Clinical trials: Cardiac Anaesthesia
Postoperative Confusion, Postoperative Delirium
Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
The goal of this randomized, double blinded study is to examine in children whether postoperative agitation can be reduced. The main question it aims to answer is Will optimized, monitor guided analgesic treatment and…
- Conditions
- Postoperative Confusion, Postoperative Delirium, Postoperative Pain, Acute, Postoperative Complications
- Trial name
- ANNA (NCT05785689)
- Testing
- Dexmedetomidine
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Reference Values
Reference Values for Pulse Induced Continuous Cardiac Output (PiCCO) Variables in Children
Pulse induced continuous cardiac output (PiCCO) is an established technology for measurement of advanced hemodynamic variables in critically ill patients.
- Trial name
- NCT01283529
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Brugada Syndrome (BrS), Ventricular Arrhythmia
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
The goal of this observational study is to evaluate the perioperative risk of malignant ventricular arrhythmias in adult patients diagnosed with Brugada Syndrome undergoing anaesthetic procedures.
- Conditions
- Brugada Syndrome (BrS), Ventricular Arrhythmia, Anesthesia, Sedation
- Trial name
- PROSP_BRUGANAE (NCT07655102)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Clinic of Barcelona
Aortic Stenosis
Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve Replacement
This study proposes to perform a descriptive analysis and pilot observational study looking at the types and quantity of anesthetic agents used and their associations with outcomes among patients scheduled to receive transfemoral…
- Trial name
- NCT02786264
- Testing
- Dexmedetomidine with propofol, Propofol
- Volunteers
- 186 people
- Sponsor
- Yale University
Post Operative Arrythmia, Anesthesia
Corticosteroids Prevent the Atrial Fibrillation After Cardiac Surgery
Cardiopulmonary bypass and cardiac surgery are associated with a significant systemic inflammatory response that has been suggested playing a causative role in the development of postoperative atrial fibrillation (POAF).
- Conditions
- Post Operative Arrythmia, Anesthesia, Cardiac Surgery, Corticosteroids
- Trial name
- NCT06802432
- Testing
- 1 g of methylprednisolone (divided into 250 mg every 6h started once the patient arrived the pos-toparative ICU)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Ain Shams University
Hypercapnia
Trancutaneous Monitoring to Avoid Hypercapnea During Complex Catheter Ablations
Use of trancutaneous CO2 (TC02) monitoring to aide in titration of sedation of midazolam and fentanyl. Trancutaneous readings validated with invasively obtained specimens from existing arterial sheaths required during AF and VT…
- Trial name
- TCO2 (NCT01815034)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Anesthesia Awareness
Heart Rate Variability to Quantify General Anesthesia Depth
The shortage of anesthetic agents can lead to intraoperative awareness while overdosing can trigger severe intra and postoperative problems.
- Trial name
- NCT04788732
- Testing
- ECG and EEG monitoring
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Atrial Septal Defect, Ventricular Septal Defect
Regional Anesthesia Following Pediatric Cardiac Surgery
The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.
- Conditions
- Atrial Septal Defect, Ventricular Septal Defect, Pain, Procedural
- Trial name
- NCT05688670
- Testing
- Regional Anesthesia, Wound infiltration, Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duke University
Anaesthesia, Toxicity
Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
The purpose of this prospective randomised study is to investigate electrocardiographic alterations after intravascular injection of three different test solutions of bupivacaine and epinephrine in anaesthetised children up to 16…
- Trial name
- NCT01091766
- Testing
- intravenous injection of test solution
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Tetralogy of Fallot
Comparison of RVOT Gradient Under Anaesthesia With Post-operative Gradient in Patients Undergoing TOF Repair
The primary objective of the study will be to compare intraoperative post TOF repair RVOT gradient under two different anaesthetic depths.
- Trial name
- NCT03234582
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Professional Burnout, Professional Stress
Impact of a Curriculum About Professionalism on Stress Response During a Critical Situation
The purpose of this study is to evaluate the impact of a curriculum about professionalism on stress response during a critical situation in anesthesiology residents.
- Conditions
- Professional Burnout, Professional Stress, Anesthesia, Medical Education
- Trial name
- NCT04192097
- Testing
- Professionalism curriculum
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Grenoble Alps
Strabismus, Anesthesia, General
The Effect of Anaesthesia Depth on Oculo-cardiac Reflex
This study was designed to determine the effect of the depth of anesthesia on the oculocardiac reflex (OCR) during pediatric strabismus surgery.
- Trial name
- NCT02379546
- Testing
- Desflurane, Bispectral index monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Tokat Gaziosmanpasa University
Emergence Delirium
Dexmedetomidine-Midazolam vs. Ketamine-Midazolam on Emergence Delirium
Fifty children undergoing heart catheterization without local anesthesia in the skin will be randomly divided into two groups. Group DM (Dexmedetomidine + Midazolam) and Group KM (Ketamine + Midazolam)
- Trial name
- NCT07427446
- Testing
- Dexmedetomidine and Midazolam, Ketamine and Midazolam
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Patients Undergoing Surgery for Congenital Heart Disease
Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease
Acute kidney injury (AKI) is a major complication after cardiac surgery and has been reported to be associated with adverse outcome.
- Trial name
- NCT02081235
- Testing
- surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Samsung Medical Center
Respiratory Failure, Cardiac Arrest
'Single Hand Used inTubaTing Laryngoscope Evaluation' Study
This is a study to compare the new ShuttleScope with the standard Macintosh Laryngoscope
- Conditions
- Respiratory Failure, Cardiac Arrest, Difficult Intubation, Anesthesia Intubation Complication
- Trial name
- SHUTTLE (NCT04310384)
- Testing
- ShuttleScope, MacIntosh Laryngoscope
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Atrial Septal Defect (ASD), Dexmedetomidine
Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect
The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters.
- Conditions
- Atrial Septal Defect (ASD), Dexmedetomidine, Delirium - Postoperative, Stress Response
- Trial name
- NCT06631534
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Heart Defects, Congenital, Hypoplastic Left Heart Syndrome
Fluid Balance in Children Undergoing Fontan Surgery
This project will evaluate fluid balance and edema formation in children with congenital heart disease in need of a surgical procedure, The Fontan procedure.
- Trial name
- NCT02306057
- Testing
- Pre BCPC, Pre TCPC, BCPC surgery
- Where
- Norway
- Volunteers
- 39 people
- Sponsor
- Oslo University Hospital
Hypotension (MeSH: D007022)
Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years
Blood pressure is routinely monitored during anesthesia in children, but blood pressure alone may not accurately reflect blood flow to vital organs.
- Trial name
- CARFLOW (NCT07847203)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Fasting Period, Intravascular Volume
The Impact of Preoperative Fasting Period on Cardiac Index Variability After Anesthesia Induction in Pediatric Patients
The minimum period of fasting recommended by the 'American Society of Anesthesiologists' for the preoperative period is 6 hours for solid foods and 2 hours for clear liquids.
- Trial name
- NCT03406481
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Marmara University