Clinical trials: Cancer Prostate
Adenocarcinoma of Prostate
Impact of Local Anesthesia Type on Cancer Detection Rate in Transrectal Ultrasound Guided Prostate Biopsy
Transrectal ultrasound guided prostate biopsy (TRUS-Bx) is the gold standard method for prostat cancer diagnosis. Cancer detection rate is an important issue in TRUS-Bx.
- Trial name
- NCT02025361
- Testing
- intrarectal lidocaine gel, periprostatic nerve blockade
- Where
- Turkey (Türkiye)
- Volunteers
- 422 people
- Sponsor
- Bagcilar Training and Research Hospital
Prostate Cancer, Treatment
Comparison H-FIRE and Laparoscopic RP in Treating Men With Localized Prostate Cancer
This trial is comparing the functional and oncological outcomes in treating men with prostate cancer between high-frequency irreversible electroporation and laparoscopic radical prostatectomy.
- Trial name
- NCT04278261
- Testing
- Focal therapy(high-frequency irreversible electroporation), laparoscopic radical prostatectomy
- Where
- China
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Prostate Biopsy, Antibiotic
Transperineal MRI-TRUS Fusion Guided Prostate Biopsy With vs Without Antibiotic Prophylaxis
Prostate biopsy is indicated in patients with suspected prostate cancer and has been traditionally performed through the rectum using antibiotic prophylaxis.
- Trial name
- NORAPP (NCT04146142)
- Testing
- Transperineal prostate biopsy with or without antibiotic prophylaxis
- Where
- 2 sites in Germany, Norway
- Volunteers
- 550 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Can MRI of the Prostate Combined With a Radiomics Evaluation Determine the Invasive Capacity of a Tumour
Prostate cancer is the most common cancer diagnosed in men in Canada. Magnetic resonance imaging (MRI) may become a valuable tool to non-invasively identify prostate cancer and assess its biological aggressiveness, which in turn…
- Trial name
- MRI-PREDICT (NCT05024162)
- Testing
- MRT Accuracy, MRT Stability
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Nova Scotia Health Authority
Prostate Adenocarcinoma, Stage I Prostate Cancer
High-Dose Brachytherapy in Treating Patients With Prostate Cancer
This trial studies the side effects and how well high-dose brachytherapy works in treating patients with prostate cancer that has not spread to other parts of the body.
- Conditions
- Prostate Adenocarcinoma, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT02346253
- Testing
- Internal Radiation Therapy, Bicalutamide, Leuprolide Acetate
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Stanford University
Prostate Cancer
PR.7 Companion Trial: Effect of Intermittent Versus Continuous Androgen Suppression on Bone Loss and Body Composition
The purpose of this study is to determine, in patients entered on the National Cancer Institute of Canada (NCIC)-PR.7 trial of intermittent versus continuous androgen ablation, whether the rates of osteoporosis, fractures, and…
- Trial name
- NCT00228124
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Ontario Cancer Research Network
Prostatic Neoplasm
A Randomized Phase II Study of Oral Thalidomide in Patients With Hormone-Refractory Prostate Cancer
This is a phase II study designed to evaluate the potential clinical efficacy of thalidomide in patients with hormone-refractory prostate cancer.
- Trial name
- NCT00001446
- Testing
- thalidomide
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- National Cancer Institute (NCI)
Posterior Bladder Wall Reconstruction, Anterior Bladder Wall Reconstruction
A Technique Improves Urinary Continence in Patients Undergoing Laparoscopic Radical Prostatectomy
Laparoscopic radical prostatectomy (LRP) is the main treatment method for early prostate cancer, and postoperative urinary incontinence is one of the main complications after LRP.
- Conditions
- Posterior Bladder Wall Reconstruction, Anterior Bladder Wall Reconstruction, Anterior Bladder Wall Suspension
- Trial name
- NCT06754488
- Testing
- Posterior Reconstruction, anterior suspension
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Suzhou Municipal Hospital
Hepatocyte Nuclear Factor 1-beta
Long Term Follow up of a Cohort of Children With TCF2 Mutation:Evolution of Endocrine and Renal Function
Anomalies of renal development are well know for patients treated for MODY-5 diabetes due to TCF2 mutation.A recent study confirms the existence of pediatric patients having TCF2 mutation but presenting renal anomalies…
- Trial name
- TCF2 (NCT00760331)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Prostate Cancer
The Role of Tomotherapy in Hypofractionated/Dose Escalated Conformal Radiation Treatment for High Risk Prostate Cancer
Helical tomotherapy is being used to treat the prostate gland, local rates of spread and regional lymph nodes whilst sparing gross structures.
- Trial name
- NCT00126802
- Testing
- Tomotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- AHS Cancer Control Alberta
Prostate Cancer
Prevalence of Neglected Side Effects to Radical Prostatectomy
The purpose of this exploratory data collection is to strengthen our knowledge of some of the rarer distresses following surgical removal of the prostate.
- Trial name
- NCT01742962
- Testing
- Radical prostatectomy for prostate cancer
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Copenhagen University Hospital at Herlev
Prostate Cancer
Nutrition and Lifestyle Changes in Patients With Previously Untreated Stage I or Stage II Prostate Cancer
RATIONALE: Learning about changes in DNA over time in patients with prostate cancer undergoing diet and lifestyle changes may help doctors learn about the long-term effects of these changes on disease progression.
- Trial name
- NCT00739791
- Testing
- exercise intervention, gene expression analysis, polymerase chain reaction
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Advanced Prostate Cancer
Therapy Pathways in the Treatment of Hormone Naïve Prostate Cancer Patients With and Without Comorbidities Treated With Degarelix or Luteinizing-Hormone-Releasing-Hormone (LHRH) Agonists.
The purpose of this study is to detect factors influencing decision making for treatment pathways of hormone-naïve prostate cancer patients with and without comorbidities receiving medicinal androgen deprivation therapy…
- Trial name
- ProComD (NCT02234089)
- Testing
- Degarelix, LHRH agonist (Leuprorelinacetat, Goserelinacetat, Buserelinacetat, Triptorelinacetat)
- Where
- Germany
- Volunteers
- 461 people
- Sponsor
- Ferring Pharmaceuticals
Prostate Cancer
Selenium in Preventing Prostate Cancer
RATIONALE: Selenium supplements may stop or delay the development of prostate cancer in patients at high risk of prostate cancer. It is not yet known which dose of selenium may be more effective in preventing prostate cancer.
- Trial name
- NCT00978718
- Testing
- high-selenium baker's yeast, selenium
- Volunteers
- 700 people
- Sponsor
- University of Arizona
Domestic Partnership, Prostate Carcinoma
Exercising Together During Radiation Treatment
This pilot clinical trial studies how well the Exercising Together program works in helping couples cope with radiation treatment for prostate cancer.
- Conditions
- Domestic Partnership, Prostate Carcinoma, Spouse
- Trial name
- NCT03418025
- Testing
- Exercise Intervention, Questionnaire Administration, Survey Administration
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Breast Cancer, Lung Cancer
T-Cell Response in Patients Receiving Trastuzumab and/or Chemotherapy for HER2-Positive Solid Tumors
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors predict how well patients will respond to treatment. It may also help the study of cancer in the future.
- Conditions
- Breast Cancer, Lung Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- NCT00433407
- Testing
- trastuzumab
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Primary Prostatic Lymphoma on a 66 Year-old Male in Mexico.
A 66-year-old male known case of diabetes and hypertension presented to the urology clinic with a 2-month history of lower urinary tract symptoms (LUTS), particularly poor flow, sense of incomplete bladder emptying, dysuria and…
- Trial name
- NCT07134504
- Where
- Mexico
- Volunteers
- 1 people
- Sponsor
- Instituto Mexicano del Seguro Social
Kidney Cancers, Prostate Cancer
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
The COMFORT study will evaluate an artificial intelligence-based platform developed to support the clinical assessment of kidney and prostate cancer.
- Trial name
- COMFORT (NCT07888322)
- Testing
- Medical Reading, AI assisted Medical reading
- Where
- 6 sites in Germany, Greece and 2 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Advanced Prostate Carcinoma
The Wolverhampton Assessment Tool, a Tool for Patient-reported Wellbeing in the Context of Prostate Cancer
This is a study of the Wolverhampton Assessment Tool (WATapp), a five-item questionnaire for patients with advanced or metastatic prostate cancer to say how they feel normally in terms of pain, urinary frequency, eating, and…
- Trial name
- WATapp (NCT04851639)
- Testing
- Wolverhampton Assessment Tool
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Wolverhampton
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital