Clinical trials: Cancer Screening
Retinoblastoma
Photoscreening for Retinoblastoma
Retinoblastoma is the most common pediatric eye malignancy and manifests between 1 and 5 years of age. The tumor is most often diagnosed by leukocoria ( white reflex in the pupil).
- Trial name
- NCT04344652
- Testing
- Photoscreening -
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Myoma
Vision Screening Study for College Students at Nankai University
The prevalence of myopia among high school students in China is as high as 80%-90%. For college students with longer years of education, the majority of myopia and the factors influencing the prevalence of high myopia should be…
- Trial name
- NCT05925153
- Testing
- No intervention
- Where
- China
- Volunteers
- 8,500 people
- Sponsor
- Tianjin Eye Hospital
Cervical Cancer
A Review of Cervical Cancer Screening Practices in Women Age >65
The goal of this research study is to examine adherence to national guidelines for cervical cancer screening in women age >65. Patient surveys will provide information about women age >65 current cervical screening practices and…
- Trial name
- NCT06431724
- Testing
- Patient Survey, Provider Survey
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sarasota Memorial Health Care System
Pediatric Cancer, Quality of Life
Parent/Child Dyad Approach to Symptom Screening for Children With Cancer
Symptoms are common and often severely bothersome in pediatric patients receiving cancer treatments. In order to measure the extent of bothersome symptoms, the Symptom Screening in Pediatrics Tool (SSPedi) was developed.
- Conditions
- Pediatric Cancer, Quality of Life, Symptom Screening
- Trial name
- NCT05012917
- Testing
- Patient/Proxy-SSPedi, Co-SSPedi
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- The Hospital for Sick Children
Tumor
Clinical Application Value of Deep Learning-Based "Opportunistic Screening" for Malignant Tumors on Routine Non-Contrast Chest-Abdomen-Pelvis CT
This study aims to develop and validate a deep learning-based opportunistic multi-cancer screening system using routine non-contrast chest-abdomen-pelvis CT examinations, including CHANCE-Breast, CHANCE-Liver, CHANCE-Kidney, and…
- Trial name
- NCT07639567
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Lian Yang
Cushings Syndrome
Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
Cortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature.
- Trial name
- NCT02646553
- Testing
- Children refered to the obesity clinic
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Haukeland University Hospital
Data Collection
The Galleri® Community Research Program
GRAIL, the company that developed the Galleri test and is sponsoring this study, would like to learn more from individuals who have received the Galleri multi-cancer early detection test.
- Trial name
- NCT06603259
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- GRAIL, Inc.
Myeloproliferative Neoplasms (MPN), Polycythemia Vera (PV)
Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms
This study involves screening for portal vein thrombosis and portal hypertension in patients with Philadelphia negative myeloproliferative neoplasms (MPNs).
- Conditions
- Myeloproliferative Neoplasms (MPN), Polycythemia Vera (PV), Essential Thrombocythemia (ET), Myelofibrosis (MF)
- Trial name
- NCT01816256
- Testing
- Upper gastrointestinal endoscopy and Doppler ultrasound
- Where
- 2 sites in Canada
- Volunteers
- 102 people
- Sponsor
- University Health Network, Toronto
Brugada Syndrome (BrS), Breast Cancer Females
Analysis of the Presence and Cardiac Functional Effects of Anti-NaV1.5 Autoantibodies in Patients With Metastatic Tumors
The overall aim of this study is to identify and characterize anti-NaV1.5 autoantibodies in patients with metastatic breast and colorectal cancer.
- Conditions
- Brugada Syndrome (BrS), Breast Cancer Females, Colon Cancer, ECG Abnormalities
- Trial name
- NCT07364656
- Testing
- ECG
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- IRCCS Policlinico S. Donato
Li-Fraumeni Syndrome
Screening With Whole Body MRI For Detection Of Primary Tumors In Children And Adults With Li-Fraumeni Syndrome (LFS) And Other Cancer Predisposition Syndromes
This study is evaluating Whole Body MRI as a possible screening tool to diagnose cancer for people with LFS and other inherited cancer predisposition syndromes.
- Trial name
- NCT02950987
- Testing
- Whole Body MRI
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Dana-Farber Cancer Institute
Lung Cancer, Small Cell Lung Cancer
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose lung cancer by comparing with clinical standard method…
- Conditions
- Lung Cancer, Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Squamous Cell Carcinoma
- Trial name
- NCT05337163
- Testing
- Diagnostic Test: Sputum DNA methylation analysis, chest CT or pathological examination
- Where
- China
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Nasopharyngeal Carcinoma
Development and Validation of a Deep Learning System for Nasopharyngeal Carcinoma Using Endoscopic Images
Develop a deep learning algorithm via nasal endoscopic images from eight NPC treatment centerto detect and screen nasopharyngeal carcinoma(NPC).
- Trial name
- NCT05627310
- Testing
- Diagnostic
- Where
- 8 sites in China
- Volunteers
- 50,000 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Paraganglioma, Pheochromocytoma
Hereditary Paraganglioma: Evaluation of Screening Methods to Detect Tumors in SDH Positive Carriers
Hereditary paraganglioma -due to SDH (SDHD, SDHB, SDHC) germline mutations- causes paragangliomas and pheochromocytomas. Presymptomatic genetic testing should be offered to all first-degree relatives if an SDH mutation is…
- Trial name
- NCT00188019
- Testing
- diagnosis methods
- Where
- France
- Volunteers
- 248 people
- Sponsor
- University Hospital, Angers
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
HEPATITIS C (HCV), Hepatitis B Virus (HBV)
Community Screening and Management of Hepatitis B, C and Delta in the Mongolian Population Living in France
In Mongolia, mortality from hepatocellular carcinoma (HCC) is one of the highest in the world. Viral hepatitis is the main cause of HCC: the prevalence of hepatitis B (HBV) estimated at 11% In Mongolia, hepatitis C (HCV) at 8.5%…
- Conditions
- HEPATITIS C (HCV), Hepatitis B Virus (HBV), Hepatitis D, Hepatocellular Carcinoma (HCC)
- Trial name
- Mondelta (NCT07038863)
- Testing
- Community screening for hepatitis B, C and delta in the Mongolian population living in France
- Where
- 11 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Hospices Civils de Lyon
Retinoblastoma
Evaluation of MRI of the Pineal Gland in Retinoblastoma
Rationale: Currently baseline brain MRI (magnetic resonance imaging) with extended follow-up of pineal cysts is systematically performed in all new retinoblastoma (Rb) patients, because children with hereditary retinoblastoma…
- Trial name
- TRbFU (NCT06367569)
- Testing
- Screening for trilateral retinoblastoma with MRI
- Where
- Netherlands
- Volunteers
- 607 people
- Sponsor
- Amsterdam UMC, location VUmc
Chlamydia Trachomatis Infection, Gonorrhea
Check it: A New Approach to Controlling Chlamydia Transmission in Young People
This study, named "Check it," is a bundled program for African American (AA) men ages 15-24 that includes community testing for chlamydia and gonorrhea, expedited treatment for subjects who test positive and their female sexual…
- Trial name
- NCT03098329
- Testing
- Ct/GC screening
- Where
- United States
- Volunteers
- 1,907 people, healthy volunteers welcome
- Sponsor
- Tulane University
Lung Carcinoma
Improving Lung Cancer Screening Adherence by Overcoming Barriers for Vulnerable Populations
This study investigates multi-level barriers to lung cancer screening uptake and adherence to lung cancer screening. Identifying cost- and convenience-related barriers to lung cancer screening may help researchers develop…
- Trial name
- NCT04969341
- Testing
- Survey Administration, Electronic Health Record Review
- Where
- United States
- Volunteers
- 947 people
- Sponsor
- Thomas Jefferson University
Cancer, HIV Infections
The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study
Medical illnesses and treatments can cause distress in patients, and medical professionals are very interested in identifying distress quickly to ensure that a patient can receive appropriate support and treatment.
- Trial name
- NCT00824278
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- National Institute of Mental Health (NIMH)
Von Hippel-Lindau Disease
Screening for Endolymphatic Sac Tumours (ELSTs) in Von Hippel-Lindau (vHL) Patients
The purpose of the study is to investigate how best to screen for Endolymphatic sac tumors (ELSTs) in von Hippel-Lindau (vHL) patients in order to diagnose the ELSTs while they are still small so that hearing loss can be…
- Trial name
- NCT02420067
- Where
- Denmark
- Volunteers
- 380 people
- Sponsor
- Marie Luise Bisgaard, MD