Clinical trials: Cataract Surgery
Cataract
Anesthetic and Dilating Gel for Cataract Surgery
To prepare the eye for cataract surgery, drugs must be given to the eye to allow for surgery to take place. Traditionally, dilating drops and drops containing NSAIDs (to control inflammation) are given to the patient well in…
- Trial name
- NCT00335400
- Testing
- Anesthetic Dilating Gel
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Posterior Capsule Opacification, Postoperative Complications
Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
This prospective, randomized, clinical trial looks to compare children undergoing congenital cataract surgery with intraocular lens (IOL) implantation in terms of visual axis obscuration as well as postoperative complications…
- Trial name
- NCT02491918
- Testing
- cataract surgery, Intraocular lens implantation
- Volunteers
- 61 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
Cataract
Total Corneal Astigmatism Prevalence in Cataract Patients
The purpose of this study is to report the prevalence data for total corneal astigmatism (TCA) in cataract surgery candidates.
- Trial name
- NCT06148857
- Testing
- IOLMaster 700
- Where
- China
- Volunteers
- 11,000 people
- Sponsor
- Peking University Third Hospital
Pediatric Cataract, IOL Implantation
Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery
Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the…
- Conditions
- Pediatric Cataract, IOL Implantation, Myopia Progression
- Trial name
- NCT07364370
- Testing
- Atropine Eye drops
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cataract Surgery
The PanOptix Trifocal IOL: A Study of Patient Satisfaction, Visual Disturbances, and Uncorrected Visual Performance
Prospective survey study of patients who previously underwent cataract surgery with the Alcon PanOptix or PanOptix Toric intraocular lens in both eyes.
- Trial name
- NCT04146961
- Testing
- Alcon PanOptix or PanOptix Toric IOL
- Where
- 3 sites in United States
- Volunteers
- 59 people
- Sponsor
- Research Insight LLC
Corneal Disease
Automated Lamellar Keratectomy in Symptomatic Patients With Bullous Keratopathy
To relieve pain in patients with symptomatic bullous keratopathy (BK) until keratoplasty and in patients without visual prediction.
- Trial name
- ALKSBK (NCT00654888)
- Testing
- ALK (automated lamellar keratectomy), Mitomycin
- Volunteers
- 28 people
- Sponsor
- Federal University of São Paulo
Dry Eye
Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery
To evaluate the clinical outcomes of the systemic re-esterified triglyceride (rTG) form of omega-3 fatty acids in patients with dry eye symptoms after cataract surgery
- Trial name
- NCT04411615
- Testing
- Omega 3
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Recruitment of Participants
Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality in Cataract Patients
This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical Cataract diagnosis and treatment.
- Trial name
- NCT04833491
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract, Juvenile
Optic Capture Without Anterior Vitrectomy in Pediatric Cataract Surgery
Purpose: To compare two pediatric cataract surgery procedures: intraocular lens (IOL) optic capture without anterior vitrectomy (AV) and in-the-bag IOL implantation with AV.
- Trial name
- NCT05461040
- Testing
- optic capture, In-the-bag implantation of Intraocular lens
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Ege University
Cataract With Exfoliation Syndrome
Efficacy of a Capsular Tension Ring in Preventing Anterior Capsule Shrinkage After Cataract Surgery in Exfoliation Syndrome
The purpose of this study is to examine the efficacy of a capsular tension ring (CTR) in preventing anterior capsule shrinkage after cataract surgery in exfoliation syndrome (XFS) with no zonular weakness.
- Trial name
- Effect of CTR (NCT01455168)
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- University of Occupational and Environmental Health
Cataract
Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative…
- Trial name
- NCT02581046
- Testing
- Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients, Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Cataract
Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase).
- Trial name
- FEMTOHTO (NCT02835482)
- Testing
- Femtolaser surgery, Phacoemulsification
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Virtual Reality, Eye Disease
Virtual Reality and Its Use in Reducing Perioperative Stress in Cataract Surgery
This project is to evaluate the benefits of utilising virtual reality (VR) headsets with the aim of reducing peri-operative anxiety in cataract surgery and hence reducing the need for sedation in patients with significant stress…
- Conditions
- Virtual Reality, Eye Disease, Cataract Surgery Anesthesia, Cataract Surgery
- Trial name
- NCT06822023
- Testing
- virtual reality mask
- Volunteers
- 75 people
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Cataract, After Cataract
Autonomous Telephone Follow-up After Cataract Surgery
This project will apply AI technology to meet the gap between increasing demand and limited capacity of high- volume healthcare services.
- Trial name
- NCT05213390
- Testing
- Dora
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people
- Sponsor
- University of Plymouth
Cataract, Sleep
The Effect of Cataract Surgery on Sleep Quality
A cataract is a clouding of the crystalline lens inside the eye, which leads to a decrease in vision. It is the most prevalent, treatable cause of visual impairment and blindness in the world.
- Trial name
- NCT02593669
- Testing
- Phacomulsification lens removal cataract surgery with neutral Intraocular lens(IOL) implantation, Phacomulsification lens removal cataract surgery with blue-blocking Intraocular lens(IOL) implantation, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Cataract, Epiretinal Membrane
Combined 25-gauge Vitrectomy and Cataract Surgery With Toric Intraocular Lens With Idiopathic Epiretinal Membrane.
Toric intraocular lens (IOL) is now widely used for the cataract surgery with preoperative corneal astigmatism. Symptomatic epiretinal membrane (ERM) is often treated with 25-gauge transconjunctival sutureless vitrectomy…
- Conditions
- Cataract, Epiretinal Membrane, Corneal Astigmatism
- Trial name
- NCT02328157
- Testing
- Vitrectomy with cataract surgery and toric IOL, Vitrectomy with cataract surgery and common IOL
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Kagawa University
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao