Clinical trials: Cancer Prostate
Prostate Adenocarcinoma
Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
This is a Phase 2, randomized two-armed, multi-site study of 138 patients with metastatic castrate sensitive prostate adenocarcinoma. Patients will be randomized 1:1 to receive the fasting mimicking diet, or usual diet.
- Trial name
- NCT05832086
- Testing
- Fasting Mimicking Diet (FMD), Standard Anti-Cancer Diet
- Where
- 3 sites in United States
- Volunteers
- 138 people
- Sponsor
- Stephen Freedland
Prostate Cancer, Radiotherapy Side Effect
PROstate CAncer Radiotherapy - Bowel Quality of Life (PROCAR-BQ)
This is a prospective pilot study to evaluate the mean increase of bowel symptoms after pelvic radiotherapy (RT) in prostate cancer (PCa) patient using the validated \& newly translated EORTC-QLQ PRT20 module.
- Conditions
- Prostate Cancer, Radiotherapy Side Effect, Bowel Dysfunction, Quality of Life
- Trial name
- PROCAR-BQ (NCT05880446)
- Testing
- Bowel symptoms & QoL assessment
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Jules Bordet Institute
Prostate Adenocarcinoma, Recurrent Prostate Carcinoma
Gallium Ga 68-labeled PSMA-11 PET/CT in Detecting Recurrent Prostate Cancer in Patients After Initial Therapy
This clinical trial studies how well gallium Ga 68-labeled prostate-specific membrane antigen (PSMA)-11 positron emission tomography (PET)/computed tomography (CT) works in detecting prostate cancer that has come back (recurrent)…
- Trial name
- NCT02940262
- Testing
- Gallium Ga 68 Gozetotide, Laboratory Biomarker Analysis, Positron Emission Tomography
- Where
- United States
- Volunteers
- 1,138 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Depression, Cancer
Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)
The purpose of this study is to develop and test a new intervention to reduce depressive symptoms in post-treatment cancer participants.
- Conditions
- Depression, Cancer, Stage III Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT06811454
- Testing
- MINDSET, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Case Comprehensive Cancer Center
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma
Image-Guided Biopsies in Identifying Mechanisms of Resistance in Participants With Metastatic Castration Resistant Prostate Cancer Undergoing Radioligand Therapy
This trial studies image-guided biopsies work in identifying mechanisms of resistance in participants with castration resistant prostate cancer that has spread to other places in the body and who are undergoing radioligand…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer
- Trial name
- NCT03596710
- Testing
- Image Guided Biopsy
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
A Randomized Trial of External Beam Radiotherapy Versus Cryoablation in Patients With Localized Prostate Cancer
A trial to determine if cryoablation is as effective as radiation in the treatment of men with localized prostate cancer.
- Trial name
- NCT00489060
- Testing
- Cryoablation and External Beam Radiation
- Where
- Canada
- Volunteers
- 244 people
- Sponsor
- University of Calgary
Prostate Cancer
Coping in African American Prostate Cancer Survivors
This study will test the effectiveness of an 8-week group intervention for African American men who have been treated for prostate cancer.
- Trial name
- CAAPS (NCT00589966)
- Testing
- Coping Skills Training, Prostate Cancer Education
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Duke University
Prostate Cancer
Biological Therapy in Treating Patients With Prostate Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop tumor cells from growing. Treating a person's T cells in the laboratory and then reinfusing them may cause a stronger immune response and…
- Trial name
- NCT00039299
- Testing
- therapeutic autologous lymphocytes
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Perillyl Alcohol in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
RATIONALE: Drugs used in chemotherapy use different way to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of perillyl alcohol in treating patients with metastatic…
- Trial name
- NCT00003238
- Testing
- perillyl alcohol
- Where
- 8 sites in United States
- Sponsor
- University of Wisconsin, Madison
Prostate Cancer
The Development and Validation of MRI-AI-based Predictive Models for csPCa
This study retrospectively included patients who underwent prostate magnetic resonance imaging (MRI) and subsequent ultrasound-guided prostate biopsy at Peking University First Hospital from January 2019 to December 2023, and…
- Trial name
- NCT06842264
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Peking University First Hospital
Carcinomas, Amyloidosis
B-Receptor Signaling in Cardiomyopathy
We hope to determine the importance of different genes (including B receptors) in anthracycline-induced cardiomyopathy. This has important benefits to patients exposed to anthracyclines, as this could help determine whether…
- Conditions
- Carcinomas, Amyloidosis, Anal Cancer, Anemia
- Trial name
- NCT01135849
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Daniel Bernstein
Nonmalignant Neoplasm, Prostate Cancer
Pelvic Floor Muscle Training and Biofeedback or Standard Therapy in Men Who Have Undergone Radical Prostatectomy or Transurethral Resection of the Prostate
RATIONALE: Personalized training by a health professional may improve urinary incontinence. It is not yet known whether pelvic floor muscle training and biofeedback are more effective than standard therapy in improving urinary…
- Conditions
- Nonmalignant Neoplasm, Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction
- Trial name
- NCT00632138
- Testing
- exercise intervention, questionnaire administration, biofeedback
- Where
- 37 sites in United Kingdom
- Volunteers
- 800 people
- Sponsor
- Aberdeen Royal Infirmary
Prostate Cancer
Modified Radical Prostatectomy for Prostate Cancer Patients With Enlarged Prostate and Severe Lower Urinary Tract Symptoms: a Single-center, Retrospective Study
The goal of this retrospective, observational study is to preliminarily learn about the safety and efficacy of two-step radical prostatectomy in the treatment of low- to intermediate-risk prostate cancer patients with enlarged…
- Trial name
- Two-step RP (NCT06347614)
- Testing
- Two-step Radical Prostatectomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Prostate Cancer
A Web-based Peer Navigation Program for Men With Prostate Cancer
One in nine Canadian men will be diagnosed with prostate cancer (PC) in their lifetime. Although all treatment options can be effective in controlling the disease, treatment side effects such as problems with erections and…
- Trial name
- NCT05041504
- Testing
- Peer navigation, Active wait list control
- Where
- 3 sites in Canada
- Volunteers
- 184 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Multi-site Decision Impact Study for Decipher
This prospectively designed retrospective clinical utility study will evaluate urologists' treatment recommendations before and after reviewing Decipher results for selected patient cases.
- Trial name
- ASSESS-D (NCT02034825)
- Testing
- Decipher Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- GenomeDx Biosciences Corp
Prostate Cancer
Heterogeneity of Tertiary Lymphoid Structures Predicts Distinct Malignancy and Immune Microenvironment in Prostate Cancer: a Retrospective Cohort Study
The aim of this study was to reveal the predictive value of spatial heterogeneity and maturity difference of tertiary lymphoid structure in pathological sections of prostate cancer patients for clinical features and prognosis.
- Trial name
- NCT06484127
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Prostatic Neoplasms, Prostatectomy
Impact of Tamsulosin on Voiding Patterns Following Early Catheter Removal After Robot-assisted Laparoscopic Radical Prostatectomy
To date, there is a lack of consensus concerning the optimal timing for removal of the urethral catheter, its related complications, the effectiveness in prophylactic drug use to reduce complication, and the patient reported…
- Trial name
- NCT01209988
- Testing
- tamsulosin 0.4mg, No medication
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Asan Medical Center
Prostate Carcinoma, Recurrent Prostate Carcinoma
99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
This exploratory study conducted under the RDRC program studies the biodistribution of 99mTc-PSMA-I\&S in patients with prostate cancer who undergo pelvic lymph node dissection.
- Trial name
- NCT04857502
- Testing
- 99mTc-based PSMA Imaging and Surgery Agent, Computed Tomography, Single Photon Emission Computed Tomography
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Intensity Modulated Versus Interstitial - Radiation Therapy
Purpose: The purpose of this trial is to compare two different treatment options for patients with low risk and low-tier intermediate risk prostate cancer.
- Trial name
- NCT00407875
- Testing
- Intensity Modulated External Beam Radiation Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer, Non Small Cell Lung Cancer
Metronomic Oral Vinorelbine in Patients With Metastatic Tumors
Patients with recurrent or metastatic solid tumors receive oral vinorelbine at one of three different doses (30 or 40 or 50 mg).
- Conditions
- Breast Cancer, Non Small Cell Lung Cancer, Prostate Cancer
- Trial name
- NCT00278070
- Testing
- vinorelbine oral formulation
- Where
- 11 sites in Greece
- Sponsor
- Hellenic Cooperative Oncology Group