Clinical trials: Cardiac Repolarization
Azithromycin Adverse Reaction, Covid19
The Effect of Azithromycin Use on Conduction System of Heart in COVID-19 Positive Children
Azithromycin (AZ) is used in the pediatric group in COVID-19 diseas. It has been reported to cause prolongation in the QT interval in adult age group.
- Conditions
- Azithromycin Adverse Reaction, Covid19, Long QT Syndrome
- Trial name
- NCT04699097
- Testing
- Azithromycin
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Kayseri City Hospital
Chronic Liver Disease (CLD), Liver Cirrhosis
Heart Problems in Children With Chronic Liver Disease
Chronic liver disease (CLD) in children can sometimes lead to complications in other parts of the body, including the heart. The primary purpose of this observational study is to assess the presence and type of cardiac problems…
- Conditions
- Chronic Liver Disease (CLD), Liver Cirrhosis, Cardiac Abnormalities, Portopulmonary Hypertension
- Trial name
- NCT07502196
- Volunteers
- 60 people
- Sponsor
- Assiut University
Ventricular Arrythmia
China Inherited Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry, aiming at building a risk stratification for malignant inherited ventricular arrhythmias, including Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT…
- Trial name
- NCT03880708
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China National Center for Cardiovascular Diseases
Solid Tumors
Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors
Study to assess the potential effects of lurbinectedin (PM01183) at a therapeutic dose on the duration of the QTc interval, measured by electrocardiograms (ECGs), to characterize the PM01183 plasma concentration/QTc relationship…
- Trial name
- NCT02451007
- Testing
- lurbinectedin (PM01183)
- Where
- 16 sites in United States, Spain
- Volunteers
- 39 people
- Sponsor
- PharmaMar
Alternating Hemiplegia of Childhood
HEmiplegia Arrhythmia Retrospective Trial
Alternating Hemiplegia of Childhood (AHC) is a rare and severe disease that is in need of effective, and hopefully even curative, therapies.
- Trial name
- HEART (NCT04944927)
- Testing
- Recording of clinical parameters and electrocardiogram parameters
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Myocardial Repolarization, Healthy
The Effects of Dexmedetomidine on the Heart Beat During Elective Surgery in Children
Dexmedetomidine is a sedative drug that is commonly used to improve calmness and reduce pain in children waking up after surgery.
- Trial name
- DexmedQT (NCT02353169)
- Testing
- Dexmedetomidine, Saline
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Myocardial Repolarization
The Effects of the Anesthetic Drug Propofol on the Way the Heart Recovers Between Beats
We are investigating a new technique for testing the effect of drugs on electrical activity in the heart. Disturbances of this electrical activity can cause life-threatening changes to heart rhythms.
- Trial name
- NCT00358618
- Testing
- Propofol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Brugada Syndrome, Early Repolarization Syndrome
VF Mapping in Brugada and Early Repolarization Syndromes
To determine the values and limitations of ECGI in guiding ablation and risk stratification in patients with BrS and Early Repolarization.
- Trial name
- NCT03764592
- Testing
- radiofrequency ablation
- Where
- 2 sites in Thailand
- Volunteers
- 50 people
- Sponsor
- Pacific Rim Electrophysiology Research Institute
Cardiac Arrest, Long QT Syndrome
Registry of Unexplained Cardiac Arrest
The CASPER will collect systematic clinical assessments of patients and families within the multicenter Canadian Inherited Heart Rhythm Research Network.
- Conditions
- Cardiac Arrest, Long QT Syndrome, Brugada Syndrome, Catecholaminergi Polymorphic Ventricular Tachycardia
- Trial name
- NCT00292032
- Where
- Canada
- Volunteers
- 1,529 people
- Sponsor
- University of British Columbia
Myocardial Repolarization
The Effects of the Anti Nausea Drugs Droperidol and Ondansetron on the Way the Heart Recovers Between Beats
We are investigating a new technique for testing the effect of drugs on electrical activity in the heart. Disturbances of this electrical activity can cause life-threatening changes to heart rhythms.
- Trial name
- NCT00624208
- Testing
- droperidol and saline, ondansetron and saline, droperidol and ondansetron
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Malignant Childhood Neoplasm
Heart Safety Study of Ondansetron in Children Receiving Chemotherapy
We will study the effects of ondansetron on measurements of electrical activity in the heart to make sure doses we are using to prevent nausea and vomiting in children receiving chemotherapy are safe.
- Trial name
- NCT01896440
- Testing
- Ondansetron
- Where
- United States
- Sponsor
- University of Oklahoma
ST Elevation (STEMI) Myocardial Infarction of Other Sites, Repolarization Indices
Relation of Total Ischemic Time to Repolarization Indices and Their Impact on Outcomes Among STEMI Patients Undergoing Primary PCI
1. Evaluate The impact of early versus late presentation on electrocardiographic ventricular repolarization indices. 2. To assess the association between repolarization indices among early, late presentation in relation to…
- Conditions
- ST Elevation (STEMI) Myocardial Infarction of Other Sites, Repolarization Indices, Total Ischemic Time, Primary Percutaneous Coronary Intervention
- Trial name
- NCT07175259
- Testing
- Echocardiography
- Volunteers
- 500 people
- Sponsor
- Assiut University