Clinical trials: Cardiac Infarct, open to volunteers
Medical Condition Requiring Extracorporeal Organ Support
The University of Freiburg Medical Center Extracorporeal Organ Support Device Registry
A prospective registry collecting pseudonymized clinical and treatment data from all patients treated with extracorporeal organ support (i.e., VV ECMO, VA ECMO, ECPR, Impella, IABP, and others) on the wards of the Department of…
- Trial name
- NCT05811780
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Freiburg
Heart Diseases, ASD - Atrial Septal Defect
Abbott Structural Heart Device Registry
The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.
- Conditions
- Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale
- Trial name
- SH-Registry (NCT06590467)
- Testing
- Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices
- Where
- 36 sites in United States, Denmark and 8 more
- Volunteers
- 2,500 people
- Sponsor
- Abbott Medical Devices
Heart Failure, Cardiogenic Shock
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
There are two primary goals of this multicenter clinical trial that combines an FDA device trial and a phase II drug trial in the same study cohort. These two goals are to: 1.
- Conditions
- Heart Failure, Cardiogenic Shock, Congenital Heart Disease, Cardiomyopathies
- Trial name
- TROLLEY (NCT06080074)
- Testing
- Cardiohelp device (VA-ECMO), Heparin, Bivalirudin
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Cardiogenic Shock
French Observatory on the Management of Cardiogenic Shock 2
The aim of this observational study is to describe the baseline characteristics, management strategies, and early outcomes (during hospitalisation and at 30 days) of patients admitted to intensive care with cardiogenic shock…
- Trial name
- FRENSHOCK 2 (NCT07868757)
- Where
- 2 sites in France
- Volunteers
- 1,000 people
- Sponsor
- French Cardiology Society
Acute Coronary Syndrome
The Harefield Acute Myocardial Infarction Cohort
In this project the investigator's plan to collect blood during a patient's routine angiogram procedure which they will have due to having suffered a heart attack.
- Trial name
- HEART - ACS (NCT04218344)
- Testing
- 60mls of blood donated for research analysis
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Coronary Artery Disease, Ischemic Heart Disease (IHD)
Gangwon PCI Prospective Registry
This prospective, multicenter registry will consecutively enroll patients of all ages undergoing percutaneous coronary intervention (PCI) at four university hospitals in Gangwon Province, Republic of Korea.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease (IHD), Unstable Angina (UA), Non-ST Elevated Myocardial Infarction
- Trial name
- GWPCI (NCT02038127)
- Testing
- Percutaneous Coronary Intervention (PCI)
- Where
- 4 sites in South Korea
- Volunteers
- 10,000 people
- Sponsor
- Yonsei University
STEMI
ReModeling in ST-elevation myocARrdial Infarction: a Comparison of Left VEntricuLar Functions in Long-term Follow-up Among STEMI Patients
Patients diagnosed with STEMI who underwent pPCI were included in this study. The investigators collected comprehensive data on each patient's status, including laboratory findings such as NT-proBNP, troponin levels, and…
- Trial name
- MARVEL (NCT07041840)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Pisa
Myocardial Infarction, Stable Angina
Barts Revascularisation Registry
Despite the year-on-year decrease, coronary artery disease (CAD) still remains one of the leading cause of mortality worldwide. With advances in technology and our understanding of cardiac disease, we can now treat CAD using…
- Trial name
- NCT05255705
- Testing
- Observation only
- Where
- United Kingdom
- Volunteers
- 20,000 people
- Sponsor
- Queen Mary University of London
ST-segment Elevation Myocardial Infarction (STEMI)
Bivalirudin with Prolonged Infusion During PCI Versus Heparin After Fibrinolytic Therapy
This multicenter, randomized controlled trial in China aims to enroll 2,400 patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) within 24 hours post-fibrinolysis.
- Trial name
- BRIGHT-FIT (NCT06861374)
- Testing
- Bivalirudin, Unfractionated heparin
- Volunteers
- 2,400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Inflammation, Cardiovascular Diseases
Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR)
Following acute cardiovascular injury, inflammation is vital to activate reparative mechanisms. However, there is compelling evidence implicating excessive inflammation and dysregulated resolution in fibrosis, ventricular…
- Conditions
- Inflammation, Cardiovascular Diseases, Myocarditis, Pericarditis
- Trial name
- CAIR (NCT06411340)
- Testing
- Observation
- Volunteers
- 1,000 people
- Sponsor
- King's College London
Myocardial Infarction, ST Elevation Myocardial Infarction
Early Discharge Pathway Registry
Despite the year-on-year decrease, coronary artery disease (CAD) still remains one of the leading causes of mortality worldwide.
- Conditions
- Myocardial Infarction, ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction
- Trial name
- NCT06040528
- Where
- 2 sites in United Kingdom
- Volunteers
- 20,000 people
- Sponsor
- Queen Mary University of London
LCx Occlusion STEMI, STEMI
Outcomes of Isolated LCx Occlusion
To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute occlusion.
- Trial name
- NCT06750328
- Volunteers
- 50 people
- Sponsor
- Assiut University
Infarction
Myocardial Infarction Safe Emergency Medicine Accompanying Study: Providing Reperfusion Therapy Within the Recommended Time Limits
The project is a prospective observational study with the aim of system improvement. It represents accompanying research in connection with the implementation of Safe Emergency Medicine , - an initiative under the auspices of the…
- Trial name
- NCT07092904
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University Hospital of North Norway
Acute Myocardial Infarction
Long-term Follow-up Study Following the Approval of Hearticellgram-AMI Administration
This Long-term follow-up is designed to evaluate the safety of patient with Acute Myocardial Infarction who had administered Hearticellgram-AMI.
- Trial name
- NCT07400458
- Testing
- Hearticellgram-AMI
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pharmicell Co., Ltd.
MINOCA, STEMI
Retinal OCTA for Microvascular Dysfunction Evaluation and Outcome Prediction in MINOCA Patients
The aim of this study is to evaluate microvascular dysfunction through OCTA in MINOCA patients. In order to better understand the condition, OCTA will also be performed in two matched patient groups: healthy controls and ACS…
- Conditions
- MINOCA, STEMI, Normal
- Trial name
- REVEAL (NCT07055152)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Young Patients With Acute Myocardial Infarction
Elicit Drugs in Myocardial Infarction
Estimation of prevalence of abuse elicit drugs among young patients admitted with diagnosis of acute myocardial infarction and determination of inhospital out come and cardiovascular complications of those patients
- Trial name
- NCT07919925
- Volunteers
- 100 people
- Sponsor
- Sohag University
Cardiovascular Events, MACE
Tezspire Cardiac Events PASS
The aim of this study is to evaluate the risk of serious adverse cardiovascular events in adolescent and adult patients with severe asthma taking tezepelumab compared to a population receiving standard of care treatment for…
- Trial name
- TRESPASS (NCT06951867)
- Testing
- Tezepelumab
- Where
- 4 sites in United States, Denmark and 2 more
- Volunteers
- 16,640 people
- Sponsor
- AstraZeneca
Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE)
Precision Antithrombotic Therapy
The goal of this observational study is to systematically analyze the relationship between trough/peak concentrations of novel oral anticoagulants (NOACs) and antiplatelet drugs with clinical events, aiming to provide high-level…
- Conditions
- Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE), MI(Myocardial Infarction), Ischemic Stroke
- Trial name
- NCT07654634
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Cardiogenic Shock, Acute Decompensated Heart Failure
Study of Patients Admitted to a Cardiac Intensive Care Unit With Acute CardioVascular Disease
This is a registry of the patients that are admitted to CICU and treated by the Scientific Staff of the 2nd Department of Cardiology, due to an acute cardiovascular disease (acute coronary syndrome, acute heart failure…
- Conditions
- Cardiogenic Shock, Acute Decompensated Heart Failure, Acute Pulmonary Embolism, Acute Myocardial Infarction
- Trial name
- NCT06081205
- Testing
- Admission in the Cardiac Intensive Care Unit (CICU)
- Where
- Greece
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ioannina