Clinical trials: Calculi, Urinary
Stone, Kidney, Lithiasis Renal
Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone
Background: Standard-PCNL was considered as the first choice for ≥2 cm renal stones. Miniaturized technique Mini-PCNL has also been implicated in the past two decades.
- Conditions
- Stone, Kidney, Lithiasis Renal, Surgery
- Trial name
- NCT03771365
- Testing
- Standard-PCNL, Mini-PCNL, SMP
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Benign Prostate Hypertrophy(BPH), Renal Calculi
Stone and Laser Therapies Post-Market Study (SALT)
The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g.…
- Conditions
- Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary
- Trial name
- SALT (NCT06982235)
- Testing
- Ureteroscope system, Laser system
- Where
- 5 sites in United States
- Volunteers
- 238 people
- Sponsor
- Boston Scientific Corporation
Renal Calculi
Energy Ramping Versus Fixed Dose ESWL
This clinical trial compares two techniques of extracorporeal shock wave lithotripsy (ESWL) - energy ramping versus fixed dose - in adult patients with renal stones.
- Trial name
- NCT07334236
- Testing
- Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- mohammed Abdelhafez
Stones, Kidney, Ureter Stones
A Comparative Study Between the Usage of Flexible and Navigable Suction Ureteral Access Sheath Versus Traditional Access Sheath in Retrograde Intrarenal Surgeries
A comparative study between the Usage of Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus Traditional Access sheath in RIRS : Randomized controlled trial .
- Trial name
- NCT07076589
- Testing
- FURS
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Yosseif elhousseiny ammar ahmed
Urolithiasis, Kidney Stones
Assessment of Fluoroscopy Times With Surgeon Versus Technologist Control
This is a prospective randomized trial to study the effect of assigning the control of the fluoroscopic x-ray activation to the surgeon as compared to the radiation technologist.
- Trial name
- NCT02224287
- Testing
- Technologist control of fluoroscopy, Surgeon control of fluoroscopy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Children's Hospital
Primary Hyperoxaluria Type 1
A Study of DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)
A phase 1 study of DCR-PH1 in patients with primary hyperoxaluria type 1 (PH1) to determine the safety, tolerability, pharmacokinetic (PK) and pharmacodynamics (PD) effects of DCR-PH1 administered via-intravenous infusion (IV)
- Trial name
- NCT02795325
- Testing
- DCR-PH1
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 41 people
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Nephrolithiasis, Ureterolithiases
Validation of Low Dose CT for Diagnosis of Urolithiasis
The investigators have developed an extremely low dose renal computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of a single view abdominal radiograph.
- Trial name
- NCT03656913
- Testing
- Extremely low dose CT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Renal Failure, Anuria
Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria
To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.
- Conditions
- Acute Renal Failure, Anuria, Obstructive Uropathy, Ureteric Stones
- Trial name
- NCT02139059
- Testing
- initial urinary drainage, direct ureteroscopy
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Urinary Calculi
Computed Tomography Evaluation of Urinary Stones Densities Compared to in Vitro Analysis of Its Chemical Composition
The ability to predict stone composition, which influences patient treatment, depends on the accurate measurement of CT attenuation of stones.
- Trial name
- NCT04110574
- Volunteers
- 100 people
- Sponsor
- Assiut University
Endourology, Stones, Kidney
Flexible URS in Management of Renal Stones in Anomalous Kidney
The urotheliasis is a common problem encountered daily by all urologists worldwide with rates up to 13% in North America, 9% in Europe and 5% in Asia .
- Conditions
- Endourology, Stones, Kidney, Laser, Congenital Disorders
- Trial name
- NCT05299996
- Testing
- flexible ureterorenoscopy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Pediatric Urolithiasis, Kidney Stone
Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm
This randomized controlled trial aims to compare the efficacy and safety of a Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus a standard ureteral access sheath during flexible ureterorenoscopy (FURS) in…
- Conditions
- Pediatric Urolithiasis, Kidney Stone, Nephrolithiasis
- Trial name
- FANS-UAS (NCT07689565)
- Testing
- Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Renal Stone, Retrograde Intrarenal Surgery
Evaluation of Retrograde Intrarenal Surgery Results and Stone-free Rate in Children With Kidney Stones
There is a global increase in the prevalence of urolithiasis in children attributed to lifestyle changes, dietary habits, climate changes, childhood obesity, and the wider availability of ultrasonography.
- Trial name
- NCT06138704
- Testing
- Retrograde Intrarenal Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ankara City Hospital Bilkent
Pediatric ALL, Stone, Urinary
Indications and Outcomes in Kidney-ureteral Pediatric Lithiasis: Experience of Parma
Incidence of paediatric urolithiasis is increasing in Europe and North America. Nowadays the management of stone disease is a common practice in not endemic country.
- Trial name
- NCT04605315
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
The goal of this observational study is to investigate the feasibility of ultrasound-guided percutaneus nephrolithotomy in patients with kidney stones.
- Trial name
- PCNL (NCT06922006)
- Testing
- Percutaneus nephrolithotomy (PCNL)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Kidney Calculi
Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney Stones
High amounts of calcium in the urine (hypercalciuria) can cause development of kidney stones in children. Treatment for these children includes plenty of fluids, a low-salt diet and medications such as potassium citrate.
- Trial name
- NCT00120731
- Testing
- Potassium Citrate, Acetazolamide, Diet low in oxalate and purines
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Urinary Stones
Prevention of Urinary Stones With Hydration
A randomized clinical trial to investigate the impact of increased fluid intake and increased urine output on the recurrence rate of urinary stone disease (USD) in adults and children.
- Trial name
- PUSH (NCT03244189)
- Testing
- Fluid prescription, Financial incentive, Structured Problem Solving
- Where
- 8 sites in United States
- Volunteers
- 1,658 people
- Sponsor
- Duke University
Stone, Kidney, Stone Ureter
Virtual Reality for Pain Control During Extracorporeal Shock Wave Lithotripsy: a Prospective, Comparative, Randomized Study at a Single Institution
The aim of this study is to prospectively analyze patient satisfaction, pain, delivered energy and clinical effectiveness of using VR as a complimentary treatment modality during SWL.
- Trial name
- NCT05183269
- Testing
- Oncomfort virtual reality monitor (Oncomfort SA, Wavre, Belgium)
- Where
- Belgium
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- AZ Sint-Lucas Gent
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Urinary Lithiasis
Stone Disease of the Urinary Tract in Children
The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management.
- Trial name
- Ped-Urolithia (NCT06032364)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Strasbourg, France
Stone Heterogeneity Index, Shock Wave Lithotripsy
Stone Heterogeneity Index and Shock Wave Lithotripsy Outcomes in Pediatrics
To assess the role of SHI in SWL outcomes for upper urinary tract calculi in pediatric population.
- Trial name
- SHI/SWL (NCT07657832)
- Where
- Egypt
- Volunteers
- 286 people
- Sponsor
- Mansoura University