Clinical trials: Cardiovascular Risk Profile
Childhood Obesity, Obesity
Lifestyle Interventions and Metabolic Profile in Obese Children
This study evaluates if promotion of a normocaloric and balanced diet and of physical activity, through an individual- or group-based lifestyle intervention of 12 months, may affect anthropometric measurements and metabolic…
- Conditions
- Childhood Obesity, Obesity, Pediatric Obesity, Dyslipidemias
- Trial name
- NCT03728621
- Testing
- Normocaloric and balanced diet, physical activity
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- University of Milan
Obesity, Surgery
Laparoscopic Sleeve Gastrectomy in Severely Obese Adolescents: Effects on Metabolism
Severe obesity (SO), defined as BMI≥95th percentile, has increased worldwide among adolescents. American studies estimated that 1.3-2.8% of 12-19-year-old individuals have a BMI >40 kg/m2 or a BMI >35 kg/m2 with at least one…
- Trial name
- NCT02594514
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo General Hospital
Carotid Atherosclerosis, Cerebrovascular Accident
Potential Risk Factors for Stroke
Early studies have shown that the immune system may play a role in the development of strokes. Conditions such as high blood pressure, high cholesterol, diabetes, and old age can activate the immune system and increase the risk…
- Conditions
- Carotid Atherosclerosis, Cerebrovascular Accident, Diabetes Mellitus, Hypercholesterolemia
- Trial name
- NCT00001368
- Testing
- cytokine and leukocyte activation profile
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Offspring of Pre-eclamptic Mothers
Cardiovascular Risk in Infants Exposed to Pre-eclampsia in Utero
An increasing number of scientific publications show that high blood pressure is being described in younger and younger children of African ancestry.
- Trial name
- NCT05091827
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Walter Sisulu University
Hypertrophic Cardiomyopathy
CVD Risk Profile in Children With HCM
Hypertrophic cardiomyopathy is a disease of the heart muscle that causes the heart to become thicker and this thickness places children at risk of heart rhythm problems, heart failure and sudden death.To decrease the risk of…
- Trial name
- NCT05510180
- Where
- 10 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Endothelial Function (Reactive Hyperemia)
MOVING - MOtiVation, INtervention and Vascular chanGe
Background: The impact of demographic changes on workplace has increased the importance of effective occupational preventive health programs.
- Trial name
- MOVING (NCT01919632)
- Testing
- health-behavior seminar and endurance exercise
- Where
- 2 sites in Germany
- Volunteers
- 330 people
- Sponsor
- Technical University of Munich
Polycystic Ovary Syndrome
Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS
Cardiovascular risk factors cluster in hyperandrogenic women - including those presenting with the polycystic ovary syndrome - in association with insulin resistance, obesity, and other metabolic disorders.
- Trial name
- NCT00428311
- Testing
- Metformin, Ethynyl-estradiol plus cyproterone acetate
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Ramon y Cajal
Atrial Fibrillation
Hybrid Atrial Fibrillation Ablation Registry
Recently a combined approach of surgeon ablation in combination with endocardial ablation (hybrid ablation) has been introduced.
- Trial name
- NCT02516033
- Volunteers
- 250 people
- Sponsor
- University Medical Center Groningen
Cardiovascular Diseases, Atherosclerosis
Cardiovascular Risk Profile Among Mexican-Americans
To characterize the epidemiology and genetics of apolipoproteins A-I, A-II, B, C-II, C-III, and E in a population of Mexican-Americans in Starr County, Texas.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Heart Diseases
- Trial name
- NCT00005187
- Volunteers
- 2,058 people
- Sponsor
- The University of Texas Health Science Center, Houston
Congenital Hypothyroidism
Influence of Initial Levothyroxine Dose on Neurodevelopmental and Growth Outcomes in Congenital Hypothyroidism
The primary objective of this study is to evaluate the risk-benefit profile of long-term treatment of two different initials treatment schemes with L-T4 on the neurodevelopmental and auxological outcomes in children with…
- Trial name
- NCT05371262
- Testing
- Levothyroxin
- Volunteers
- 72 people
- Sponsor
- Federico II University