanent Teeth
Aim of the study: To evaluate clinical and radiographic success rates of silver diamine fluoride versus mineral trioxide aggregate as indirect pulp capping agents in deeply carious young first permanent molars.
- Trial name
- NCT05425368
- Testing
- Silver diamine fluoride, Mineral trioxide aggregate
- Volunteers
- 30 people
- Sponsor
- Cairo University
HIV Infection, Bone Mass
The Effect of Vitamin D and Calcium on Bone in Pediatric HIV
We have observed that vitamin D deficiency, as evidenced by low serum 25(OH)D concentrations, is common in children and adolescents with HIV infection.
- Trial name
- NCT00724178
- Testing
- cholecalciferol plus calcium carbonate
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Direct Pulp Capping
Clinical and Radiographic Assessment of Platelet Rich Fibrin and Mineral Trioxide Aggregate as Pulp Capping Biomaterials
eligible carious teeth with exposed pulp by the undergraduate students will be randomly divided into two groups to be treated with direct pulp capping (A), where (A1) represents the comparator group where teeth will be treated…
- Trial name
- NCT04488679
- Testing
- direct pulp capping
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Rahma Ahmed Ibrahem Hafiz
Direct Pulp Capping in Primary Teeth
DPC in Primary Molars.
To evaluate clinical and radiographical outcomes of direct pulp capping using calcium hydroxide (CH), mineral trioxide aggregate (MTA), and premedicated direct pulp capping (PDPC) with formocresol (FC) in primary teeth.
- Trial name
- NCT05222243
- Testing
- Direct pulp capping with calcium hydroxide, Direct pulp capping with MTA, Direct pulp capping with Formocresol
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Hypopituitarism
Arimidex Multicenter Trial in Growth Hormone (GH) Deficient Boys
The purpose of this study is to see if Arimidex, an aromatase inhibitor, can delay epiphyseal fusion and increase predicted adult height in boys who are growth hormone deficient, in puberty, and who are taking growth hormone.
- Trial name
- NCT00133354
- Testing
- Arimidex (Anastrozole), Growth Hormone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Nemours Children's Clinic
Edentulous Jaw
Horizontal Augmentation With Deproteinized Bovine Bone Mineral Alone or in Combination With Particulate Autogenous Bone
Background: Placement of oral implants is frequently compromised due to atrophy of the alveolar process. Lateral ridge augmentation with an autogenous bone block is frequently necessary to increase the width of the alveolar…
- Trial name
- NCT04755166
- Testing
- Lateral ridge augmentation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- NU-Hospital Organization, Sweden
Children Over 3 Undergoing Dialysis With Secondary Hyperparathyroidism
Calcium Isotope Ratios to Assess Calcium Bone Balance in Dialysis Children Receiving Cinacalcet
Managing bone and mineral disorders associated with chronic kidney disease (CKD-MBD) in children is a complex task. Controlling parathyroid hormone (PTH) levels involves adjusting calcium intake, managing hyperphosphatemia…
- Trial name
- Cin-ca (NCT07007338)
- Testing
- Supplementary blood samples and urines samples
- Where
- 7 sites in France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Spinal Muscular Atrophy Type 3
Whole Body Vibration Therapy in Children With Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) are one of the common physical disabilities in childhood. For SMA, progressive muscle weakness and early fatigue hamper the mobility of the sufferers.
- Trial name
- NCT03056144
- Testing
- whole body vibration therapy
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- The Hong Kong Polytechnic University
Osteopenia, Osteoporosis
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation
This is a Phase 2, open-label, randomized, controlled clinical study of pediatric subjects treated with pamidronate with calcium and vitamin D versus calcium and vitamin D alone following hematopoietic cell transplantation (HCT).
- Trial name
- NCT02074631
- Testing
- Pamidronate, Calcium and vitamin D
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Aortic Valve Stenosis
The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis
This study will confirm the procedural safety and performance of the SAPIEN 3 Ultra System in subjects with severe, calcific AS who are at intermediate operative risk for standard aortic valve replacement.
- Trial name
- NCT03471065
- Testing
- SAPIEN 3 Ultra Delivery System with the SAPIEN 3 Ultra THV
- Where
- 6 sites in Canada, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Edwards Lifesciences
Generalized Arterial Calcification of Infancy, Autosomal Recessive Hypophosphatemic Rickets Type2
Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)
Background: Generalized Arterial Calcification of Infancy (GACI) is a very rare disorder. It can be fatal before birth or by age 6 months. Anumber of people with GACI survive into adulthood.
- Trial name
- NCT03478839
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Osteoporosis
Effects of Jumping on Growing Bones
In this study we will investigate the effects of a high-impact exercise program involving jumping on bone mass (the amount of bone) of the hip and backbone in the growing skeleton.
- Trial name
- NCT00000405
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Osteoporosis
Changes in Bone Mineral Density and Fracture Risk in Patients Receiving Androgen Deprivation Therapy for Prostate Cancer
The aim of this study is to determine the long term effects of two types of hormonal treatment for advanced prostate cancer (LHRH agonists and the antiandrogen bicalutamide)on the bone mineral density of patients.
- Trial name
- NCT00536653
- Testing
- Bicalutamide and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate) and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate)
- Where
- United Kingdom
- Volunteers
- 618 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Familial Mediterranean Fever
Evaluation of Bone Metabolism in Children and Adolescents With Familial Mediterranean Fever
Familial Mediterranean Fever is a chronic auto-inflammatory disease. In the context of chronic inflammation, it seems that, among others, it also affects bone density in children.
- Trial name
- FMF (NCT06034795)
- Where
- Greece
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Cystic Fibrosis
Quantitative Computed Tomodensitometry in Patients With Cystic Fibrosis
The purpose of this study is to conduct a comparative study for the study of bone mineralization evaluated with Quantitative computed tomodensitometry (QCT) compared to the reference technique, Dual-emission X-ray absorptiometry…
- Trial name
- TOMODENS (NCT01837589)
- Testing
- QCT, DXA
- Where
- France
- Volunteers
- 131 people
- Sponsor
- Hôpital Necker-Enfants Malades
The Skeletal Effects of SSRIs
Do Serotonin Reuptake Inhibitors (SSRIs) Affect Bone Mass in Adolescents
Building on findings from animal studies, pediatric clinical trials, epidemiologic research in adults, and on preliminary findings from the investigators' laboratory in children and adolescents, this project aims to investigate…
- Trial name
- SSRI_BMD (NCT02147184)
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Chadi A. Calarge
Prostatic Carcinoma
Imaging of High Grade Prostate Cancer
Management of prostatic carcinoma varies according to stage of disease. Trans-rectal ultrasound guided biopsy is known to underestimate the degree of tumor due to undersampling and random non-targeted technique.
- Trial name
- NCT02177526
- Testing
- Imaging
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoporosis
GRACE - Study of AGN1 LOEP in Osteopenic and Osteoporotic Patients
The study is designed as a retrospective, single-center study for subjects previously treated with the AGN1 LOEP Kit. This will be a non-randomized and non-blinded study.
- Trial name
- NCT05966974
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- AgNovos Healthcare, LLC