Clinical trials: Cardiac Catheterisation
Coronary Heart Disease
China PEACE-Retrospective CathPCI Study
Coronary heart disease (CHD) is one of the leading causes of mortality and morbidity. PCI, as a well-proved and booming measure in CHD management, is invasive and of high cost, however the knowledge about the real-life PCI use in…
- Trial name
- NCT01624896
- Volunteers
- 12,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection
Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery
Randomized controlled trial comparing femoral vs internal jugular insertion site of central venous catheters (CVC) in newborns and infants undergoing cardiac surgery.
- Conditions
- Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection, Heart; Surgery, Heart, Functional Disturbance as Result, Congenital Heart Disease
- Trial name
- PRECiSE (NCT03282292)
- Testing
- Internal jugular vein CVC insertion
- Where
- Italy
- Sponsor
- IRCCS Policlinico S. Donato
Coarctation of the Aorta
Coarctation Of the Aorta Stent Trial
The purpose of this study is to determine whether Cheatham Platinum bare metal stents are safe and effective in the treatment of native and recurrent aortic coarctation in selected children, adolescents and adults.
- Trial name
- COAST (NCT00552812)
- Testing
- Stent therapy of aortic coarctation
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Richard E. Ringel
Anesthesia
The Premedication Properties of Oral Melatonin in Pediatrics Undergoing Therapeutic Cardiac Catheterization
The evaluation of oral melatonin efficacy as premedicant agent in pediatrics undergoing elective cardiac interventions is the primary outcomes of our trail.
- Trial name
- NCT06031961
- Testing
- melatonin
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Shock, Hypotension and Shock
ClearSight Validation in Pediatrics
Specific aim 1: The specific aim of this study is to compare cardiac output measurements as well as cardiac index, and stroke volume obtained via thermodilution during a cardiac catheterization with data obtained by the…
- Trial name
- NCT03701646
- Testing
- Measurement by Clearsight device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction
Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease
This study evaluates whether new flow parameters of the cardiac magnetic resonance imaging (MRI) allow evaluation of parameters for which usually invasive rigth-left heart catheterization are necessary.
- Conditions
- Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction, Fontan Circulation
- Trial name
- NCT07742046
- Testing
- Right-left heart catheterization in magnetic resonance imaging (MRI)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Tobias Rutz
Atherosclerosis, Coronary Artery Disease
XIENCE V® EXCEED: Evaluation of XIENCE V® Catheterization Lab Endpoints and Excellence in Delivery
This trial is to assess physician-determined XIENCE V® EECSS acute performance, deliverability and resource utilization in the catheterization lab during commercial use by various physicians with a range of coronary stenting…
- Trial name
- EXCEED (NCT00731237)
- Where
- 44 sites in United States
- Volunteers
- 2,517 people
- Sponsor
- Abbott Medical Devices
Pulmonary Hypertension, Sickle Cell Anemia
A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study
This study will assess the safety and efficacy of bosentan therapy (in a study known as ASSET) for patients who have high blood pressure in the lungs associated with sickle cell disease.
- Trial name
- ASSET-3 (NCT00360087)
- Testing
- Bosentan
- Volunteers
- 236 people
- Sponsor
- Actelion
Kidney Failure
Angiotensin Converting Enzyme Inhibitors & Contrast Induced Nephropathy in Patients Receiving a Cardiac Catheterization
The purpose of this study is to determine if patients should stop taking their angiotensin converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) around the time of their angiogram in order to prevent contrast…
- Trial name
- NCT00317252
- Testing
- Hold ACEI or ARB
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Hamilton Health Sciences Corporation
Cardiovascular Disease
Study of Non-Invasive Regional Oxygen Saturations in Pediatric Patients Undergoing Cardiac Catheterization
The purpose of this study is to validate the Nonin Near-infrared spectroscopy (NIRS) device to measure regional oxygen saturation in a cohort of children with cardiovascular disease undergoing cardiac catheterization.
- Trial name
- NCT00939224
- Testing
- Model 7600 Regional Oximeter System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Nonin Medical, Inc
Arteriosclerosis
Magnetic Resonance Imaging of Narrowed Arteries
This study will compare four methods of imaging arteries: angiography (x-ray picture) intravascular ultrasound (ultrasound from inside the artery) magnetic resonance imaging (MRI) from outside the body MRI using an antenna to…
- Trial name
- NCT00029575
- Testing
- Surgi-Vision Guidewire Coil
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Disease, Acute Rejection of Cardiac Transplant
Quantitative Detection of Circulating Donor-Specific DNA in Organ Transplant Recipients (DTRT-Multi-Center Study)
The primary goal of this Multicenter Study is to develop and to evaluate a method for measuring donor-specific cell free DNA in blood samples from transplant recipients as markers of rejection.
- Conditions
- Cardiovascular Disease, Acute Rejection of Cardiac Transplant, Cardiac Transplant Rejection, Heart Transplant Failure and Rejection
- Trial name
- DTRT (NCT02109575)
- Testing
- Blood Draw of up to 10 ml
- Where
- 8 sites in United States
- Volunteers
- 540 people
- Sponsor
- Medical College of Wisconsin
Caridovascular Disease, Congenital Heart Disease
Real-time MRI Right Heart Catheterization Using Passive Catheters
Background: Currently, heart catheterization procedures are guided by X-rays. Researchers are developing new techniques to perform heart catheterization without the use of X-rays by investigating possible uses of magnetic…
- Conditions
- Caridovascular Disease, Congenital Heart Disease, Pulmonary Hypertension
- Trial name
- NCT01287026
- Testing
- Cardiac Real-time MRI RHC (Right Heart Catheterization)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiac Catheterization, Electrophysiology Procedure
Post Anesthesia Care Unit (PACU) Weighted Blanket Study
This study is being conducted to evaluate the safety and efficacy of weighted blankets to reduce agitation in patients in the post-procedural phase after cardiac catheterization and electrophysiology procedures in the post…
- Conditions
- Cardiac Catheterization, Electrophysiology Procedure, Pediatric Cardiology
- Trial name
- NCT05632640
- Testing
- Standard of Care, Weighted blanket
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Michigan
Right Ventricular Dysfunction, Cardiopulmonary Diseases
Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0)
RIGHT-NET 2.0 is a multicenter observational study with a retrospective-prospective design that builds on the original RIGHT-NET study.
- Conditions
- Right Ventricular Dysfunction, Cardiopulmonary Diseases, Pulmonary Hypertension
- Trial name
- RIGHT-NET 2 (NCT07851610)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS SYNLAB SDN
Congenital Heart Disease, Pulmonary Arterial Hypertension
4DFlow Magnetic Resonance Imaging in Patients With Pulmonary Hypertension Associated With Congenital Heart Disease
Congenital heart disease is the most common congenital anomaly. The life expectancy of children with congenital heart disease has increased considerably in recent years.
- Trial name
- 4DFlowHTAPCC (NCT03928002)
- Testing
- 4D Flow magnetic resonance imagery, Cardiac catheterization
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Anesthesia
Emergency Surgery Following Pediatric Catheterization
We study the outcome and prequesties of emergency surgeries that were necessary following accidents in the pediatric cardiac catheterization lab
- Trial name
- NCT03244436
- Testing
- Surgery following catheterization
- Volunteers
- 190 people
- Sponsor
- Cairo University
Pulmonary Hypertension, Pulmonary Embolism (Diagnosis)
China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-right Heart Catheterization
Right heart catheterization(RHC) plays a crucial role in the diagnosis and treatment of pulmonary vascular diseases(PVD). In China, the lack of equipment and technical expertise has historically limited the implementation of RHC…
- Conditions
- Pulmonary Hypertension, Pulmonary Embolism (Diagnosis), Pulmonary Arterial Hypertension, Right Heart Catheterization
- Trial name
- CHA-RHC (NCT06954727)
- Testing
- No intervention; Observational study
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- China-Japan Friendship Hospital
Anxiety, Pain
Comfort Talk for Pediatric Cardiac Catheterization
Background: Pre anaesthesia anxiety in children is a strong predictor of postoperative behavior challenges and outcomes. In addition, intra-operative stress can precipitate post-traumatic stress symptomatology.
- Conditions
- Anxiety, Pain, Adaptation, Psychological, Stress, Psychological
- Trial name
- NCT02347748
- Testing
- Reading pre-procedure script, Reading pre-extubation script, Reading 2 scripts
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- The Hospital for Sick Children
Sinus Venosus Defect, Congenital Heart Disease
OPTImal Treatment of Sinus VENOSUS Defect
Sinus venosus defect (SVD) accounts for 10% of atrial septal defects and is characterized by an anomalous pulmonary venous return in the superior vena cava associated with a high situated atrial septal defect.
- Conditions
- Sinus Venosus Defect, Congenital Heart Disease, Sinus Venosus Atrial Septum Defect
- Trial name
- OPTIVENOSUS (NCT05865119)
- Testing
- OPTIMUS covered stent, Surgical correction of a SVD
- Where
- 13 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Chirurgical Marie Lannelongue