Clinical trials: Cancer Pain
Anxiety, Pain
Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children
Children undergoing leukaemia treatment are exposed to a wide range of chemotherapeutic agents and immunosuppressive therapies during treatment and are therefore at great risk for complications.
- Conditions
- Anxiety, Pain, Fear
- Trial name
- NCT06955338
- Testing
- Music intervention, Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ege University
Acute Pain, Pediatric ALL
VR-PAT and fNIRS to Identify CNS Biomarkers of Pain
This study aims to use functional near-infrared spectroscopy (fNIRS) to identify and quantify pain biomarkers during burn dressing changes and pain relief induced by virtual reality (VR).
- Conditions
- Acute Pain, Pediatric ALL, Procedural Pain, Burns
- Trial name
- NCT06303687
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Nationwide Children's Hospital
Postoperative Pain
Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery
We hypothesize that pregabalin will decrease postoperative pain, as measured by the surrogate markers postoperative pain rating scores and postoperative opioid consumption while improving the quality of recovery following breast…
- Trial name
- NCT00785382
- Testing
- Pregabalin 150 mg
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Childhood Cancer Survivors
Pain and Sleep Disturbances in Children Living Beyond Cancer: A Case-Control Study
Children living beyond cancer (CBC) represent a unique and growing population of young people in need of long-term clinical support.
- Trial name
- NCT07120646
- Testing
- Questionnaire, actigraphy measurement and sleep diary
- Where
- 2 sites in Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Breast Cancer, Joint Pain
Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease
This phase I trial studies how well curcumin works in reducing joint pain in patients who are breast cancer survivors and have joint disease caused by treatment with aromatase inhibitors.
- Trial name
- NCT03865992
- Testing
- Curcumin, Nanoemulsion, Quality-of-Life Assessment
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- City of Hope Medical Center
Chronic Myeloproliferative Disorders, Kidney Cancer
Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation
RATIONALE: Light-emitting diode (LED) therapy may be able to prevent mucositis of the mouth. PURPOSE: Randomized phase II trial to determine the effectiveness of LED therapy in preventing mucositis of the mouth in children who…
- Conditions
- Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma
- Trial name
- NCT00036712
- Testing
- management of therapy complications, pain therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medical College of Wisconsin
Surgical Pain
Erector Spinae Plane Block Versus Caudal Epidural Analgesia
The goal of this clinical trial is to compare the analgesic effect and safety of erector spinae plane block vs caudal epidural block in paediatric population undergoing lower limb cancer surgery.
- Trial name
- NCT06815094
- Testing
- Regional analgesia either CEA or ESP
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- National Cancer Institute, Egypt
Hematological Malignancies
Impact of Child Positioning on Pain During a Lumbar Puncture
This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children.
- Trial name
- PHIPA-PEPL (NCT02834156)
- Testing
- LP in a seated position then LP in a lying position, LP in a lying position then LP in a seated position
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain, Postoperative
Chronic Pain Following Thoracic Surgery
Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem.
- Trial name
- PTPS-18 (NCT01144845)
- Testing
- Thoracic surgery
- Where
- Denmark
- Volunteers
- 702 people
- Sponsor
- University of Aarhus
Post Craniotomy Surgery, Cancer
The Management of Postoperative Craniotomy Pain in Pediatric Patients
The purpose of this prospective, clinical observational trial is to assess the incidence of pain (and analgesia), methods of pain assessment (and by whom), prescribed analgesics, methods of analgesic delivery, and patient/parent…
- Conditions
- Post Craniotomy Surgery, Cancer, Epilepsy, Vascular Malformations
- Trial name
- NCT01576601
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Johns Hopkins University
Pain, Mucositis
Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy
Stomatitis/oral mucositis is a common side effect to chemotherapy. Stomatitis is often associated with painful ulcers in the mouth.
- Trial name
- NCT00357942
- Testing
- morphine solution for injection, morphine mouthwash
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Danish University of Pharmaceutical Sciences
Osteoid Osteoma, Benign Bone Tumor
MR-Guided High Intensity Focused Ultrasound for Pain Management Of Osteoid Osteoma & Benign Bone Tumors in Children and Adults
The Philips Sonalleve HIFU system is expected to be efficacious in reducing pain scores in patients with painful osteoid osteoma and other benign bone tumors, and in reducing their pain medication usage.
- Conditions
- Osteoid Osteoma, Benign Bone Tumor, Pain
- Trial name
- NCT02618369
- Testing
- MR-Guided High Intensity Focused Ultrasound
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Pain, Prostate Cancer
Combination Chemotherapy in Treating Pain in Hormone Refractory Metastatic Prostate Cancer
RATIONALE: Some drugs used in chemotherapy can reduce the pain experienced by some people with cancer. Combining more than one drug may be more effective at reducing cancer pain.
- Conditions
- Pain, Prostate Cancer, Quality of Life
- Trial name
- NCT00003232
- Testing
- clodronate disodium, mitoxantrone hydrochloride, prednisone
- Where
- 21 sites in Canada
- Volunteers
- 227 people
- Sponsor
- NCIC Clinical Trials Group
Pediatric Tumor
Use of Virtual Reality in Pain Management in Pediatric Oncology
DOREVI is a monocentric randomized controlled study that will evaluate the efficacy of virtual reality helmets for pain prevention during invasive care on 78 oncologic pediatric patients.
- Trial name
- DOREVI (NCT05592132)
- Testing
- Virtual reality headset
- Where
- Reunion
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Posterior Fossa Tumors
The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa Surgery
This study evaluate the effects of scalp block versus local infiltration on haemodynamic response to head pin replacement and skin incision and postoperative analgesia in posterior fossa surgery
- Trial name
- NCT02852382
- Testing
- Bupivacaine, morphine patient controlled analgesia
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Colorectal Cancer, Fatigue
Patient-Reported Outcomes in Long-Term Survivors of Colon and Rectal Cancers
RATIONALE: Learning about quality of life, symptoms, and health behaviors in colorectal cancer survivors may help to determine the long-term effects of colon and rectal cancer treatments and may help to improve the quality of…
- Conditions
- Colorectal Cancer, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults, Pain
- Trial name
- NCT00410579
- Testing
- Telephone interview
- Where
- 200 sites in United States
- Volunteers
- 744 people
- Sponsor
- NSABP Foundation Inc
Hematologic Malignancy, Hematologic Non Malignancy
Using of Virtual Reality to Relieve Procedural Pain in Pediatric Oncology.
Medical procedures can be a very frightening experience for children. It is known that children who received painful medical procedures can develop a higher sensitivity of pain during their following experiences.
- Conditions
- Hematologic Malignancy, Hematologic Non Malignancy, Solid Tumor, Childhood, Child, Only
- Trial name
- VIRTUOSO (NCT05042479)
- Testing
- Usual distraction and pain prevention techniques., Virtual reality, Choice between usual distraction or virtual reality
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Nantes University Hospital
Leukemia, Aplastic Anemia
Methadone as an Alternative Treatment for Children Underdoing HSCT
Mucositis is a normal side effect of stem cell transplant which happens as a result of chemotherapy being given prior to a new donor cell infusion (bone marrow transplant).
- Conditions
- Leukemia, Aplastic Anemia, Bone Marrow Failure Syndromes, SCID
- Trial name
- MATCH (NCT06940570)
- Testing
- PCA plus methadone (Experimental), PCA Alone (SOC)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Anxiety, Cancer
Using Parental Involvement During Venipuncture to Reduce Venipuncture Pain and Anxiety in Children With Cancer
This study aims to determine whether parental involvement during venipuncture reduces venipuncture pain and anxiety in children with cancer.
- Conditions
- Anxiety, Cancer, Child, Nursing
- Trial name
- NCT05012904
- Testing
- parent involvement application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mehmet Akif Ersoy University
Cancer of Pancreas, Pain
Acupuncture for Pain Control in Patients With Inoperable Pancreatic Cancer
Pancreatic cancer is the sixth most common cause of cancer death in Hong Kong. Patients suffering from pancreatic cancer are associated with a poor prognosis and survival of less than one year is expected in inoperable tumours…
- Trial name
- NCT02333409
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- Chinese University of Hong Kong