Clinical trials: Cardiovascular Condition
Coronary Artery Disease
Postcath Radial Arterial Clamp Time In the CAth Lab
The investigators will assess the effect of different times of radial clamp post procedure on radial artery occlusion and bleeding.
- Trial name
- PRACTICAL (NCT02269722)
- Testing
- Vascular compression device- RADAR TM-Short clamp time, Vascular compression device RADAR TM-Long clamp time
- Where
- Canada
- Volunteers
- 564 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardiovascular Diseases, Heart Diseases
Evans County Studies
To conduct surveillance of cardiovascular morbidity and mortality and its correlation with known risk factors in all cohort study groups in Evans County, Georgia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Angina Pectoris
- Trial name
- NCT00005122
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cardiovascular Diseases, Cerebrovascular Accident
Honolulu Heart Program-Study of Stroke and Dementia
To clarify the relationship of the arterial lesions to aging, define the influence of the arterial changes on the development of stroke, brain infarction, and dementia, and provide a better understanding of vascular dementia.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Cerebrovascular Disorders, Dementia
- Trial name
- NCT00005395
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pediatric Cancers
Carotid Artery Disease in Childhood Cancer Survivors
The goal of this clinical research study is to find out if long-term survivors of childhood head or neck cancer, who received radiation therapy as part of the overall treatment plan, are at increased risk of thickening or…
- Trial name
- NCT00591539
- Testing
- Carotid Ultrasound
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia
Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma
This phase II trial studies giving rituximab before and after a donor peripheral blood stem cell transplant in patients with B-cell lymphoma that does not respond to treatment (refractory) or has come back after a period of…
- Conditions
- B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia, Childhood Burkitt Lymphoma
- Trial name
- NCT00867529
- Testing
- rituximab, peripheral blood stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Fred Hutchinson Cancer Center
Reperfusion Injury, Post Cardiac Arrest Brain Injury
Light Utilization COX-Inhibitory Device Therapy for Infant Cardiac Arrest (LUTICA Study). The LUCID Device is Used in the Treatment of Ischemic Brain Reperfusion Injury Caused by Cardiac Arrest in Pediatric Patients.
Approximately 15,200 children receive cardiopulmonary resuscitation (CPR) for in-hospital cardiac arrest (IHCA) each year in the United States. Of these, about 60% are less than one year of age.
- Trial name
- LUTICA (NCT07556939)
- Testing
- LUTICIA - Light Utilization COX-Inhibitory Device)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mitovation, Inc
Ataxia-Telangiectasia
Study for Treatment of Cancer in Children With Ataxia-telangiectasia
This is a pilot/feasibility study designed to investigate the feasibility of treating children with Ataxia-Telangiectasia (A-T) and cancer with regimens nearly as intense as non-A-T patients with cancer would receive.
- Trial name
- NCT00187057
- Testing
- vinblastine, vincristine, prednisone, daunorubicin, doxorubicin, methotrexate, cyclophosphamide, L-asparaginase, etoposide, cytarabine, mercaptopurine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Jude Children's Research Hospital
Hypoplastic Left Heart Syndrome, Single Ventricle
Transcoronary Infusion of Cardiac Progenitor Cells in Patients With Single Ventricle Physiology
Hypoplastic left heart syndrome (HLHS) and related anomalies involved a single ventricle are characterized by hypoplasia of the left heart and the aorta with compromised systemic cardiac output.
- Conditions
- Hypoplastic Left Heart Syndrome, Single Ventricle, Heart Failure
- Trial name
- TICAP (NCT01273857)
- Testing
- Autologous cardiac progenitor cell transplantation, staged shunt procedure
- Where
- Japan
- Volunteers
- 14 people
- Sponsor
- Okayama University
Heart Diseases, Cardiomyopathy, Congestive
Idiopathic Dilated Cardiomyopathy
To determine the familial occurrence and pathogenesis of idiopathic dilated cardiomyopathy.
- Trial name
- NCT00005201
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Periodontitis, Vascular Disease
Vascular and Periodontal Disease - Microbial, Genetic and Histological Causalities
The purpose of this study is to analyze genetic polymorphisms in genes encoding pro-inflammatory cytokines, and study the genetic predisposition to chronic periodontitis (CP) in combination with atherosclerotic cardiovascular…
- Trial name
- NCT01358630
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Congenital Heart Defects
Outcomes in Patients and Their Closest Relatives Treated for Congenital Heart Disease With Catheter Based or Surgical Techniques
This study compares clinical, self- reported and cost outcomes in children and adolescents treated with pulmonary valve implantation, percutaneous versus open surgical technique.
- Trial name
- MEQC (NCT01421030)
- Testing
- Percutaneous pulmonary valve implantation or open heart surgery
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Coronary Disease, Coronary Artery Disease
XIENCE V® Everolimus Eluting Coronary Stent System India Post-marketing Single-arm Study
XIENCE V® India is a prospective, open-label, multi-center, observational, single-arm study to evaluate XIENCE V® EECSS continued safety and effectiveness during commercial use in real world settings.
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- XIENCE V India (NCT00631228)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent
- Where
- 18 sites in India
- Volunteers
- 1,000 people
- Sponsor
- Abbott Medical Devices
Multiple Myeloma
PAD Combination Therapy Followed by Thal/Dex for Relapsed or Refractory Multiple Myeloma
Prospective multicenter phase 2 study using PAD and Thal/Dex combination sequentially.
- Trial name
- NCT00319865
- Testing
- Velcade, Thalidomide, Adriamycin
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Korean Multiple Myeloma Working Party
Abdominal Aortic Aneurysm, Cardiovascular Events
Tonometry and Duplex Ultrasound to Predict AAA Progression and CV Events in Aneurysm Patients (1-2-3 Trial)
Abdominal aortic aneurysm (AAA) is a common vascular disease and associated with risk of rupture, but also with a high cardiovascular (CV) event rate.
- Trial name
- NCT03989011
- Testing
- Carotid Artery Reactivity test (CAR test), Arterial stiffness
- Where
- 3 sites in Netherlands
- Volunteers
- 167 people
- Sponsor
- Rijnstate Hospital
Coronary Artery Disease, Atheromatosis
Prognostic Indices of Atheromatosis Severity and Coronary Artery Bypass Surgery Outcomes for Patients With Coronary Artery Disease
Coronary artery disease is a multifactorial disease. Traditional risk factors, such as obesity, diabetes, hypertension, stimulate the onset of an inflammatory process in the prone vessel and perivascular adipose tissue, which has…
- Trial name
- NCT06242171
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Onassis Cardiac Surgery Centre
Heart Defects, Congenital, Pediatrics
CHAMP App Cardiac Study and Repository
This is a multi-site research study with an optional research repository that will consist of clinically derived data and photographic or video images of patients in the home setting with complex health conditions to evaluate the…
- Trial name
- CHAMP (NCT06034392)
- Testing
- CHAMP App
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Lori Erickson
Heart Failure
"A Nurse-led Motivational Interviewing Tailored Intervention for Improving Self Care Behaviours and Health Outcomes in Heart Failure Patients in Oman
This is a pilot randomized clinical trial that have employed a motivational interviewing intervention to enhance self-care in heart failure patients.
- Trial name
- MITI (NCT07721909)
- Testing
- Motivational interviewing, Standard Care (Treatment as Usual)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University
Brain Tumor, Vascular Lesion
Factor XIII and Pulmonary Embolism in Neurosurgical Patients
Two studies (Gerlach et al. 2000; Gerlach et al. 2002) described the impact of factor XIII on the risk of prospective hemorrhage for patients undergoing craniotomy.
- Conditions
- Brain Tumor, Vascular Lesion, Factor XIII Deficiency, Pulmonary Embolism
- Trial name
- NCT01106937
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Channelopathies, Brugada Syndrome
Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies
Patients with cardiac channelopathies needing restorative dental treatment will be included in two sessions of the study, using local dental anesthetic: lidocaine 2% with epinephrine and lidocaine 2% without vasoconstrictor.
- Conditions
- Channelopathies, Brugada Syndrome, Long QT Syndrome, Ventricular, Tachycardia
- Trial name
- SLDAPCC (NCT03182777)
- Testing
- Dental restorative procedure
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo General Hospital
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