Clinical trials: Cardiopulmonary Function
Healthy
Quality Control of Cardiopulmonary Exercise Equipment
This study is designed to make sure exercise equipment used by the National Heart, Lung, and Blood Institute is working properly.
- Trial name
- NCT00001883
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pulmonary Disease
Evaluation of the Causes and Disease Processes of Chronic Lung Disease
Chronic lung diseases are disorders associated with abnormalities in any of the structures involved in the process of breathing and bringing oxygen into the lungs and blood.
- Trial name
- NCT00001183
- Where
- United States
- Volunteers
- 6,564 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Respiration Disorders, Body Composition, Beneficial
The Austrian LEAD (Lung hEart sociAl boDy) Study
The LEAD study is the first longitudinal cohort investigating respiratory, cardiac, and metabolic health in a reference population of Austria.
- Conditions
- Respiration Disorders, Body Composition, Beneficial, Metabolic Health
- Trial name
- LEAD (NCT01727518)
- Testing
- As the LEAD study is an observational cohort study, there is no intervention to report.
- Where
- Austria
- Volunteers
- 14,966 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute for Lung Health
Congenital Heart Disease in Children, Infant Development
Evaluations of Cardiopulmonary Function and Motor Development of Congenital Heart Disease
In this single-center, randomized controlled trial, patients (4-8 months) with CHD were randomly assigned to either a recovery group (home-based rehab exercise periodically) supervised by cellphone APP or to a control group.
- Conditions
- Congenital Heart Disease in Children, Infant Development, Infant Conditions, Motor Neuropathy
- Trial name
- NCT05518136
- Testing
- exercise-guidance on rehab APP
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Gejingwa Zhao
Virtual Reality, Congenital Diaphragmatic Hernia
Virtual Reality and Congenital Diaphragmatic Hernia
The study has been designed to investigate the effect of 12 weeks of using virtual reality based exercises on pulmonary functions, exercise capacity, functional performance, and quality of life in children with…
- Conditions
- Virtual Reality, Congenital Diaphragmatic Hernia, Children
- Trial name
- NCT05612503
- Testing
- Traditional physical therapy program, Virtual reality-based exercises
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Qassim University
Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders
Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary Function
To test the hypothesis that leukocyte filtering during cardiopulmonary bypass (CPB) might reduce the inflammatory response and protect the lungs against the acute injury
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders, Complications Due to Coronary Artery Bypass Graft
- Trial name
- PulmFunction (NCT01469676)
- Testing
- Filtering group LG-6, Pall Biomedical Products
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo
ACS (Acute Coronary Syndrome), HF - Heart Failure
A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin
This study investigates the effects of a sequential "lying-sitting-standing" Baduanjin intervention on patients with acute coronary syndrome complicated by heart failure.
- Trial name
- NCT07486791
- Testing
- standard treatment and routine rehabilitation nursing guidance, "Lying-Sitting-Standing" Sequential Baduanjin
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Xiling Qi
Congenital Heart Disease
Fontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term Effects
Cross-sectional study of a national cohort of adolescents with univentricular congenital heart defects and Fontan type palliation.
- Trial name
- NCT02378857
- Where
- Norway
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Muscular Dystrophy, Duchenne
Assessment of Cardiopulmonary Function in Duchenne Muscular Dystrophy
This study seeks to develop and validate non-invasive assessments of cardiac and respiratory muscles with magnetic resonance imaging (MRI) to better predict the natural disease progression of Duchenne muscular dystrophy (DMD) in…
- Trial name
- CPI (NCT02195999)
- Testing
- Magnetic Resonance Imaging (MRI), Pulmonary Function Testing (PFT), Metabolic Exercise Testing using stationary bicycle
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Complex Congenital Heart Disease
Preliminary Efficacy of a Remote Cardiac Rehabilitation Program in Pediatric Patients With Complex Congenital Heart Disease
This study aims to evaluate the preliminary efficacy of a 12-week community-based remote cardiac rehabilitation program on cardiopulmonary function and quality of life in pediatric patients (aged 8 to 18 years) with complex…
- Trial name
- NCT07572435
- Testing
- Community-Based Remote Cardiac Rehabilitation Program, standard of care
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Seoul National University Hospital
Congenital Heart Disease, Cardiopulmonary Bypass
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
The goal of this randomized interventional clinical trial is to learn if a standardized lung volume optimization maneuver (LVOM) is beneficial in 1.
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Cardiac Surgery, Mechanical Ventilation
- Trial name
- ILOCO (NCT07193719)
- Testing
- End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Heart Disease Congenital Complex
Effect of Postop Steroids on Cardiovascular/Respiratory Function in Neonates Undergoing Cardiopulmonary Bypass
This protocol is designed to offer insight into critical illness related corticosteroid insufficiency and steroid supplementation in neonates undergoing cardiac surgery with cardiopulmonary bypass by administering exogenous…
- Trial name
- NCT01595386
- Testing
- Hydrocortisone, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Congenital Heart Disease, Intestinal Disease
Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary Bypass
A randomized, controlled study including infants with non-cyanosis congenital heart disease (CHD) in need of surgical correction involving cardiopulmonary bypass (CPB) was established.
- Conditions
- Congenital Heart Disease, Intestinal Disease, Dysbiosis
- Trial name
- NCT06295575
- Testing
- probiotics containing Bifidobacterium infantis and Lactobacillus
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing Children's Hospital
Pulmonary Fibrosis, COPD
Multiple Breath Washout as a Method for Diagnosing Lung Diseases
Comparison of the new multiple-breath washout method (ndd Medizintechnik Zürich, Trueflow™/Truecheck™) with established methods of lung function diagnostics in patients with idiopathic pulmonary fibrosis, chronic obstructive…
- Conditions
- Pulmonary Fibrosis, COPD, Asthma
- Trial name
- NCT06179342
- Testing
- Multiple-Breath-Washout
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Congenital Heart Defect, Blood Coagulation Disorder
Bedside Evaluation of Coagulation in Children With Congenital Heart Disease
The purpose of this study is to assess coagulation and platelet function in children with congenital heart disease, measured with a bedside device (thromboelastometry and impedance aggregometry).
- Trial name
- POCHEMO (NCT02387944)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Cardiovascular Disease, Renal Insufficiency, Acute
Acetylcysteine Against Acute Renal Insult During Cardiopulmonary Bypass.
The purpose of this study is to determine whether N-acetylcysteine is effective in the prophylaxis of post-cardiopulmonary bypass acute renal impairment.
- Conditions
- Cardiovascular Disease, Renal Insufficiency, Acute, Cardiopulmonary Bypass
- Trial name
- NCT00190034
- Testing
- N-Acetylcysteine 600mg/tab
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Vascular Ring
Functional Capacity and Quality of Life in Patients With Vascular Ring
To investigate the long term functional capacity and quality of life of patients with a history of vascular ring whether they did or did not have corrective surgery.
- Trial name
- NCT04781738
- Testing
- Cardiopulmonary exercise test
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Cardiac Valve Disease
Ultrafiltration on Coagulation Function in Cardiac Surgery
To determine the effect of modified ultrafiltration, which is usually employed for reducing free water at the end of cardiopulmonary bypass (CPB), on coagulation profile in patients undergoing cardiac surgery
- Trial name
- NCT04031144
- Testing
- Ultrafiltration
- Where
- South Korea
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Congenital Heart Disease, Cardiopulmonary Bypass
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair
The aim of this randomized interventional multi-center clinical trial is to determine whether a standardized lung volume optimization maneuver (LVOM), including PEEP titration, improves outcomes in children undergoing…
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Mechanical Ventilation, Peep Titration in Lung Protective Ventilation
- Trial name
- ILOCO-CHD (NCT07486167)
- Testing
- End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Quality of Life, Congenital Heart Disease
Exercise Training in Children With Corrective Cardiac Surgeries
To determine the effects of preoperative exercise therapy on postoperative cardiopulmonary outcomes and quality of life in children with corrective cardiac surgeries.Within literature there is limited evidence on preoperative…
- Conditions
- Quality of Life, Congenital Heart Disease, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT05763238
- Testing
- INTERVENTION GROUP, CONTROL GROUP
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University