Clinical trials: Cardiovascular Event
Post-immunisation Apnoea and Bradycardia of Prematurity (AOP)
Predictive Value of Heart Rate Variability on Cardiorespiratory Events
The aim of this study are to investigate whether heart rate variability (HRV) parameters derived from nonlinear time series analysis at five different time points have prognostic utility for assessing the risk of postimmunisation…
- Trial name
- NCT04303494
- Testing
- immunisation
- Where
- Switzerland
- Volunteers
- 292 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Disease, CABG
The 10-Year Extended Follow-up of the DACAB Trial
The goal of this observational study is to learn about the very long-term effects of different antiplatelet strategies in patients who underwent coronary artery bypass grafting (CABG) and participated in the original DACAB trial.
- Conditions
- Coronary Artery Disease, CABG, Antiplatelet Therapy of Coronary Artery Bypass
- Trial name
- DACAB-FE-10Y (NCT07480629)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Renal Injury, Acute
Acute Kidney Injury : Long-term Renal and Cardiovascular Prognosis and Biomarker-based Risk Assessment
Patients who develop severe acute kidney injury (AKI) in intensive care remain at increased long-term risk of mortality, major cardiovascular events, and chronic renal complications, including prolonged dependence on renal…
- Trial name
- AKIRA (NCT07596407)
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atherosclerotic Disease, Carotid
Post-Approval Study of the Guidant Carotid Stent Systems and Embolic Protection Systems: CAPTURE
This purpose of this study is to collect data on the FDA-approved ACCULINK(TM) Carotid Stent System and FDA 510(k)-cleared ACCUNET(TM) Embolic Protection System for the treatment of patients with atherosclerotic disease, when…
- Trial name
- NCT00180492
- Testing
- RX ACCULINK(TM) Carotid Stent System and RX ACCUNET(TM) Embolic Protection System
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Abbott Medical Devices
Acute Coronary Syndrome
A Comparison of the TIMI, GRACE and HEART Scores
Various elements of patient history are checked and entered in the admission Case Recor Form (CRF). Three risk scores are calculated out of these elements, combined with physical examination, laboratory values and ECG-findings.
- Trial name
- HEART (NCT01398631)
- Where
- 10 sites in Netherlands
- Volunteers
- 2,440 people
- Sponsor
- R&D Cardiologie
Hemophilia, Thrombosis
ATHNdataset Registry
The Hemophilia Treatment Center (HTC) where you receive care is working with The American Thrombosis and Hemostasis Network (ATHN) to look at the quality of life of people with blood disorders and problems.
- Conditions
- Hemophilia, Thrombosis, Hemophilia A, Hemophilia B
- Trial name
- NCT06820515
- Where
- United States
- Volunteers
- 200,000 people
- Sponsor
- American Thrombosis and Hemostasis Network
Myocardial Infarction
RElevance of Biomarkers for Future Risk of Thromboembolic Events in UnSelected Post-myocardial Infarction Patients
The study is an open, single center, observational study at the Cardiology Dept at Uppsala University Hospital. The number of patients included will be 410.
- Trial name
- REBUS (NCT01102933)
- Where
- Sweden
- Volunteers
- 425 people
- Sponsor
- Uppsala University
Hypertension
Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County
The Skills-Based Educational strategies for Reduction of Vascular Events in Orange County, CA (SERVE OC) study aims to evaluate the efficacy of a culturally tailored, skills-based, cardiovascular health (CVH) intervention amongst…
- Trial name
- SERVEOC (NCT05641519)
- Testing
- SERVE OC Intervention, Enhanced Standard Intervention
- Where
- United States
- Volunteers
- 483 people
- Sponsor
- University of California, Irvine
Hypertension, Psychosocial Factors
Relationship of Genes and Life Events to Blood Pressure
Research suggests that blood pressure is influenced by both genetic and environmental factors. The goal of this study is to find genes that play a role in blood pressure and understand how they interact with life events (such as…
- Trial name
- NCT00327431
- Testing
- Cheek swab samples for DNA
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Sudden Infant Death Syndrome, Apnea
Incidence and Severity of Cardiorespiratory Events in Infants at Increased Epidemiological Risk for Sudden Infant Death Syndrome (SIDS)
OBJECTIVES: I. Assess and compare the incidence and severity of cardiorespiratory events documented by home monitoring in infants at increased epidemiological risk for sudden infant death syndrome (SIDS). II.
- Trial name
- NCT00004392
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Antithrombin III Deficiency
Safety, Pharmacokinetics and Efficacy of an ATIII Concentrate
To assess the safety, pharmacokinetics and efficacy of a plasma-derived AT-III concentrate in the treatment of subjects with congenital AT-III deficiency.
- Trial name
- NCT00319228
- Testing
- Plasma-derived AT-III concentrate
- Volunteers
- 3 people
- Sponsor
- Instituto Grifols, S.A.
Non-Small Cell Lung Carcinoma, Venous Thromboembolism
Hypercoagulable Parameters as Predictors of Thrombotic Events and Prognosis in Patients With Advanced Non-Small Cell Lung Carcinoma
The association between cancer and thrombosis is well known and the occurrence of thrombotic complications is commonly associated with poor prognosis.
- Trial name
- NCT00192829
- Testing
- Blood sample withdrawal
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Hip Fractures, Perioperative Myocardial Ischemia
Lumbar Plexus Block Upon the Incidence of Ischemic Cardiovascular Events in Elderly Patients With Hip Fracture
The purpose of this study is evaluate the efficacy of perioperative continuous lumbar plexus block in reducing the risk of cardiac ischemic events of elderly patients undergoing surgery for hip fractures, expressed as a reduction…
- Trial name
- NCT01961895
- Testing
- Continuous lumbar plexus (LP) block analgesia, Intravenous patient-controlled analgesia
- Where
- 2 sites in Chile
- Volunteers
- 31 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Systemic Lupus Erythematosus
Clonal Hematopoiesis of Indeterminate Potential and Accelerated Atherosclerosis in Systemic Lupus Erythematosus
Accelerated atherosclerosis in patients with systemic lupus erythematosus (SLE) is not fully explained by Framingham risk factors.
- Trial name
- HEMATOPLUS (NCT05146414)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension, Coronary Artery Disease
Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial
Candesartan is effective in preventing cardiovascular events in patients without restenosis after coronary angioplasty. Therefore, the investigators hypothesized that candesartan after drug-eluting stent (DES) implantation was…
- Trial name
- NCT00139386
- Testing
- Candesartan
- Where
- Japan
- Volunteers
- 1,119 people
- Sponsor
- Kumamoto University
Cardiovascular Event, Coronary Artery Bypass Graft
Glycosylated Hemoglobin and Risk of Perioperative Major Cardiovascular Events in Diabetic Patients Undergoing Coronary Bypass Revascularization (HbA1c)
Glycosylated Hemoglobin (HbA1c) is considered as one of the best markers to assess the glycaemia treatment over a period of 3 to 4 months, and is considered as predictive marker for perioperative mortality and morbidity.
- Conditions
- Cardiovascular Event, Coronary Artery Bypass Graft, Diabetes Mellitus
- Trial name
- NCT03590223
- Testing
- Coronary Bypass Revascularization
- Where
- Switzerland
- Volunteers
- 589 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Diseases, Atherosclerosis
Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD
A growing body of evidence supports associations between cardiovascular health and adverse pregnancy outcome and between adverse pregnancy outcome and atherosclerotic cardiovascular disease and builds on the well-established…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Pregnancy Complications, Adverse Cardiac Event
- Trial name
- CVD_OBS (NCT06406998)
- Testing
- Pre-existing atherosclerotic cardiovascular disease
- Where
- South Korea
- Volunteers
- 5,461,222 people
- Sponsor
- Samsung Medical Center
Hypertension, Cardiovascular Disease
Effects of Angiotensin Converting Enzyme (ACE) Inhibitors Versus Candesartan in Reducing Cardiovascular Events in Primary Treatment of Hypertension
The planned Study will be a retrospective study on the effect of ACE's vs. candesartan on cardiovascular events and on health economic effects in a "real life" setting in Sweden.
- Trial name
- ARBACE (NCT01152567)
- Where
- 56 sites in Sweden
- Volunteers
- 50,000 people
- Sponsor
- AstraZeneca
Coronary Artery Disease
Evaluation Rehabilitation on Glycometabolic State in Non-Diabetic Coronary Artery Disease (CAD) Patients
The purpose of this study is to evaluate the effects of an intensive Cardiac rehabilitation program on glucose metabolism of non-diabetic coronary artery disease patients.
- Trial name
- NCT00917930
- Testing
- physical training
- Sponsor
- IRCCS San Raffaele
Cardiac Arrest, Anxiety Depression
Removing Surrogates Uncertainty to Reduce Fear and Anxiety After Cardiac Events - Kids
This pilot randomized controlled trial (RCT) will test the feasibility and acceptability of the informational intervention program, Heartsight, to reduce caregivers' uncertainty experienced throughout their child's illness…
- Conditions
- Cardiac Arrest, Anxiety Depression, Family Support
- Trial name
- RESURFACE-Kids (NCT07707037)
- Testing
- Education Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Philadelphia