Clinical trials: Celiac Disease
Celiac Disease, Eosinophilic Esophagitis
Prevalence of Eosinophilic Esophagitis in Children With Celiac Disease
Celiac disease (CD) and eosinophilic esophagitis (EE) are distinct diseases of the gastrointestinal tract with specific clinico-pathological characteristics.
- Trial name
- NCT02190513
- Volunteers
- 56 people
- Sponsor
- St. John Health System, Michigan
Celiac Disease in Children, Diabetes Mellitus, Type I
Auto-antibody Dosage From Blood Spots for Diagnosis of Type 1 Diabetes and Celiace Disease
Early diagnosis of type 1 diabetes and celiac disease is very useful, allows early therapy and prevents deaths from the onset of diabetic ketoacidosis.
- Conditions
- Celiac Disease in Children, Diabetes Mellitus, Type I, Screening
- Trial name
- CELDI (NCT06849622)
- Testing
- Test on blood sample, Test on dried blood sample
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Celiac Disease in Children, Gluten Allergy
Mental Perfomance in Patients With Coeliac Disease
Coeliac disease (CD) is an immune-mediated systemic disorder triggered by gluten in genetically predisposed patients. The only available treatment is a strict life long gluten-free diet (GFD), which has been linked to a reduced…
- Trial name
- NCT06519916
- Testing
- Assessment of mental performance
- Where
- Switzerland
- Volunteers
- 444 people
- Sponsor
- University Children's Hospital Basel
Celiac Disease in Children, Eating Behaviors
Eating Behaviors in Children and Adolescents With/Without Celiac Disease
This observational study investigates the prevalence and severity of disordered eating behaviors in adolescents aged 11-17 years with celiac disease.
- Trial name
- NCT07285512
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Celiac Disease in Children
Iron Deficiency and TTG Normalization
The investigators conducted a retrospective, observational cohort study which enrolled CD subjects aged 2-18y, diagnosed between Jan 2016 and Dec 2020.
- Trial name
- NCT05675280
- Testing
- Gluten free diet
- Where
- Israel
- Volunteers
- 118 people
- Sponsor
- Meir Medical Center
Celiac Disease
Can a Very High Result From a Screening Test for Celiac Disease be Used to Diagnose Celiac Disease?
This study is to see if a high response to the TTG screening test for celiac disease is as accurate as the current method of diagnosing celiac disease which entails a general anesthetic and upper endoscopy to obtain biopsies of…
- Trial name
- NCT00175760
- Testing
- Diagnosis of Celiac Disease
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Celiac Disease in Children, Nutrition Disorder, Child
GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)
The investigators propose the Gluten Free Nutrition Optimization through Ultra-processed food Reduction and Improved Strategies for Health (GF-NOURISH) study to demonstrate the feasibility and success of a nutritional education…
- Trial name
- GF-NOURISH (NCT06356220)
- Testing
- Gluten-Free Diet Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Celiac Disease in Children, Autoimmune Diseases
Gluten Reduction and Risk of Celiac Disease
Celiac disease shares many features of other autoimmune diseases such as type 1 diabetes. Recently, it was published that higher amounts of gluten intake increased the risk for celiac disease.
- Conditions
- Celiac Disease in Children, Autoimmune Diseases, type1diabetes
- Trial name
- GRAIN (NCT04593888)
- Testing
- Gluten reduced diet
- Where
- Sweden
- Volunteers
- 1,141 people
- Sponsor
- Lund University
Gastrointestinal Diseases
ESPRESSO (Epidemiology Strengthened by histoPathology Reports in Sweden)
The ESPRESSO study is a collection of data from all computerised gastrointestinal histopathology reports in Sweden. This allows us to study risk factors for gastrointestinal disease, as well as the prognosis of gastrointestinal…
- Trial name
- ESPRESSO (NCT06371820)
- Testing
- ESPRESSO [The study has no intervention]
- Volunteers
- 13,000,000 people
- Sponsor
- Karolinska Institutet
Type 1 Diabetes, Autoimmune Diseases
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up
This study aims to describe the prevalence of additional autoimmune diseases and their specific antibodies at type 1 diabetes (T1D) diagnosis, and their incidence rate during follow-up, for children and adolescents.
- Conditions
- Type 1 Diabetes, Autoimmune Diseases, Hashimoto Disease, Graves Disease
- Trial name
- AADT1D (NCT04789993)
- Testing
- No intervention.
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Celiac Disease, Celiac
Celiac Disease and Diabetes Longitudinal Follow-up and Evaluation Study
To the investigators' knowledge, no single long-term prospective observational study has assessed dietary factors, diabetes clinical variables (metabolic control and associated complications), and self -perceived health and…
- Conditions
- Celiac Disease, Celiac, Diabetes Mellitus, Type 1
- Trial name
- CD-LiFE (NCT03122093)
- Where
- 6 sites in Canada
- Volunteers
- 90 people
- Sponsor
- The Hospital for Sick Children
Celiac Disease in Children
Validation of a New Innovative Method for Specific Marker Detection in Celiac Disease
Celiac disease (CD) is a common auto-immune disorder induced by gluten ingestion in genetically susceptible individuals (HLA-DQ2/DQ8).
- Trial name
- NCT06324539
- Testing
- Diagnostic Test: Rapid Intestinal anti-TG2 Assay
- Where
- 4 sites in Italy
- Volunteers
- 332 people
- Sponsor
- IRCCS Burlo Garofolo
Type 1 Diabetes, Celiac Disease
Combined Antibody Screening for Celiac and Diabetes Evaluation
The CASCADE Study (Combined Antibody Screening for Celiac and Diabetes Evaluation) is an observational study whose primary goal is to show that population-based screening for advanced prediction of type 1 diabetes (T1D) and…
- Trial name
- CASCADE (NCT04677699)
- Testing
- Combined Risk Score
- Where
- United States
- Volunteers
- 64,410 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest Research Institute
Celiac Disease
Gluten-free Diet Monitoring in Urine
The purpose of this study is to develope a novel method to determine gluten intake and to check gluten-free diet adherence in celiac patients by detection of gluten immunogenic peptides in urine.
- Trial name
- NCT02344758
- Testing
- Non-invasive lateral flow test for monitoring gluten intake, gluten-free diet (GFD), gluten-containing diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- University of Seville
Celiac Disease
Mass Screening for the Early Detection of Patients With Celiac Disease.
The use of a home rapid test for the detection of both gluten immunogenic peptides (GIP) in urine and immunoglobulin A (IgA) anti tissue transglutaminase (anti-tTG) antibodies in blood may contribute to the early detection of…
- Trial name
- NCT05186038
- Testing
- iVYCHECK GIP Urine, CeliacDetect
- Where
- 2 sites in Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Biomedal S.L.
Down Syndrome
An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You
The investigators conducted a national two-arm, randomized controlled trial of caregivers of individuals with DS to assess the efficacy of DSC2U in assuring adherence to evidence-based guidelines.
- Trial name
- DSC2U (NCT04227197)
- Testing
- Down Syndrome Clinic to You (DSC2U)
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bowel Disease, Crohn Disease
Development of New Diagnostic Tools in Capsule Endoscopy
Patients participating to this study will provide images and videos of capsule endoscopy to train, tune and evaluate technological bricks of artificial intelligence solutions, in order to improve diagnostic performances of the…
- Conditions
- Bowel Disease, Crohn Disease, Celiac Disease, Chronic Diarrhea
- Trial name
- NOCE (NCT06152289)
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Celiac Disease in Children, Anemia
Efficacy of Oral Sucrosomial Iron Supplementation in Children With Celiac Disease and Iron Deficiency or Anemia
Celiac disease in children is frequently associated with iron deficiency and/or iron deficiency anemia due to intestinal malabsorption and chronic inflammation.
- Conditions
- Celiac Disease in Children, Anemia, Iron Deficiencies
- Trial name
- NCT07563582
- Testing
- Sideral forte® VERUM drops
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Giannina Gaslini
Celiac Disease
No-biopsy Approach in Celiac Disease: Cut-off Points for IgA Anti-tissue Transglutaminase Assays
The main objective of this multicenter and observational study is to define the optimal threshold of different commercially available IgA anti-transglutaminase (tTG-IgA) antibody assays for celiac disease diagnosis (CD) avoiding…
- Trial name
- NCT05983978
- Where
- 6 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz