Clinical trials: Cancer Colonic
Colorectal Cancer
Genetic Markers in Patients With Colorectal Cancer
RATIONALE: Determination of genetic markers for colorectal cancer may improve the identification of patients who are at highest risk for relapse.
- Trial name
- NCT00014079
- Testing
- DNA stability analysis, loss of heterozygosity analysis, microsatellite instability analysis
- Where
- 3 sites in United States
- Volunteers
- 675 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Complications of Surgical Procedures, Surgical Site Infection
Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
The purpose of this study is to evaluate the short-term effect of sealant-assisted skin closure in prevention of surgical site infection after laparoscopic surgery.
- Conditions
- Complications of Surgical Procedures, Surgical Site Infection, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT02426762
- Testing
- Laparoscopic surgery, Skin sealant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Breast Cancer, Colon Cancer
Genomic Structural Variation in Cancer Susceptibility
This study will look for new types of gene changes that may be related to cancer in some patients. Some gene changes (mutations) are passed on from parents to offspring (child).
- Conditions
- Breast Cancer, Colon Cancer, Germ Cell Cancer, Neuroblastoma
- Trial name
- NCT00996710
- Where
- United States
- Volunteers
- 1,275 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Incisional Hernia, Incision Infection
Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections
In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate…) provides a remarkable…
- Trial name
- NCT04394988
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Colon Cancer
Evaluation of the Extraction-site, - Midline Incision vs Off-midline Incision-
The purpose of this study is to evaluate the midline extraction incision in patients with colon cancer. A prospective randomized controlled trial is conducted to compare midline extraction incision with off-midline extraction…
- Trial name
- NCT02253303
- Testing
- midline incision or off-midline incision
- Volunteers
- 100 people
- Sponsor
- Hiroki Yamaue
Colorectal Carcinoma
Clinicopathological Value of p16 Expression in Colorectal Carcinoma
Evaluation of the immunohistochemical expression of p16 in colorectal carcinoma and correlate its expression to different clinical and pathological parameters as patients' ages, sexes, tumor location, histopathological phenotype…
- Trial name
- NCT07047482
- Testing
- Immunohistochemical staining
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
FAP-Familial Adenomatous Polyposis
Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version
Colorectal cancer (CRC) is a leading cause for cancer related mortality in the western world with a lifetime risk of 6%. Etiology is complex, while genetic background significantly affects the risk.
- Trial name
- NCT02354560
- Testing
- Erythromycin
- Volunteers
- 15 people
- Sponsor
- michal roll
Colorectal Cancer
The Biomarkers Of RIsk of Colorectal Cancer (BORICC) Follow-Up (BFU) Study
Worldwide, colorectal cancer is the 3rd most common cancer; risk increases with age and is modified by lifestyle factors notably diet, physical activity and obesity.
- Trial name
- BFU (NCT04005742)
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Colorectal Neoplasms, Colorectal Surgery
Attitudes and Technical Maneuvers Regarding Enterostomy Management and Stoma Creation Among Surgeons
This study was aiming to investigate Chinese surgeons' attitudes toward and technical preferences for stoma creation.
- Trial name
- NCT06735729
- Where
- China
- Volunteers
- 401 people
- Sponsor
- Peking University Cancer Hospital & Institute
Metastatic Colorectal Cancer, Recurrent Colorectal Cancer
Phase I/II Trial of Antagonism of HER in GI Cancer
Recruitment to phase I of the PANTHER trial is complete. Phase II, is to evaluate the best overall response rate for AZD8931 + FOLFIRI treatment.
- Trial name
- PANTHER (NCT01862003)
- Testing
- AZD8931, Irinotecan, Folinic Acid
- Where
- 4 sites in United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
Rectal Neoplasms, Colitis, Ischemic
Anterior Perineal Plane for Ultra Low Anterior Resection of the Rectum
Anal sphincter preserving operations are now commonplace for both cancer and non-cancerous rectal diseases. However, this has not always been the case and this development has been facilitated by the invention of circular…
- Conditions
- Rectal Neoplasms, Colitis, Ischemic, Colitis, Ulcerative
- Trial name
- APPEAR (NCT00534131)
- Testing
- Standard abdominal approach for rectal excision, APPEAR Procedure, Proctectomy
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Queen Mary University of London
Colon Cancer
Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.
The study aims to study the adequacy of bowel preparation (colon cleansing) for afternoon colonoscopies. The conventional regimen of giving bowel prep on the evening prior to the day of the colonoscopy will be compared with that…
- Trial name
- CCF (NCT00687830)
- Testing
- Polyethylene Glycol afternoon, Polyethylene Glycol morning
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Cleveland Clinic Florida
Colon Cancer Stage I, Colon Cancer Stage II
Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt
The investigators will assess and compare Surgical, pathological and oncological outcomes between two laparoscopic procedures conventional colectomy versus complete mesocolic excision for operable colon cancer cases in Upper Egypt
- Trial name
- NCT05421702
- Testing
- laparoscopic conventional colectomy, laparoscopic complete mesocolic excision
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Rectal Cancer, Pelvic Cancer
Advanced Pelvic Surgical Oncology Database - Prospective Observational Study
Retrospective and prospective observational study of patients undergoing advanced pelvic oncological resection for maligancy including multi visceral resection, beyond TME resection and sacrectomy/flap reconstruction/urinary…
- Conditions
- Rectal Cancer, Pelvic Cancer, Gynecologic Cancer, Colon Cancer
- Trial name
- NCT05696002
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Glasgow Royal Infirmary
Cancer, Metastatic, Cancer
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and…
- Conditions
- Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
- Trial name
- NCT03452774
- Testing
- Clinical Trial Matching
- Where
- 68 sites in United States, Puerto Rico
- Volunteers
- 50,000 people
- Sponsor
- Massive Bio, Inc.
Colorectal Neoplasms
A Korean Post-marketing Surveillance Study on Erbitux® in Patients With Metastatic Colorectal Cancer Refractory to Irinotecan-containing Treatment
After consultation with the Korean Health Authorities, the two Post-Authorization Safety Studies EMR 62202-509 (NCT01082315) and EMR 62241-508 (NCT01075828) were combined within one study protocol EMR 062202-551.
- Trial name
- NCT01082315
- Testing
- Erbitux (Cetuximab)
- Where
- South Korea
- Volunteers
- 730 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Colorectal Cancer
Curative Proton Beam Therapy for Patients With Liver Metastasis of Colorectal Cancer
Proton alone therapy is performed -> 5 times a week, 7200 cGy / 15 fractions for 3 weeks total
- Trial name
- NCT03577665
- Testing
- curative proton therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- National Cancer Center, Korea
Colonic Neoplasms
CompariSon Between the EuroPeAn and Japanese pathologiCal InvEstigation for Colon Cancer (SPACE)
In general, the European pathological examination method primarily relies on pathologists and does not require the involvement of surgeons.
- Trial name
- SPACE (NCT06119867)
- Testing
- Japanese pathological investigation, European pathological investigation
- Where
- Russia
- Volunteers
- 430 people
- Sponsor
- Russian Society of Colorectal Surgeons
Malignant Solid Tumors, Primary Brain Tumor
Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research
The investigators will collect biosamples of patient blood and tumour tissue for further immunological analysis of blood cell subpopulations, immunosupressive factors concentration, HLA expression an lymphocytes and tumour…
- Conditions
- Malignant Solid Tumors, Primary Brain Tumor, Melanoma, Soft Tissue Sarcoma
- Trial name
- REGATA (NCT05539677)
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Colorectal Cancer, Gastric Cancer
Familial Colorectal Cancer Registry in Hispanics
Colorectal cancer (CRC) is the second leading cause of cancer in Puerto Rico (PR) accounting for approximately 1,500 individuals annually, which represent 12% of all cancer cases in the island.
- Conditions
- Colorectal Cancer, Gastric Cancer, Colorectal Neoplasms, Colorectal Adenoma
- Trial name
- PURIFICAR (NCT00927680)
- Where
- 2 sites in Puerto Rico
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico